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Protein Ontology report - pro-neuregulin-1, membrane-bound isoform proteolytic cleavage product
PR:000029651 - http://purl.obolibrary.org/obo/PR_000029651
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000029651   
  PRO namepro-neuregulin-1, membrane-bound isoform proteolytic cleavage product 
  Synonyms
PRO-Short-label: EXACT:NRG1/ClvPrd
  Definition"A pro-neuregulin-1, membrane-bound isoform that has been processed by proteolytic cleavage." [PRO:DNx] 
  PRO Categorymodification 
  ParentPR:000018264 proteolytic cleavage product
PR:000029649 pro-neuregulin-1, membrane-bound isoform
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
modification


PR:000029651 pro-neuregulin-1, membrane-bound isoform proteolytic cleavage product
NRG1/ClvPrd

organism-modification


PR:000044821 neuregulin-1 type I-beta1a mature form (mouse)
mNRG1/iso:Ibeta1a/mature
Yes
organism-modification


PR:000044839 neuregulin-1 type I-beta4a mature form (mouse)
mNRG1/iso:Ibeta4a/mature

organism-modification


PR:000044843 neuregulin-1 intracellular domain (mouse)
mNRG1/Clv:intracellular
Yes
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0022008 neurogenesisPR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
NOT GO:0045773 positive regulation of axon extensionPR:000044843 mNRG1/Clv:intracellular MGI_ref:4461331; PMID:20610754
GO:0045944 positive regulation of transcription by RNA polymerase IIPR:000044843 mNRG1/Clv:intracellular MGI_ref:4461331; PMID:20610754
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylationPR:000044821 mNRG1/iso:Ibeta1a/mature MGI_ref:3625788; PMID:11116142

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0005515 protein bindingPR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005576 extracellular regionPR:000044821 mNRG1/iso:Ibeta1a/mature MGI_ref:3625788; PMID:11116142
GO:0005634 nucleusPR:000044843 mNRG1/Clv:intracellular MGI_ref:4461331; PMID:20610754