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Protein Ontology report - IRAK1:IRAK4:MYD88:TIRAP:activated TLR4
PR:000027219 - http://purl.obolibrary.org/obo/PR_000027219
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000027219   
  PRO nameIRAK1:IRAK4:MYD88:TIRAP:activated TLR4 
  Synonyms
Other: EXACT:IRAK1:IRAK4:MyD88:Mal:activated TLR4
  Definition"A protein-containing complex that is composed of the activated TLR4 receptor, Mal, MyD88, IRAK1 and IRAK4." [PMID:12538665, TLR:AMM] 
  CommentRequested by=TLR. 
  PRO Categorycomplex 
  ParentG0032991 protein-containing complex
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Complex1                                                  Organism-Complex 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
complex


PR:000027219
IRAK1:IRAK4:MYD88:TIRAP:activated TLR4
mTIRAP/Phos:1
"A protein-containing complex that is composed of the activated TLR4 receptor, Mal, MyD88, IRAK1 and IRAK4." [PMID:12538665, TLR:AMM]

organism-complex


PR:000027220
IRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse)
mTIRAP/Phos:1
"An IRAK1:IRAK4:MYD88:TIRAP:activated TLR4 whose components are encoded in the genome of mouse." [PMID:12538665, TLR:AMM]

organism-complex


PR:000027221
pIRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse)
mTIRAP/Phos:1
"An IRAK1:IRAK4:MYD88:TIRAP:activated TLR4 in mouse in which the IRAK1 subunit has been phosphorylated by IRAK4." [PMID:12538665, TLR:AMM]

organism-complex


PR:000027495
pIRAK1:pIRAK4:MYD88:TIRAP:activated TLR4 (human)
hIRAK1/iso:1/Phos:1
"An IRAK1:IRAK4:MYD88:TIRAP:activated TLR4 in human in which the IRAK1 subunit has been phosphorylated by IRAK4." [Reactome:R-HSA-166118]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000027495 hIRAK1/iso:1/Phos:1 acts_upstream_of_or_withinGO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894