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Protein Ontology report - mitotic checkpoint serine/threonine-protein kinase BUB1 CDK-consensus sites phosphorylated 6 (Schizosaccharomyces pombe 972h-)

PR:000035411 - http://purl.obolibrary.org/obo/PR_000035411

Annotations

Ontology Information

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PAF

GPI

PRO ID

PR:000035411

PRO name

mitotic checkpoint serine/threonine-protein kinase BUB1 CDK-consensus sites phosphorylated 6 (Schizosaccharomyces pombe 972h-)

Synonyms

PRO-Short-label:	EXACT:	Spom972h-BUB1/Phos:6
PRO-proteoform-std:	EXACT:	UniProtKB:O94751, (Thr-340, MOD:00047 and/or Thr-423, MOD:00047 and/or Thr-455, MOD:00047 and/or Ser-466, MOD:00046)

Definition

"A BUB1 CDK-consensus sites phosphorylated form in Schizosaccharomyces pombe 972h-. The exact combination of phosphorylated sites is not known but may involve Thr-340, Thr-423, Thr-455, and/or Ser-466 of the amino acid sequence represented by UniProtKB:O94751. UniProtKB:O94751, (Thr-340, MOD:00047 and/or Thr-423, MOD:00047 and/or Thr-455, MOD:00047 and/or Ser-466, MOD:00046)." [PMID:12606573, PRO:DAN, PRO:KER]

Comment

Note: Phosphorylation occurs during Meiosis I or spindle disruption (tubulin mutant). Kinase=("CDC2"; PR:P04551; Thr-340 and/or Thr-423 and/or Thr-455 and/or Ser-466).

PRO Category

organism-modification

Parent

PR:000029043 Schizosaccharomyces pombe 972h- protein
PR:000035413 BUB1 CDK-consensus sites phosphorylated form
PR:000037070 phosphoprotein

Taxon

NCBITaxon:284812 Schizosaccharomyces pombe 972h-

Term Hierarchy
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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:000035411 Spom972h-BUB1/Phos:6 UniProtKB:O94751, (Thr-340, MOD:00047 and/or Thr-423, MOD:00047 and/or Thr-455, MOD:00047 and/or Ser-466, MOD:00046)	acts_upstream_of_or_within	GO:0007094 mitotic spindle assembly checkpoint signaling	PMID:12606573
	acts_upstream_of_or_within	GO:0045143 homologous chromosome segregation	PMID:12606573
	located_in	GO:0000776 kinetochore	PMID:12606573