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Protein Ontology report - pro-neuregulin-1, membrane-bound isoform proteolytic cleavage product
PR:000029651 - http://purl.obolibrary.org/obo/PR_000029651
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000029651   
  PRO namepro-neuregulin-1, membrane-bound isoform proteolytic cleavage product 
  Synonyms
PRO-Short-label: EXACT:NRG1/ClvPrd
  Definition"A pro-neuregulin-1, membrane-bound isoform that has been processed by proteolytic cleavage." [PRO:DNx] 
  PRO Categorymodification 
  ParentPR:000018264 proteolytic cleavage product
PR:000029649 pro-neuregulin-1, membrane-bound isoform
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
modification


PR:000029651 pro-neuregulin-1, membrane-bound isoform proteolytic cleavage product
NRG1/ClvPrd

organism-modification


PR:000044821 neuregulin-1 type I-beta1a mature form (mouse)
mNRG1/iso:Ibeta1a/mature
Yes
organism-modification


PR:000044839 neuregulin-1 type I-beta4a mature form (mouse)
mNRG1/iso:Ibeta4a/mature

organism-modification


PR:000044843 neuregulin-1 intracellular domain (mouse)
mNRG1/Clv:intracellular
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000044821 mNRG1/iso:Ibeta1a/mature acts_upstream_of_or_withinGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation MGI_ref:3625788; PMID:11116142
located_inGO:0005576 extracellular region MGI_ref:3625788; PMID:11116142
PR:000044843 mNRG1/Clv:intracellular
Example: UniProtKB:Q6DR99, 326-700		 acts_upstream_of_or_withinGO:0022008 neurogenesis MGI_ref:4438553; PMID:19781646
GO:0022008 neurogenesis MGI_ref:4438553; PMID:19781646
NOT GO:0045773 positive regulation of axon extension MGI_ref:4461331; PMID:20610754
GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:4461331; PMID:20610754
enablesGO:0005515 protein binding with PR:O54941 Baf57 MGI_ref:4438553; PMID:19781646
located_inGO:0005634 nucleus MGI_ref:4461331; PMID:20610754