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Protein Ontology report - lysosomal cobalamin transport escort protein LMBD1
PR:000032677 - http://purl.obolibrary.org/obo/PR_000032677
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000032677   
  PRO namelysosomal cobalamin transport escort protein LMBD1 
  Synonyms
PRO-Short-label: EXACT:LMBRD1
Gene-based: RELATED:BM-021 | C6orf209 | CD001 | MSTP044 | NESI
Other: EXACT:HDAg-L-interacting protein NESI | LMBD1 | LMBR1 domain-containing protein 1 | nuclear export signal-interacting protein
  Definition"A protein that is a translation product of the human LMBRD1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 7                                        
         Sequence1                                                  Organism-Sequence 8                                        
         Modification0                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
gene


PR:000032677
lysosomal cobalamin transport escort protein LMBD1
LMBRD1
"A protein that is a translation product of the human LMBRD1 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:Q54KD1
probable lysosomal cobalamin transporter (Dictyostelium discoideum)
Dicty-LMBRD1
"A lysosomal cobalamin transport escort protein LMBD1 that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54KD1, PRO:DNx]

organism-gene


PR:Q5PR61
lysosomal cobalamin transport escort protein LMBD1 (zebrafish)
z-LMBRD1
"A lysosomal cobalamin transport escort protein LMBD1 that is encoded in the genome of zebrafish." [PRO:DNx]

organism-gene


PR:Q5ZI05
lysosomal cobalamin transport escort protein LMBD1 (chicken)
chick-LMBRD1
"A lysosomal cobalamin transport escort protein LMBD1 that is encoded in the genome of chicken." [PRO:DNx]

organism-gene


PR:Q6AZ61
lysosomal cobalamin transport escort protein LMBD1 (rat)
rLMBRD1
"A lysosomal cobalamin transport escort protein LMBD1 that is encoded in the genome of rat." [OMA:Q6AZ61, PRO:DNx]

organism-sequence


PR:Q6AZ61-1
lysosomal cobalamin transport escort protein LMBD1 isoform 1 (rat)
rLMBRD1/iso:1
"A lysosomal cobalamin transport escort protein LMBD1 isoform 1 that is encoded in the genome of rat." [PRO:CNA, UniProtKB:Q6AZ61]

organism-gene


PR:Q8K0B2
lysosomal cobalamin transport escort protein LMBD1 (mouse)
mLMBRD1
"A lysosomal cobalamin transport escort protein LMBD1 that is encoded in the genome of mouse." [OMA:Q8K0B2, PRO:DNx]

organism-sequence


PR:Q8K0B2-1
lysosomal cobalamin transport escort protein LMBD1 isoform 1 (mouse)
mLMBRD1/iso:1
"A lysosomal cobalamin transport escort protein LMBD1 isoform 1 that is encoded in the genome of mouse." [PMID:16141072, PRO:HJD]
Yes
organism-sequence


PR:Q8K0B2-2
lysosomal cobalamin transport escort protein LMBD1 isoform 2 (mouse)
mLMBRD1/iso:2
"A lysosomal cobalamin transport escort protein LMBD1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8K0B2-2." [PMID:16141072, PRO:HJD]

organism-sequence


PR:Q8K0B2-3
lysosomal cobalamin transport escort protein LMBD1 isoform 3 (mouse)
mLMBRD1/iso:3
"A lysosomal cobalamin transport escort protein LMBD1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8K0B2-3." [PMID:16141072, PRO:HJD]

organism-gene


PR:Q9M028
LIMR family protein At5g01460 (Arabidopsis thaliana)
At-LMBRD1
"A lysosomal cobalamin transport escort protein LMBD1 that is encoded in the genome of Arabidopsis thaliana." [PRO:DNx]

organism-gene


PR:Q9NUN5
lysosomal cobalamin transport escort protein LMBD1 (human)
hLMBRD1
"A lysosomal cobalamin transport escort protein LMBD1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9NUN5]

organism-sequence


PR:Q9NUN5-1
lysosomal cobalamin transport escort protein LMBD1 isoform h1 (human)
hLMBRD1/iso:h1
"A lysosomal cobalamin transport escort protein LMBD1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NUN5-1." [PRO:DNx, UniProtKB:Q9NUN5]

organism-sequence


PR:Q9NUN5-2
lysosomal cobalamin transport escort protein LMBD1 isoform h2 (human)
hLMBRD1/iso:h2
"A lysosomal cobalamin transport escort protein LMBD1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NUN5-2." [PRO:DNx, UniProtKB:Q9NUN5]

organism-sequence


PR:Q9NUN5-3
lysosomal cobalamin transport escort protein LMBD1 isoform h3 (human)
hLMBRD1/iso:h3
"A lysosomal cobalamin transport escort protein LMBD1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NUN5-3." [PRO:DNx, UniProtKB:Q9NUN5]

organism-sequence


PR:Q9NUN5-4
lysosomal cobalamin transport escort protein LMBD1 isoform h4 (human)
hLMBRD1/iso:h4
"A lysosomal cobalamin transport escort protein LMBD1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NUN5-4." [PRO:DNx, UniProtKB:Q9NUN5]

organism-modification


PR:000067562
lysosomal cobalamin transport escort protein LMBD1 deaminated 1 (human)
hLMBRD1/Deam:1
"A lysosomal cobalamin transport escort protein LMBD1 (human) that has been deaminated on the residue at the position equivalent to Asn-78 of the amino acid sequence represented by UniProtKB:Q9NUN5-1. Example: UniProtKB:Q9NUN5-1, Asn-78, MOD:00684." [IEDB_epitope:1594014, PRO:DNx]

sequence


PR:000037483
lysosomal cobalamin transport escort protein LMBD1 isoform 1
LMBRD1/iso:1
"A lysosomal cobalamin transport escort protein LMBD1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8K0B2-1 or a 1:1 ortholog thereof." [PMID:16141072, PRO:HJD]

organism-sequence


PR:Q6AZ61-1
lysosomal cobalamin transport escort protein LMBD1 isoform 1 (rat)
rLMBRD1/iso:1
"A lysosomal cobalamin transport escort protein LMBD1 isoform 1 that is encoded in the genome of rat." [PRO:CNA, UniProtKB:Q6AZ61]

organism-sequence


PR:Q8K0B2-1
lysosomal cobalamin transport escort protein LMBD1 isoform 1 (mouse)
mLMBRD1/iso:1
"A lysosomal cobalamin transport escort protein LMBD1 isoform 1 that is encoded in the genome of mouse." [PMID:16141072, PRO:HJD]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q8K0B2-1 mLMBRD1/iso:1 acts_upstream_of_or_withinGO:0038016 insulin receptor internalization MGI_ref:5543853; PMID:24078630
NOT GO:0043408 regulation of MAPK cascade MGI_ref:5543853; PMID:24078630
GO:0046325 negative regulation of glucose import MGI_ref:5543853; PMID:24078630
GO:0046627 negative regulation of insulin receptor signaling pathway MGI_ref:5543853; PMID:24078630
GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction MGI_ref:5543853; PMID:24078630