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Protein Ontology report - IRAK4:MYD88:TIRAP:activated TLR4 complex
PR:000027182 -
http://purl.obolibrary.org/obo/PR_000027182
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000027182
PRO name
IRAK4:MYD88:TIRAP:activated TLR4 complex
Synonyms
Other
:
EXACT:
IRAK4:MyD88:Mal:activated TLR4
Definition
"An IRAK4:MYD88:TIRAP:activated TLR complex that contains activated TLR4 receptor." [
PMID:12297423
, PRO:CNA, PRO:DAN, TLR:AMM]
Comment
Requested by=TLR.
PRO Category
complex
Parent
PR:000027193
IRAK4:MYD88:TIRAP:activated TLR complex
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Complex
1
Organism-Complex
3
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
comp.
In Complex?
complex
PR:000027182
IRAK4:MYD88:TIRAP:activated TLR4 complex
mIRAK4/UnMod
"An IRAK4:MYD88:TIRAP:activated TLR complex that contains activated TLR4 receptor." [PMID:12297423, PRO:CNA, PRO:DAN, TLR:AMM]
organism-complex
PR:000027183
IRAK4:MYD88:TIRAP:activated TLR4 complex (human)
mIRAK4/UnMod
"An IRAK4:MYD88:TIRAP:activated TLR4 complex in human that is composed of activated TLR4 receptor, the long isoform of MyD88, Tirap/Mal, and IRAK4." [PMID:12297423, PRO:CNA]
Yes
organism-complex
PR:000027187
IRAK4:MYD88:TIRAP:activated TLR4 complex (mouse)
TIRAP/iso:1
"An IRAK4:MYD88:TIRAP:activated TLR4 complex in mouse that is composed of activated TLR4 receptor, the long isoform of MyD88, Tirap/Mal, and IRAK4." [PMID:12538665, TLR:AMM]
organism-complex
PR:000027192
pIRAK4:MYD88:TIRAP:activated TLR4 complex (human)
hIRAK4/iso:1/Phos:1
"An IRAK4:MYD88:TIRAP:activated TLR4 complex in human that is composed of activated TLR4 receptor, MyD88, Tirap/Mal, and phosphorylated IRAK4." [PMID:17141195, PRO:CNA]
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000027183
mIRAK4/UnMod
acts_upstream_of_or_within
GO:0034142
toll-like receptor 4 signaling pathway
Reactome:REACT_6894
PR:000027192
hIRAK4/iso:1/Phos:1
acts_upstream_of_or_within
GO:0034142
toll-like receptor 4 signaling pathway
Reactome:REACT_6894