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Protein Ontology report - cellular tumor antigen p53 isoform 1 methylated 3
PR:000027807 - http://purl.obolibrary.org/obo/PR_000027807
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000027807   
  PRO namecellular tumor antigen p53 isoform 1 methylated 3 
  Synonyms
PRO-Short-label: EXACT:TP53/iso:1/Me:3
  Definition"A cellular tumor antigen p53 isoform 1 that has been methylated at the second Lys residue of the [KR]-[STA]-K motif within the C-terminal regulatory region. Example: UniProtKB:P04637-1, Lys-372, MOD:00663." [PMID:15525938, PRO:PD] 
  PRO Categorymodification 
  ParentPR:000003036 cellular tumor antigen p53 isoform 1
PR:000037074 methylated protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
modification


PR:000027807
cellular tumor antigen p53 isoform 1 methylated 3
TP53/iso:1/Me:3
"A cellular tumor antigen p53 isoform 1 that has been methylated at the second Lys residue of the [KR]-[STA]-K motif within the C-terminal regulatory region. Example: UniProtKB:P04637-1, Lys-372, MOD:00663." [PMID:15525938, PRO:PD]

organism-modification


PR:000027808
cellular tumor antigen p53 isoform 1 methylated 3 (human)
hTP53/iso:1/Me:3
"A cellular tumor antigen p53 isoform 1 methylated 3 in human. This modification promotes p53 stability and inhibits Smyd2 mediated p53 methylation at Lys-370. UniProtKB:P04637-1, Lys-372, MOD:00663." [PMID:15525938, PRO:PD]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000027808 hTP53/iso:1/Me:3
UniProtKB:P04637-1, Lys-372, MOD:00663		 acts_upstream_of_or_withinGO:0045893 positive regulation of DNA-templated transcription PMID:15525938
located_inGO:0005634 nucleus PMID:15525938