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Protein Ontology report - F-actin-capping protein subunit beta isoform 2
PR:000035826 - http://purl.obolibrary.org/obo/PR_000035826
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000035826   
  PRO nameF-actin-capping protein subunit beta isoform 2 
  Synonyms
PRO-Short-label: EXACT:CAPZB/iso:2
  Definition"An F-actin-capping protein subunit beta that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P47757-2 or a 1:1 ortholog thereof." [PMID:10601341, PRO:KRC] 
  PRO Categorysequence 
  ParentPR:000005032 F-actin-capping protein subunit beta
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
sequence


PR:000035826
F-actin-capping protein subunit beta isoform 2
CAPZB/iso:2
"An F-actin-capping protein subunit beta that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P47757-2 or a 1:1 ortholog thereof." [PMID:10601341, PRO:KRC]

organism-sequence


PR:P47757-2
F-actin-capping protein subunit beta isoform 2 (mouse)
mCAPZB/iso:2
"An F-actin-capping protein subunit beta isoform 2 that is encoded in the genome of mouse." [PMID:10601341, PRO:KRC]
Yes
Yes
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CAPZB/iso:2 forms found in complexes   

CAPZB/iso:2 Component
 Complexes
PR:P47757ZDASHZ2 mCAPZB/iso:2 PR:000035900 F-actin capping protein complex alpha-1 beta-2 (mouse)
PR:000035901 F-actin capping protein complex alpha-2 beta-2 (mouse)
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0030032 lamellipodium assemblyPR:P47757-2 mCAPZB/iso:2 MGI_ref:4397629; PMID:19806181
GO:0031115 negative regulation of microtubule polymerizationPR:P47757-2 mCAPZB/iso:2 MGI_ref:4397629; PMID:19806181
GO:0031175 neuron projection developmentPR:P47757-2 mCAPZB/iso:2 MGI_ref:4397629; PMID:19806181
GO:0051016 barbed-end actin filament cappingPR:P47757-2 mCAPZB/iso:2 MGI_ref:3758397; PMID:17656356
GO:0055001 muscle cell developmentPR:P47757-2 mCAPZB/iso:2 MGI_ref:1350695; PMID:10601341

Molecular Function GO Term
Protein Forms & Complexes
Evidence
contributes_to GO:0005515 protein bindingPR:P47757-2 mCAPZB/iso:2 MGI_ref:3773286; PMID:11604420
GO:0048487 beta-tubulin bindingPR:P47757-2 mCAPZB/iso:2 MGI_ref:4397629; PMID:19806181
contributes_to GO:0051015 actin filament bindingPR:P47757-2 mCAPZB/iso:2 MGI_ref:3758397; PMID:17656356

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0008290 F-actin capping protein complexPR:P47757-2 mCAPZB/iso:2 MGI_ref:4397629; PMID:19806181
PR:P47757-2 mCAPZB/iso:2 MGI_ref:4397629; PMID:19806181
GO:0014704 intercalated discPR:P47757-2 mCAPZB/iso:2 MGI_ref:68935; PMID:7929588
PR:P47757-2 mCAPZB/iso:2 MGI_ref:68935; PMID:7929588