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RACE-PRO
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Documentation
Protein Ontology report - NS4B
PR:000036833 -
http://purl.obolibrary.org/obo/PR_000036833
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000036833
PRO name
NS4B
Synonyms
PRO-Short-label
:
EXACT:
DenV-NS4B
Other
:
EXACT:
Non-structural protein 4B
Definition
"A dengue virus genome polyprotein proteolytic cleavage product that is a highly hydrophobic transmembrane non-structural protein encoded by the dengue virus RNA genome which is, in part, responsible for the membrane arrangements leading to the formation of the viral replication complex." [
PMID:22772157
, PRO:ES]
Comment
Requested by=IDODEN.
PRO Category
modification
Parent
PR:000036818
dengue virus genome polyprotein proteolytic cleavage product
PR:000036832
precursor of NS4B
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
comp.
In Complex?
modification
PR:000036833
NS4B
DenV-NS4B
"A dengue virus genome polyprotein proteolytic cleavage product that is a highly hydrophobic transmembrane non-structural protein encoded by the dengue virus RNA genome which is, in part, responsible for the membrane arrangements leading to the formation of the viral replication complex." [PMID:22772157, PRO:ES]
organism-modification
PR:000044766
NS4B (Dengue virus 2 Thailand/NGS-C/1944)
NS4B (DEN2N)
"An NS4B in Dengue virus 2 Thailand/NGS-C/1944. UniProtKB:P14340, 2244-2491." [PRO:DNx]
Yes
organism-modification
PR:000044767
NS4B (Dengue virus 2 Thailand/16681/84)
NS4B (DEN26)
"An NS4B in Dengue virus 2 Thailand/16681/84. UniProtKB:P29990, 2244-2491." [PRO:DNx]
Yes
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000044766
NS4B (DEN2N)
UniProtKB:P14340, 2244-2491
acts_upstream_of_or_within
GO:0019079
viral genome replication
PMID:21810535
located_in
GO:0019034
viral replication complex
PMID:21810535
PR:000044767
NS4B (DEN26)
UniProtKB:P29990, 2244-2491
acts_upstream_of_or_within
GO:0039563
symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT1 activity
PMID:14612562
