Home |   Linked Open Data |   Browse |   Search |   Statistics |   Download  RACE-PRO  PRO tracker  Community  PRO Consortium  Publications  Documentation

Protein Ontology report - mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 4 (human) PR:000035435 - http://purl.obolibrary.org/obo/PR_000035435        Annotations       Ontology Information Show OBO stanza / PAF / GPI   PRO ID PR:000035435      PRO name mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 4 (human)    Synonyms PRO-Short-label: EXACT: hBUB1B/Phos:4 PRO-proteoform-std: EXACT: UniProtKB:O60566, Ser-543/Ser-670/Ser-1043, MOD:00046 NARROW: UniProtKB:O60566-1, Ser-543/Ser-670/Ser-1043, MOD:00046 Other: RELATED: BUBR1 phosphorylated (human) | hBUBR1 phosphorylated   Definition "A mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 4 in human. This phosphorylated form is observed in prophase, prometaphase, metaphase, anaphase, spindle depolymerization (nocodazole). This form is not observed when there is a lack of kinetochore tension (taxol). Ser-435, Ser-574 and Ser-720 could also be phosphorylated. Example: UniProtKB:O60566-1, Ser-543/Ser-670/Ser-1043, MOD:00046." [PMID:19015317, PMID:20016069, PRO:KER]    Comment Kinase=("CDK1"; PR:000003271; Ser-543/Ser-670/Ser-1043).    PRO Category organism-modification    Parent PR:000035434 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 4 PR:O60566 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (human)   Taxon NCBITaxon:9606 Homo sapiens   Term Hierarchy   Visualization DAG: OLS: Back to top Functional Annotation (PRO-centric view) Switch to GO Centric View    PRO Term GO Annotation Evidence PR:000035435 hBUB1B/Phos:4 Example: UniProtKB:O60566-1, Ser-543/Ser-670/Ser-1043, MOD:00046 acts_upstream_of_or_within increased GO:0008608 attachment of spindle microtubules to kinetochore relative to PR:000035373 hBUB1B/PhosRes- PMID:19015317; PMID:20016069 increased GO:0051310 metaphase chromosome alignment relative to PR:000035373 hBUB1B/PhosRes- PMID:20016069 located_in GO:0000776 kinetochore PMID:19015317