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Protein Ontology report - p-tbk1/p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex
PR:000036122 - http://purl.obolibrary.org/obo/PR_000036122
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000036122   
  PRO namep-tbk1/p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex 
  Synonyms
Other: RELATED:activated TLR4:TRAM:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKK epsilon
  Definition"A protein-containing complex that is composed of activated Toll-like receptor 4 (TLR4), Ticam2, Ticam1, TRAF3 linked to Lys-63 polyubiquitin, and a phosphorylated kinase either tbk1 or IKKE." [Reactome:R-HSA-936970] 
  CommentRequested by=TLR. 
  PRO Categorycomplex 
  ParentG0032991 protein-containing complex
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Complex1                                                  Organism-Complex 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
complex


PR:000036122
p-tbk1/p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex
mCHUK/iso:1/Phos:1
"A protein-containing complex that is composed of activated Toll-like receptor 4 (TLR4), Ticam2, Ticam1, TRAF3 linked to Lys-63 polyubiquitin, and a phosphorylated kinase either tbk1 or IKKE." [Reactome:R-HSA-936970]

organism-complex


PR:000036123
p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human)
mCHUK/iso:1/Phos:1
"A p-tbk1/p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex in human in which the phosphorylated kinase component is TBK1." [Reactome:R-HSA-936970]
Yes
organism-complex


PR:000036124
p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human)
mCHUK/iso:1/Phos:1
"A p-tbk1/p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex in human in which the phosphorylated kinase component is IKKE." [Reactome:R-HSA-936970]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036123 mCHUK/iso:1/Phos:1 acts_upstream_of_or_withinGO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809
located_inGO:0010008 endosome membrane Reactome:REACT_26959
PR:000036124 mCHUK/iso:1/Phos:1 acts_upstream_of_or_withinGO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809
located_inGO:0010008 endosome membrane Reactome:REACT_26959