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Protein Ontology report - free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:activated TLR3/TLR4 complex (human)
PR:000036189 -
http://purl.obolibrary.org/obo/PR_000036189
Protein Forms
Annotations
Ontology Information
Show OBO stanza
/
GPI
PRO ID
PR:000036189
PRO name
free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:activated TLR3/TLR4 complex (human)
Definition
"A protein-containing complex in human that is composed of unanchored K63-linked polyubiquitin, the components of the tak 1 complex (tak1 and tab proteins), polyubiquitinated traf6, ticam1 and either activated Toll-like receptor 3 (TLR3) or activated Toll-like receptor 4 (TLR4) with ticam2." [PRO:DAN,
Reactome:R-HSA-936954
]
PRO Category
organism-complex
Parent
G0032991
protein-containing complex
Taxon
NCBITaxon:9606
Homo sapiens
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Complex
0
Organism-Complex
3
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
comp.
In Complex?
organism-complex
PR:000036189
free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:activated TLR3/TLR4 complex (human)
hACTB/Ac:1
"A protein-containing complex in human that is composed of unanchored K63-linked polyubiquitin, the components of the tak 1 complex (tak1 and tab proteins), polyubiquitinated traf6, ticam1 and either activated Toll-like receptor 3 (TLR3) or activated Toll-like receptor 4 (TLR4) with ticam2." [PRO:DAN, Reactome:R-HSA-936954]
organism-complex
PR:000035734
free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
hK63polyUbiq
"A free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex whose components are encoded in the genome of human." [Reactome:R-HSA-936954]
organism-complex
PR:000037342
free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:activated TLR3 complex (human)
Spom-(cdc13:cdk1)
"A free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:activated TLR3 complex whose components are encoded in the genome of human." [PMID:12609980, PMID:16115877, PRO:VS, Reactome:R-HSA-936954]
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000035734
hK63polyUbiq
acts_upstream_of_or_within
GO:0002756
MyD88-independent toll-like receptor signaling pathway
Reactome:REACT_6809
enables
GO:0004674
protein serine/threonine kinase activity
Reactome:REACT_26036
located_in
GO:0010008
endosome membrane
Reactome:REACT_26036
PR:000037342
Spom-(cdc13:cdk1)
acts_upstream_of_or_within
GO:0002756
MyD88-independent toll-like receptor signaling pathway
Reactome:REACT_6783
GO:0034138
toll-like receptor 3 signaling pathway
Reactome:REACT_6783
located_in
GO:0010008
endosome membrane
Reactome:REACT_6783