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Protein Ontology report - cellular tumor antigen p53 isoform 1 O-glycosylated 1
PR:000027834 -
http://purl.obolibrary.org/obo/PR_000027834
Protein Forms
Ontology Information
Show OBO stanza
PRO ID
PR:000027834
PRO name
cellular tumor antigen p53 isoform 1 O-glycosylated 1
Synonyms
PRO-Short-label
:
EXACT:
TP53/iso:1/OGlyco:1
Definition
"A cellular tumor antigen p53 isoform 1 that has been O-glycosylated on a Ser residue located in the DNA-binding domain. This modification stabilizes p53 by blocking ubiquitin-dependent proteolysis and also inhibits phosphorylation of p53 at Thr-155. Example:
UniProtKB:P04637-1
, Ser-149,
MOD:00805
|Thr-155,
PR:000026291
." [
PMID:16964247
, PRO:DAN, PRO:PD]
PRO Category
modification
Parent
PR:000003036
cellular tumor antigen p53 isoform 1
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
comp.
In Complex?
modification
PR:000027834
cellular tumor antigen p53 isoform 1 O-glycosylated 1
TP53/iso:1/OGlyco:1
"A cellular tumor antigen p53 isoform 1 that has been O-glycosylated on a Ser residue located in the DNA-binding domain. This modification stabilizes p53 by blocking ubiquitin-dependent proteolysis and also inhibits phosphorylation of p53 at Thr-155. Example: UniProtKB:P04637-1, Ser-149, MOD:00805|Thr-155, PR:000026291." [PMID:16964247, PRO:DAN, PRO:PD]
organism-modification
PR:000027835
cellular tumor antigen p53 isoform 1 O-glycosylated 1 (human)
hTP53/iso:1/OGlyco:1
"A cellular tumor antigen p53 isoform 1 O-glycosylated 1 in human. UniProtKB:P04637-1, Ser-149, MOD:00805|Thr-155, PR:000026291." [PMID:16964247, PRO:PD]