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Protein Ontology report - sonic hedgehog protein N-product dually lipidated 1 (mouse)
PR:000037269 -
http://purl.obolibrary.org/obo/PR_000037269
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:000037269
PRO name
sonic hedgehog protein N-product dually lipidated 1 (mouse)
Synonyms
PRO-Short-label
:
EXACT:
mSHH/Clv:Nter/2*Lipid:1
PRO-proteoform-std
:
EXACT:
UniProtKB:Q62226
, 25-198, Cys-25,
MOD:00069
|Gly-198,
MOD:00314
Definition
"A sonic hedgehog protein N-product in mouse that has been further modified on the N-terminal Cys residue by palmitoylation and the C-terminal Gly residue by cholesterylation.
UniProtKB:Q62226
, 25-198, Cys-25,
MOD:00069
|Gly-198,
MOD:00314
." [
PMID:15075292
,
PMID:8824192
, PRO:KRC]
PRO Category
organism-modification
Parent
PR:000037272
sonic hedgehog protein, signal peptide removed form (mouse)
PR:000037273
sonic hedgehog protein N-product
Taxon
NCBITaxon:10090
Mus musculus
Term Hierarchy
Visualization
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Functional Annotation (PRO-centric view)
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PRO Term
GO Annotation
Evidence
PR:000037269
mSHH/Clv:Nter/2*Lipid:1
UniProtKB:Q62226, 25-198, Cys-25, MOD:00069|Gly-198, MOD:00314
acts_upstream_of_or_within
GO:0007224
smoothened signaling pathway
MGI_ref:3039193;
PMID:15075292
GO:0009952
anterior/posterior pattern specification
MGI_ref:2135419;
PMID:11389830
GO:0030326
embryonic limb morphogenesis
MGI_ref:2135419;
PMID:11389830
GO:0042733
embryonic digit morphogenesis
MGI_ref:3039193;
PMID:15075292