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Protein Ontology report - receptor-interacting serine/threonine-protein kinase 1 K63-polyubiquitinated 1
PR:000036050 - http://purl.obolibrary.org/obo/PR_000036050
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000036050   
  PRO namereceptor-interacting serine/threonine-protein kinase 1 K63-polyubiquitinated 1 
  Synonyms
PRO-Short-label: EXACT:RIPK1/K63polyUbiq:1
Other: EXACT:K-63 polyubiquitinated RIP1 | K63-linked polyUb - RIP1 | K63polyUb-RIP1 | K63polyUb-RIPK1
  Definition"A receptor-interacting serine/threonine-protein kinase 1 that has been cross-linked to K63-linked polyubiquitin. Example: UniProtKB:Q13546, Lys-377, PR:000044772." [PRO:CNA] 
  PRO Categorymodification 
  ParentPR:000014022 receptor-interacting serine/threonine-protein kinase 1
PR:000037077 ubiquitinated protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
modification


PR:000036050
receptor-interacting serine/threonine-protein kinase 1 K63-polyubiquitinated 1
RIPK1/K63polyUbiq:1
"A receptor-interacting serine/threonine-protein kinase 1 that has been cross-linked to K63-linked polyubiquitin. Example: UniProtKB:Q13546, Lys-377, PR:000044772." [PRO:CNA]

organism-modification


PR:000036051
receptor-interacting serine/threonine-protein kinase 1 K63-polyubiquitinated 1 (human)
hRIPK1/K63polyUbiq:1
"A receptor-interacting serine/threonine-protein kinase 1 K63-polyubiquitinated 1 in human. UniProtKB:Q13546, Lys-377, PR:000044772." [Reactome:R-HSA-937021]
Yes
Yes
organism-modification


PR:000036107
receptor-interacting serine/threonine-protein kinase 1 K63-polyubiquitinated 1 (mouse)
mRIPK1/K63polyUbiq:1
"A receptor-interacting serine/threonine-protein kinase 1 K63-polyubiquitinated 1 in mouse. UniProtKB:Q60855, Lys-376, PR:000044772." [PMID:17702576, PRO:CNA, PRO:DAN, PRO:KRC]

Yes
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RIPK1/K63polyUbiq:1 forms found in complexes   

RIPK1/K63polyUbiq:1 Component
 Complexes
PR:000036051 hRIPK1/K63polyUbiq:1 PR:000036049 K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human)
PR:000036053 IKK complex:K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human)
PR:000037362 K63-pUb-rip1:ticam1:activated TLR3 complex (human)
PR:000037364 IKK complex:K63-pUb-rip1:ticam1:activated TLR3 complex (human)
PR:000036107 mRIPK1/K63polyUbiq:1 PR:000036109 pel1:K63-poly-Ub-rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse)
PR:000036111 K63-poly-Ub-rip1:traf6:TAK1 kinase complex (mouse)
PR:000036114 IkappaB kinase:K63-poly-Ub-rip1:traf6:TAK1 kinase complex (mouse)
PR:000036117 pIKBK:K63-poly-Ub-rip1:traf6:TAK1 kinase complex (mouse)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036051 hRIPK1/K63polyUbiq:1
UniProtKB:Q13546, Lys-377, PR:000044772		 located_inGO:0005737 cytoplasm Reactome:REACT_26236