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Protein Ontology report - cellular tumor antigen p53 isoform 1 ubiquitinated 1
PR:000027805 -
http://purl.obolibrary.org/obo/PR_000027805
Protein Forms
Ontology Information
Show OBO stanza
PRO ID
PR:000027805
PRO name
cellular tumor antigen p53 isoform 1 ubiquitinated 1
Synonyms
PRO-Short-label
:
EXACT:
TP53/iso:1/Ubiq:1
Definition
"A cellular tumor antigen p53 isoform 1 that has been ubiquitinated at two highly conserved Lys residues in the C-terminal region of the DNA-binding domain. This modification promotes proteasomal degradation of p53. Example:
UniProtKB:P04637-1
, Lys-291/Lys-292,
MOD:01148
." [
PMID:19536131
, PRO:PD]
PRO Category
modification
Parent
PR:000003036
cellular tumor antigen p53 isoform 1
PR:000037077
ubiquitinated protein
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
comp.
In Complex?
modification
PR:000027805
cellular tumor antigen p53 isoform 1 ubiquitinated 1
TP53/iso:1/Ubiq:1
"A cellular tumor antigen p53 isoform 1 that has been ubiquitinated at two highly conserved Lys residues in the C-terminal region of the DNA-binding domain. This modification promotes proteasomal degradation of p53. Example: UniProtKB:P04637-1, Lys-291/Lys-292, MOD:01148." [PMID:19536131, PRO:PD]
organism-modification
PR:000027806
cellular tumor antigen p53 isoform 1 ubiquitinated 1 (human)
hTP53/iso:1/Ubiq:1
"A cellular tumor antigen p53 isoform 1 ubiquitinated 1 in human. UniProtKB:P04637-1, Lys-291/Lys-292, MOD:01148." [PMID:19536131, PRO:PD]
