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Protein Ontology report - BUB1 CDK-consensus sites phosphorylated form
PR:000035413 - http://purl.obolibrary.org/obo/PR_000035413
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000035413   
  PRO nameBUB1 CDK-consensus sites phosphorylated form 
  Synonyms
PRO-Short-label: EXACT:BUB1/PhosRes+
  Definition"A mitotic checkpoint serine/threonine-protein kinase BUB1 that is phosphorylated on CDK consensus sites (S/T-P-X-K/R) located in the middle region of BUB1." [PMID:12606573, PMID:16760428, PRO:KER] 
  PRO Categorymodification 
  ParentPR:000004854 mitotic checkpoint serine/threonine-protein kinase BUB1
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
modification



PR:000035413

BUB1 CDK-consensus sites phosphorylated form

BUB1/PhosRes+


"A mitotic checkpoint serine/threonine-protein kinase BUB1 that is phosphorylated on CDK consensus sites (S/T-P-X-K/R) located in the middle region of BUB1." [PMID:12606573, PMID:16760428, PRO:KER]


organism-modification



PR:000035411

mitotic checkpoint serine/threonine-protein kinase BUB1 CDK-consensus sites phosphorylated 6 (Schizosaccharomyces pombe 972h-)

Spom972h-BUB1/Phos:6


"A BUB1 CDK-consensus sites phosphorylated form in Schizosaccharomyces pombe 972h-. The exact combination of phosphorylated sites is not known but may involve Thr-340, Thr-423, Thr-455, and/or Ser-466 of the amino acid sequence represented by UniProtKB:O94751. UniProtKB:O94751, (Thr-340, MOD:00047 and/or Thr-423, MOD:00047 and/or Thr-455, MOD:00047 and/or Ser-466, MOD:00046)." [PMID:12606573, PRO:DAN, PRO:KER]

Yes

organism-modification



PR:000035412

mitotic checkpoint serine/threonine-protein kinase BUB1 CDK-consensus sites phosphorylated 7 (human)

hBUB1/Phos:7


"A BUB1 CDK-consensus sites phosphorylated form in human. Phosphorylation occurs during mitosis and spindle disruption (e.g. with nocodazole). Thr-609 phosphorylation is critical for interaction with PLK1. Example: UniProtKB:O43683-1, Ser-593, MOD:00046|Thr-609, MOD:00047." [PMID:16760428, PRO:KER]

Yes

Yes
organism-modification



PR:000035419

mitotic checkpoint serine/threonine-protein kinase BUB1 CDK-consensus sites phosphorylated 1 (yeast)

yBUB1/Phos:CDK-1


"A BUB1 CDK-consensus sites phosphorylated form in yeast that has phosphorylation at Thr-566. This phosphorylation is essential for deactivating the spindle checkpoint in anaphase and adaptation to prolonged mitotic arrest. UniProtKB:P41695, Thr-566, MOD:00047." [PMID:21298086, PRO:KER]

Yes

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BUB1/PhosRes+ forms found in complexes   

BUB1/PhosRes+ Component
Complexes
PR:000035412 hBUB1/Phos:7 PR:000035581 phosphoBUB1:PLK1 complex (human)
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0007094 mitotic spindle assembly checkpoint signalingPR:000035411 Spom972h-BUB1/Phos:6 PMID:12606573
NOT GO:0031577 spindle checkpoint signalingPR:000035419 yBUB1/Phos:CDK-1 PMID:21298086
GO:0034501 protein localization to kinetochorePR:000035412 hBUB1/Phos:7 PMID:16760428
GO:0045143 homologous chromosome segregationPR:000035411 Spom972h-BUB1/Phos:6 PMID:12606573

Molecular Function GO Term

Protein Forms & Complexes

Evidence
GO:0005515 protein bindingPR:000035412 hBUB1/Phos:7 PMID:16760428

Cellular Location GO Term

Protein Forms & Complexes

Evidence
GO:0000776 kinetochorePR:000035411 Spom972h-BUB1/Phos:6 PMID:12606573