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Protein Ontology report - trypsin, signal peptide removed form
PR:000036291 - http://purl.obolibrary.org/obo/PR_000036291
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000036291   
  PRO nametrypsin, signal peptide removed form 
  Synonyms
PRO-Short-label: EXACT:PRSS/SigPep-
Other: EXACT:trypsinogen
  Definition"A trypsin that has had the signal peptide removed." [PRO:DAN] 
  PRO Categorymodification 
  ParentPR:000027795 trypsin
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification32                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
modification



PR:000036291

trypsin, signal peptide removed form

PRSS/SigPep-


"A trypsin that has had the signal peptide removed." [PRO:DAN]


modification



PR:000018779

prostate-specific antigen, signal peptide removed form

KLK3/SigPep-


"A prostate-specific antigen that has had the signal peptide removed." [PRO:DNx]


modification



PR:000025453

prostate-specific antigen isoform 1, signal peptide removed form

KLK3/iso:1/SigPep-


"A prostate-specific antigen isoform 1 that has had the signal peptide removed." [PRO:DAN]


modification



PR:000003018

prostate-specific antigen isoform 1 cleaved and glycosylated form

KLK3/iso:1/ClvGlyco+


"A prostate-specific antigen isoform 1, signal peptide removed form that has had the propeptide removed and that includes at least one glycosylated residue." [PRO:CNA]


modification



PR:000003019

prostate-specific antigen isoform 1 cleaved and N-glycosylated 1

KLK3/iso:1/ClvNGlyco:1


"A prostate-specific antigen isoform 1 cleaved and glycosylated form that contains an N-glycosylated Asn residue within the glycosylation consensus sequence near its N terminus. Example: UniProtKB:P07288-1, 25-261, Asn-69, MOD:00160." [PMID:2422647, PMID:3691515, PRO:CNA, PRO:DAN]


modification



PR:000018822

granzyme D, signal peptide removed form

Gzmd/SigPep-


"A granzyme D that has had the signal peptide removed." [PRO:DNx]


modification



PR:000026635

granzyme D isoform 1, signal peptide removed form

Gzmd/iso:1/SigPep-


"A granzyme D isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000018825

granzyme G, signal peptide removed form

Gzmg/SigPep-


"A granzyme G that has had the signal peptide removed." [PRO:DNx]


modification



PR:000026722

granzyme G isoform 1, signal peptide removed form

Gzmg/iso:1/SigPep-


"A granzyme G isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000018828

granzyme E, signal peptide removed form

Gzme/SigPep-


"A granzyme E that has had the signal peptide removed." [PRO:DNx]


modification



PR:000026595

granzyme E isoform 1, signal peptide removed form

Gzme/iso:1/SigPep-


"A granzyme E isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000018831

granzyme C, signal peptide removed form

Gzmc/SigPep-


"A granzyme C that has had the signal peptide removed." [PRO:DNx]


modification



PR:000026721

granzyme C isoform 1, signal peptide removed form

Gzmc/iso:1/SigPep-


"A granzyme C isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000018834

granzyme H, signal peptide removed form

GZMH/SigPep-


"A granzyme H that has had the signal peptide removed." [PRO:DNx]


modification



PR:000026717

granzyme H isoform 1, signal peptide removed form

GZMH/iso:1/SigPep-


"A granzyme H isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000018837

granzyme F, signal peptide removed form

Gzmf/SigPep-


"A granzyme F that has had the signal peptide removed." [PRO:DNx]


modification



PR:000026685

granzyme F isoform 1, signal peptide removed form

Gzmf/iso:1/SigPep-


"A granzyme F isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000019097

azurocidin, signal peptide removed form

AZU1/SigPep-


"An azurocidin that has had the signal peptide removed." [PRO:DNx]


modification



PR:000019381

chymase, signal peptide removed form

CMA1/SigPep-


"A chymase that has had the signal peptide removed." [PRO:DNx]


modification



PR:000019548

chymotrypsinogen B, signal peptide removed form

CTRB1/SigPep-


"A chymotrypsinogen B that has had the signal peptide removed." [PRO:DNx]


modification



PR:000019775

chymotrypsin-like elastase family member 2A, signal peptide removed form

ELA2A/SigPep-


"A chymotrypsin-like elastase family member 2A that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000037244

chymotrypsin-like elastase family member 2A, pro-form (mouse)

mCELA2A/pro


"A chymotrypsin-like elastase family member 2A, signal peptide removed form in mouse. UniProtKB:P05208, 17-271." [PMID:20179351, PRO:KRC]


organism-modification



PR:000037245

chymotrypsin-like elastase family member 2A, mature form (mouse)

mCELA2A/mature


"A chymotrypsin-like elastase family member 2A, pro-form (mouse) that has had the activation peptide removed by proteolytic cleavage. UniProtKB:P05208, 31-271." [PMID:20179351, PMID:3641189, PRO:KRC]

Yes

modification



PR:000019778

chymotrypsin-like elastase family member 2B, signal peptide removed form

ELA2B/SigPep-


"A chymotrypsin-like elastase family member 2B that has had the signal peptide removed." [PRO:DNx]


modification



PR:000020385

kallikrein-14, signal peptide removed form

KLK14/SigPep-


"A kallikrein-14 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000020388

kallikrein-7, signal peptide removed form

KLK7/SigPep-


"A kallikrein-7 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000021125

serine protease 1, signal peptide removed form

PRSS1/SigPep-


"A serine protease 1 that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000048939

serine protease 1, signal peptide removed form (human)

hPRSS1/SigPep-


"A serine protease 1 (human) that has had the signal peptide removed. UniProtKB:P07477, 16-247." [PRO:DNx, Reactome:R-HSA-5693354]


modification



PR:000021131

myeloblastin, signal peptide removed form

PRTN3/SigPep-


"A myeloblastin that has had the signal peptide removed." [PRO:DNx]


modification



PR:000021729

tryptase beta-2, signal peptide removed form

TPSB2/SigPep-


"A tryptase beta-2 that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000050080

tryptase beta-2, mature form (human)

hTPSB2/mature


"A tryptase beta-2 (human) that has had the signal peptide and propeptide removed. UniProtKB:P20231, 31-275." [PRO:DNx, UniProtKB:P20231]


modification



PR:000026632

granzyme A, signal peptide removed form

GZMA/SigPep-


"A granzyme A that has had the signal peptide removed." [PRO:DNx]


modification



PR:000026633

granzyme A isoform 1, signal peptide removed form

GZMA/iso:1/SigPep-


"A granzyme A isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000026712

granzyme B, signal peptide removed form

GZMB/SigPep-


"A granzyme B that has had the signal peptide removed." [PRO:DNx]


modification



PR:000026713

granzyme B isoform 1, signal peptide removed form

GZMB/iso:1/SigPep-


"A granzyme B isoform 1 that has had the signal peptide removed." [PRO:DNx]


modification



PR:000028941

activated trypsin

PRSS/ProPep-


"A trypsin, signal peptide removed form that has been activated by removal of the propeptide (activation peptide)." [PRO:DAN]


modification



PR:000003018

prostate-specific antigen isoform 1 cleaved and glycosylated form

KLK3/iso:1/ClvGlyco+


"A prostate-specific antigen isoform 1, signal peptide removed form that has had the propeptide removed and that includes at least one glycosylated residue." [PRO:CNA]


modification



PR:000003019

prostate-specific antigen isoform 1 cleaved and N-glycosylated 1

KLK3/iso:1/ClvNGlyco:1


"A prostate-specific antigen isoform 1 cleaved and glycosylated form that contains an N-glycosylated Asn residue within the glycosylation consensus sequence near its N terminus. Example: UniProtKB:P07288-1, 25-261, Asn-69, MOD:00160." [PMID:2422647, PMID:3691515, PRO:CNA, PRO:DAN]


organism-modification



PR:000037245

chymotrypsin-like elastase family member 2A, mature form (mouse)

mCELA2A/mature


"A chymotrypsin-like elastase family member 2A, pro-form (mouse) that has had the activation peptide removed by proteolytic cleavage. UniProtKB:P05208, 31-271." [PMID:20179351, PMID:3641189, PRO:KRC]

Yes

organism-modification



PR:000050073

tryptase alpha/beta-1, mature form (human)

hTPSAB1/mature


"A tryptase alpha/beta-1 (human) that has had the signal peptide and propeptide removed. Example: UniProtKB:Q15661-1, 31-275." [PRO:DNx, UniProtKB:Q15661]


organism-modification



PR:000050080

tryptase beta-2, mature form (human)

hTPSB2/mature


"A tryptase beta-2 (human) that has had the signal peptide and propeptide removed. UniProtKB:P20231, 31-275." [PRO:DNx, UniProtKB:P20231]


organism-modification



PR:000059609

chymotrypsin-C isoform 1 active form (mouse)

mCTRC/iso:1/active


"A chymotrypsin-C isoform 1 (mouse) that has had the signal peptide and the propeptide removed. Propeptide (aka activation peptide) cleavage is mediated by trypsin, and yields the mature active form. UniProtKB:Q3SYP2-1, 30-268." [PRO:KRC]


organism-modification



PR:000059630

chymotrypsin-C isoform 1 inactive form (mouse)

mCTRC/iso:1/inactive


"A chymotrypsin-C isoform 1 (mouse) that has had the signal peptide removed but retains the propeptide. Propeptide (aka activation peptide) removal is required for activation, hence this form is inactive. UniProtKB:Q3SYP2-1, 17-268." [PRO:DAN, PRO:KRC]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000037245 mCELA2A/mature
UniProtKB:P05208, 31-271
acts_upstream_of_or_withinGO:0006508 proteolysis MGI_ref:4440399; PMID:20179351
GO:0061436 establishment of skin barrier MGI_ref:4440399; PMID:20179351
enablesGO:0017171 serine hydrolase activity MGI_ref:4440399; PMID:20179351
GO:0017171 serine hydrolase activity MGI_ref:4440399; PMID:20179351