back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

|   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - GSK3-like glycogen synthase kinase
PR:000035899 - http://purl.obolibrary.org/obo/PR_000035899
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000035899   
  PRO nameGSK3-like glycogen synthase kinase 
  Definition"A protein that contains a copy of the Protein kinase (Pfam:PF00069) domain and normally functions as a non-receptor serine/threonine protein kinase that is involved in a variety of biological processes, such as developmental signalling pathways and also regulation of the cytoskeleton." [PMID:16504046, PMID:22051150
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family2                                                  Organism-Family 0                                        
         Gene4                                                  Organism-Gene 14                                        
         Sequence1                                                  Organism-Sequence 10                                        
         Modification4                                                  Organism-Modification 18                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
PIRSF:PIRSF501136
Back to top
Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
family



PR:000035899

GSK3-like glycogen synthase kinase

At-ASKtheta/PhosRes-


"A protein that contains a copy of the Protein kinase (Pfam:PF00069) domain and normally functions as a non-receptor serine/threonine protein kinase that is involved in a variety of biological processes, such as developmental signalling pathways and also regulation of the cytoskeleton." [PMID:16504046, PMID:22051150]


gene



PR:000035393

shaggy-related protein kinase eta

ASK7


"A GSK3-like glycogen synthase kinase that is a translation product of the Arabidopsis thaliana ASK7 gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:Q39011

shaggy-related protein kinase eta (Arabidopsis thaliana)

At-ASK7


"A shaggy-related protein kinase eta that is encoded in the genome of Arabidopsis thaliana." [PRO:LVM]

Yes

organism-sequence



PR:Q39011-1

shaggy-related protein kinase eta isoform 1 (Arabidopsis thaliana)

At-ASK7/iso:1


"A shaggy-related protein kinase eta (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q39011-1." [PRO:DNx, UniProtKB:Q39011]


organism-sequence



PR:Q39011-2

shaggy-related protein kinase eta isoform 2 (Arabidopsis thaliana)

At-ASK7/iso:2


"A shaggy-related protein kinase eta (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q39011-2." [PRO:DNx, UniProtKB:Q39011]


organism-modification



PR:000035742

shaggy-related protein kinase eta phosphorylated 1 (Arabidopsis thaliana)

At-ASK7/Phos:1


"A shaggy-related protein kinase eta phosphorylated 1 in Arabidopsis thaliana. Example: UniProtKB:Q39011-1, Tyr-200, MOD:00048." [PMID:21855796, PRO:LVM]

Yes

organism-modification



PR:000035971

shaggy-related protein kinase eta unphosphorylated form (Arabidopsis thaliana)

At-ASK7/PhosRes-


"A shaggy-related protein kinase eta unphosphorylated form in Arabidopsis thaliana." [PRO:LVM]

Yes

modification



PR:000035741

shaggy-related protein kinase eta phosphorylated 1

ASK7/Phos:1


"A shaggy-related protein kinase eta that has been phosphorylated on the Tyr residue in the sequence ISYICSR located in the Protein kinase domain (Pfam:PF00069). Example: UniProtKB:Q39011, Tyr-200, MOD:00048." [PMID:21855796, PRO:CNA]


organism-modification



PR:000035742

shaggy-related protein kinase eta phosphorylated 1 (Arabidopsis thaliana)

At-ASK7/Phos:1


"A shaggy-related protein kinase eta phosphorylated 1 in Arabidopsis thaliana. Example: UniProtKB:Q39011-1, Tyr-200, MOD:00048." [PMID:21855796, PRO:LVM]

Yes

modification



PR:000035970

shaggy-related protein kinase eta unphosphorylated form

ASK7/PhosRes-


"A shaggy-related protein kinase eta that lacks phosphorylated residues." [PRO:LVM]


organism-modification



PR:000035971

shaggy-related protein kinase eta unphosphorylated form (Arabidopsis thaliana)

At-ASK7/PhosRes-


"A shaggy-related protein kinase eta unphosphorylated form in Arabidopsis thaliana." [PRO:LVM]

Yes

gene



PR:000035887

shaggy-related protein kinase theta

ASK8


"A GSK3-like glycogen synthase kinase that is a translation product of the Arabidopsis thaliana ASK8 gene or a 1:1 ortholog thereof." [PMID:20128883, PRO:LVM]


organism-gene



PR:Q96287

shaggy-related protein kinase theta (Arabidopsis thaliana)

At-ASKtheta


"A shaggy-related protein kinase theta that is encoded in the genome of Arabidopsis thaliana." [PRO:LVM]


organism-modification



PR:000035889

shaggy-related protein kinase theta phosphorylated 1 (Arabidopsis thaliana)

At-ASKtheta/Phos:1


"A shaggy-related protein kinase theta phosphorylated 1 in Arabidopsis thaliana." [PMID:20128883, PRO:LVM]

Yes

organism-modification



PR:000035898

shaggy-related protein kinase theta unphosphorylated form (Arabidopsis thaliana)

At-ASKtheta/PhosRes-


"A shaggy-related protein kinase theta unphosphorylated form in Arabidopsis thaliana." [PMID:20128883, PRO:LVM]

Yes

modification



PR:000035888

shaggy-related protein kinase theta phosphorylated 1

ASKtheta/Phos:1


"A shaggy-related protein kinase theta that has been phosphorylated by autocatalysis." [PMID:20128883, PRO:LVM]


organism-modification



PR:000035889

shaggy-related protein kinase theta phosphorylated 1 (Arabidopsis thaliana)

At-ASKtheta/Phos:1


"A shaggy-related protein kinase theta phosphorylated 1 in Arabidopsis thaliana." [PMID:20128883, PRO:LVM]

Yes

modification



PR:000035897

shaggy-related protein kinase theta unphosphorylated form

ASKtheta/PhosRes-


"A shaggy-related protein kinase theta that lacks phosphorylated residues." [PRO:CNA]


organism-modification



PR:000035898

shaggy-related protein kinase theta unphosphorylated form (Arabidopsis thaliana)

At-ASKtheta/PhosRes-


"A shaggy-related protein kinase theta unphosphorylated form in Arabidopsis thaliana." [PMID:20128883, PRO:LVM]

Yes

family



PR:000050019

glycogen synthase kinase 3

fam:GSK3


"A GSK3-like glycogen synthase kinase that is a translation product of the human GSK3A or GSK3B genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:DAN]


gene



PR:000008287

glycogen synthase kinase-3 alpha

GSK3A


"A glycogen synthase kinase 3 that is a translation product of the human GSK3A gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P18265

glycogen synthase kinase-3 alpha (rat)

rGSK3A


"A glycogen synthase kinase-3 alpha that is encoded in the genome of rat." [OMA:P18265, PRO:DNx]


organism-modification



PR:000046146

glycogen synthase kinase-3 alpha phosphorylated 1 (rat)

rGsk3a/Phos:1


"A glycogen synthase kinase-3 alpha (rat) that has been phosphorylated at Ser-21. UniProtKB:P18265, Ser-21, MOD:00046." [iPTMnet:P18265, PMID:11978789]


organism-gene



PR:P49840

glycogen synthase kinase-3 alpha (human)

hGSK3A


"A glycogen synthase kinase-3 alpha that is encoded in the genome of human." [PRO:DNx, UniProtKB:P49840]


organism-modification



PR:000045808

glycogen synthase kinase-3 alpha phosphorylated 1 (human)

hGSK3A/Phos:1


"A glycogen synthase kinase-3 alpha (human) that has been phosphorylated at Ser-21. UniProtKB:P49840, Ser-21, MOD:00046." [iPTMnet:P49840, PMID:11035810]


organism-modification



PR:000047634

glycogen synthase kinase-3 alpha, initiator methionine removed form (human)

hGSK3A/InitMet-


"A glycogen synthase kinase-3 alpha (human) that has had the initiator methionine removed. UniProtKB:P49840, 2-483." [PRO:DNx, Reactome:R-HSA-198326]


organism-modification



PR:000068970

glycogen synthase kinase-3 alpha methylated 1 (human)

hGSK3A/Me:1


"A glycogen synthase kinase-3 alpha (human) that has been methylated on the residue at the position equivalent to Cys-398 of the amino acid sequence represented by UniProtKB:P49840. UniProtKB:P49840, Cys-398, MOD:00660." [IEDB_epitope:1003847, PRO:DNx]


organism-modification



PR:000075258

glycogen synthase kinase-3 alpha deaminated 1 (human)

hGSK3A/Deam:1


"A glycogen synthase kinase-3 alpha (human) that has been deaminated on the residue at the position equivalent to Gln-227 of the amino acid sequence represented by UniProtKB:P49840. UniProtKB:P49840, Gln-227, MOD:00685." [IEDB_epitope:1584206, PRO:DNx]


organism-modification



PR:000081460

glycogen synthase kinase-3 alpha cysteinylated 1 (human)

hGSK3A/Cyst:1


"A glycogen synthase kinase-3 alpha (human) that has been cysteinylated on the residue at the position equivalent to Cys-398 of the amino acid sequence represented by UniProtKB:P49840. UniProtKB:P49840, Cys-398, MOD:00765." [IEDB_epitope:1003846, PRO:DNx]


organism-gene



PR:Q2NL51

glycogen synthase kinase-3 alpha (mouse)

mGSK3A


"A glycogen synthase kinase-3 alpha that is encoded in the genome of mouse." [OMA:Q2NL51, PRO:DNx]


organism-modification



PR:000046200

glycogen synthase kinase-3 alpha phosphorylated 1 (mouse)

mGSK3A/Phos:1


"A glycogen synthase kinase-3 alpha (mouse) that has been phosphorylated at Ser-21. UniProtKB:Q2NL51, Ser-21, MOD:00046." [iPTMnet:Q2NL51, PMID:15791206]


gene



PR:000008288

glycogen synthase kinase-3 beta

GSK3B


"A glycogen synthase kinase 3 that is a translation product of the human GSK3B gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P18266

glycogen synthase kinase-3 beta (rat)

rGSK3B


"A glycogen synthase kinase-3 beta that is encoded in the genome of rat." [OMA:P18266, PRO:DNx]


organism-sequence



PR:P18266-1

glycogen synthase kinase-3 beta isoform 1 (rat)

rGSK3B/iso:1


"A glycogen synthase kinase-3 beta isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-modification



PR:000045698

glycogen synthase kinase-3 beta phosphorylated 1 (rat)

rGSK3B/Phos:1


"A glycogen synthase kinase-3 beta (rat) that has been phosphorylated at Ser-9. UniProtKB:P18266, Ser-9, MOD:00046." [iPTMnet:P18266, PMID:11094086, PMID:12421827]


organism-gene



PR:P18431

protein kinase shaggy (fruit fly)

fly-GSK3B


"A glycogen synthase kinase-3 beta that is encoded in the genome of fruit fly." [PRO:DNx]


organism-sequence



PR:P18431-1

protein kinase shaggy isoform SGG46 (fruit fly)

fly-GSK3B/iso:SGG46


"A protein kinase shaggy (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18431-1." [PRO:DNx, UniProtKB:P18431]


organism-sequence



PR:P18431-2

protein kinase shaggy isoform Zygotic (fruit fly)

fly-GSK3B/iso:Zygotic


"A protein kinase shaggy (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18431-2." [PRO:DNx, UniProtKB:P18431]


organism-sequence



PR:P18431-3

protein kinase shaggy isoform SGG39 (fruit fly)

fly-GSK3B/iso:SGG39


"A protein kinase shaggy (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18431-3." [PRO:DNx, UniProtKB:P18431]


organism-sequence



PR:P18431-4

protein kinase shaggy isoform G (fruit fly)

fly-GSK3B/iso:G


"A protein kinase shaggy (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18431-4." [PRO:DNx, UniProtKB:P18431]


organism-gene



PR:P38615

serine/threonine-protein kinase RIM11/MSD1 (yeast)

yGSK3B


"A glycogen synthase kinase-3 beta that is encoded in the genome of yeast." [OMA:P38615, PRO:DNx]


organism-modification



PR:000046173

serine/threonine-protein kinase RIM11/MSD1 phosphorylated 1 (yeast)

yGSK3B/Phos:1


"A serine/threonine-protein kinase RIM11/MSD1 (yeast) that has been phosphorylated at Tyr-199. UniProtKB:P38615, Tyr-199, MOD:00048." [iPTMnet:P38615, PMID:10679022]


organism-gene



PR:P49841

glycogen synthase kinase-3 beta (human)

hGSK3B


"A glycogen synthase kinase-3 beta that is encoded in the genome of human." [PRO:DNx, UniProtKB:P49841]


organism-sequence



PR:P49841-1

glycogen synthase kinase-3 beta isoform 1 (human)

hGSK3B/iso:1


"A glycogen synthase kinase-3 beta isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P49841-2

glycogen synthase kinase-3 beta isoform h2 (human)

hGSK3B/iso:h2


"A glycogen synthase kinase-3 beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49841-2." [PRO:DNx, UniProtKB:P49841]


organism-modification



PR:000045809

glycogen synthase kinase-3 beta phosphorylated 1 (human)

hGSK3B/Phos:1


"A glycogen synthase kinase-3 beta (human) that has been phosphorylated on the residue at the position equivalent to Tyr-216 of the amino acid sequence represented by UniProtKB:P49841-1. Example: UniProtKB:P49841-1, Tyr-216, MOD:00048." [iPTMnet:P49841, PMID:15020233, PMID:17188038]


organism-modification



PR:000047635

glycogen synthase kinase-3 beta phosphorylated 2 (human)

hGSK3B/Phos:2


"A glycogen synthase kinase-3 beta (human) that has been phosphorylated on the residue at the position equivalent to Ser-9 of the amino acid sequence represented by UniProtKB:P49841. UniProtKB:P49841, Ser-9, MOD:00046." [PRO:DNx, Reactome:R-HSA-3149577]


organism-modification



PR:000067381

glycogen synthase kinase-3 beta cysteinylated 1 (human)

hGSK3B/Cyst:1


"A glycogen synthase kinase-3 beta (human) that has been cysteinylated on the residue at the position equivalent to Cys-317 of the amino acid sequence represented by UniProtKB:P49841-1. Example: UniProtKB:P49841-1, Cys-317, MOD:00765." [IEDB_epitope:1000222, PRO:DNx]


organism-gene



PR:Q9WV60

glycogen synthase kinase-3 beta (mouse)

mGSK3B


"A glycogen synthase kinase-3 beta that is encoded in the genome of mouse." [OMA:Q9WV60, PRO:DNx]


organism-sequence



PR:Q9WV60-1

glycogen synthase kinase-3 beta isoform 1 (mouse)

mGSK3B/iso:1


"A glycogen synthase kinase-3 beta isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-modification



PR:000046095

glycogen synthase kinase-3 beta phosphorylated 1 (mouse)

mGSK3B/Phos:1


"A glycogen synthase kinase-3 beta (mouse) that has been phosphorylated at Ser-9. UniProtKB:Q9WV60, Ser-9, MOD:00046." [iPTMnet:Q9WV60, PMID:16522636, PMID:26582204, PRO:HJD]


organism-modification



PR:000049789

glycogen synthase kinase-3 beta unphosphorylated 1 (mouse)

mGSK3B/UnPhos:1


"A glycogen synthase kinase-3 beta (mouse) that lacks phosphorylation at the position equivalent to Ser-9 of the amino acid sequence represented by UniProtKB:Q9WV60. UniProtKB:Q9WV60, Ser-9, PR:000026291." [PMID:26582204, PRO:HJD]


sequence



PR:000039611

glycogen synthase kinase-3 beta isoform 1

GSK3B/iso:1


"A glycogen synthase kinase-3 beta that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49841-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P18266-1

glycogen synthase kinase-3 beta isoform 1 (rat)

rGSK3B/iso:1


"A glycogen synthase kinase-3 beta isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P49841-1

glycogen synthase kinase-3 beta isoform 1 (human)

hGSK3B/iso:1


"A glycogen synthase kinase-3 beta isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q9WV60-1

glycogen synthase kinase-3 beta isoform 1 (mouse)

mGSK3B/iso:1


"A glycogen synthase kinase-3 beta isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:P51136

glycogen synthase kinase-3 (Dictyostelium discoideum)

Dicty-gskA


"A glycogen synthase kinase 3 that is a translation product of the gskA gene in Dictyostelium discoideum." [PRO:DAN]


organism-gene



PR:P83101

putative glycogen synthase kinase-3 homolog (fruit fly)

fly-gskt


"A glycogen synthase kinase 3 that is a translation product of the gskt gene in fruit fly." [PRO:DAN]


organism-gene



PR:Q10452

protein kinase gsk3 (Schizosaccharomyces pombe 972h-)

Spom972h-gsk3


"A glycogen synthase kinase 3 that is a translation product of the gsk3 gene in Schizosaccharomyces pombe 972h-." [PRO:DAN]


organism-gene



PR:Q9U2Q9

glycogen synthase kinase-3 (worm)

gsk-3 (worm)


"A glycogen synthase kinase 3 that is a translation product of the gsk-3 gene in worm." [PRO:DAN]


Back to top
Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0009704 de-etiolationPR:000035889 At-ASKtheta/Phos:1 PMID:20128883
GO:0009742 brassinosteroid mediated signaling pathwayPR:Q39011 At-ASK7 PMID:17873094
GO:0009910 negative regulation of flower developmentPR:000035889 At-ASKtheta/Phos:1 PMID:20128883
GO:0046777 protein autophosphorylationPR:000035898 At-ASKtheta/PhosRes- PMID:20128883
PR:000035971 At-ASK7/PhosRes- PMID:19734888
GO:0048366 leaf developmentPR:000035889 At-ASKtheta/Phos:1 PMID:20128883
GO:0048640 negative regulation of developmental growthPR:000035889 At-ASKtheta/Phos:1 PMID:20128883
GO:1900458 negative regulation of brassinosteroid mediated signaling pathwayPR:000035742 At-ASK7/Phos:1 PMID:19734888; PMID:21855796
PR:000035889 At-ASKtheta/Phos:1 PMID:20128883

Molecular Function GO Term

Protein Forms & Complexes

Evidence
GO:0004672 protein kinase activityPR:000035742 At-ASK7/Phos:1 PMID:21855796
GO:0005515 protein bindingPR:000035742 At-ASK7/Phos:1 PMID:19734888
GO:0019903 protein phosphatase bindingPR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
PR:000035742 At-ASK7/Phos:1 PMID:19734888
GO:0046827 positive regulation of protein export from nucleusPR:Q39011 At-ASK7 PMID:17873094; PMID:20387035

Cellular Location GO Term

Protein Forms & Complexes

Evidence
GO:0005634 nucleusPR:000035889 At-ASKtheta/Phos:1 PMID:20128883
PR:Q39011 At-ASK7 PMID:20387035