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Protein Ontology report - estrogen receptor isoform 1
PR:000027721 - http://purl.obolibrary.org/obo/PR_000027721
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000027721   
  PRO nameestrogen receptor isoform 1 
  Synonyms
PRO-Short-label: EXACT:ESR1/iso:1
  Definition"An estrogen receptor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P03372-1 or a 1:1 ortholog thereof." [PMID:19940156, PRO:CNA] 
  PRO Categorysequence 
  ParentPR:000007204 estrogen receptor
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 1                                        
         Modification6                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Short Name

Ann. Has Annotation?

comp. In Complex?
sequence



PR:000027721 estrogen receptor isoform 1

ESR1/iso:1


organism-sequence



PR:P03372-1 estrogen receptor isoform 1 (human)

hESR1/iso:1


organism-modification



PR:000027724 estrogen receptor isoform 1 phosphorylated 1 (human)

hESR1/iso:1/Phos:1

Yes

organism-modification



PR:000027726 estrogen receptor isoform 1 phosphorylated 2 (human)

hESR1/iso:1/Phos:2

Yes

organism-modification



PR:000027754 estrogen receptor isoform 1 phosphorylated 3 (human)

hESR1/iso:1/Phos:3


organism-modification



PR:000027756 estrogen receptor isoform 1 acetylated 1 (human)

hESR1/iso:1/Ac:1

Yes

organism-modification



PR:000027776 estrogen receptor isoform 1 phosphorylated 4 (human)

hESR1/iso:1/Phos:4

Yes

organism-modification



PR:000027778 estrogen receptor isoform 1 phosphorylated 5 (human)

hESR1/iso:1/Phos:5


modification



PR:000027723 estrogen receptor isoform 1 phosphorylated 1

ESR1/iso:1/Phos:1


organism-modification



PR:000027724 estrogen receptor isoform 1 phosphorylated 1 (human)

hESR1/iso:1/Phos:1

Yes

modification



PR:000027725 estrogen receptor isoform 1 phosphorylated 2

ESR1/iso:1/Phos:2


organism-modification



PR:000027726 estrogen receptor isoform 1 phosphorylated 2 (human)

hESR1/iso:1/Phos:2

Yes

modification



PR:000027753 estrogen receptor isoform 1 phosphorylated 3

ESR1/iso:1/Phos:3


organism-modification



PR:000027754 estrogen receptor isoform 1 phosphorylated 3 (human)

hESR1/iso:1/Phos:3


modification



PR:000027755 estrogen receptor isoform 1 acetylated 1

ESR1/iso:1/Ac:1


organism-modification



PR:000027756 estrogen receptor isoform 1 acetylated 1 (human)

hESR1/iso:1/Ac:1

Yes

modification



PR:000027775 estrogen receptor isoform 1 phosphorylated 4

ESR1/iso:1/Phos:4


organism-modification



PR:000027776 estrogen receptor isoform 1 phosphorylated 4 (human)

hESR1/iso:1/Phos:4

Yes

modification



PR:000027777 estrogen receptor isoform 1 phosphorylated 5

ESR1/iso:1/Phos:5


organism-modification



PR:000027778 estrogen receptor isoform 1 phosphorylated 5 (human)

hESR1/iso:1/Phos:5


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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0010628 positive regulation of gene expressionPR:000027726 hESR1/iso:1/Phos:2 PMID:20101225
PR:000027776 hESR1/iso:1/Phos:4 PMID:12138194
GO:0045893 positive regulation of DNA-templated transcriptionPR:000027724 hESR1/iso:1/Phos:1 PMID:19940156

Molecular Function GO Term

Protein Forms & Complexes

Evidence
GO:0003677 DNA bindingPR:000027756 hESR1/iso:1/Ac:1 PMID:16497729
GO:0042803 protein homodimerization activityPR:000027726 hESR1/iso:1/Phos:2 PMID:20101225

Cellular Location GO Term

Protein Forms & Complexes

Evidence
GO:0005634 nucleusPR:000027726 hESR1/iso:1/Phos:2 PMID:20101225
PR:000027776 hESR1/iso:1/Phos:4 PMID:12138194