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PRO ID
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PRO name | chymotrypsin-like elastase family member 2A, mature form (mouse) |
Synonyms | PRO-Short-label: | EXACT: | mCELA2A/mature | PRO-proteoform-std: | EXACT: | UniProtKB:P05208, 31-271 | PRO-proteoform-ftid: | EXACT: | PRO_0000027688 | Other: | RELATED: | Cela2a (mouse) | Ela2 (mouse) | elastase 2 (mouse) | |
Definition | "A chymotrypsin-like elastase family member 2A, pro-form (mouse) that has had the activation peptide removed by proteolytic cleavage. UniProtKB:P05208, 31-271." [PMID:20179351, PMID:3641189, PRO:KRC] |
Comment | Note: Figure 3C in PMID:20179351 shows the Western blot analysis of WT and Tg-ELA2 (Tg) epidermal and dermal extracts, using an anti-FLAG antibody, revealing exogenous ELA2flag as pro-forms and active forms in the epidermis of transgenic animals. Figure 1 in PMID:3641189 shows sequence of mRNA corresponding to preproenzyme and presumes start site of active enzyme based on homology with porcine enzyme. |
PRO Category | organism-modification |
Parent | PR:000028941 activated trypsin PR:000037244 chymotrypsin-like elastase family member 2A, pro-form (mouse)
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Taxon | NCBITaxon:10090 Mus musculus |
Term Hierarchy Visualization |
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