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Protein Ontology report - NS4B
PR:000036833 - http://purl.obolibrary.org/obo/PR_000036833
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000036833   
  PRO nameNS4B 
  Synonyms
PRO-Short-label: EXACT:DenV-NS4B
Other: EXACT:Non-structural protein 4B
  Definition"A dengue virus genome polyprotein proteolytic cleavage product that is a highly hydrophobic transmembrane non-structural protein encoded by the dengue virus RNA genome which is, in part, responsible for the membrane arrangements leading to the formation of the viral replication complex." [PMID:22772157, PRO:ES] 
  CommentRequested by=IDODEN. 
  PRO Categorymodification 
  ParentPR:000036818 dengue virus genome polyprotein proteolytic cleavage product
PR:000036832 precursor of NS4B
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Short Name

Ann. Has Annotation?

comp. In Complex?
modification



PR:000036833 NS4B

DenV-NS4B


organism-modification



PR:000044766 NS4B (Dengue virus 2 Thailand/NGS-C/1944)

NS4B (DEN2N)

Yes

organism-modification



PR:000044767 NS4B (Dengue virus 2 Thailand/16681/84)

NS4B (DEN26)

Yes

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0019079 viral genome replicationPR:000044766 NS4B (DEN2N) PMID:21810535
GO:0039563 symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT1 activityPR:000044767 NS4B (DEN26) PMID:14612562

Cellular Location GO Term

Protein Forms & Complexes

Evidence
GO:0019034 viral replication complexPR:000044766 NS4B (DEN2N) PMID:21810535