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Protein Ontology report - cochlin proteolytic cleavage product
PR:000037270 -
http://purl.obolibrary.org/obo/PR_000037270
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000037270
PRO name
cochlin proteolytic cleavage product
Synonyms
PRO-Short-label
:
EXACT:
COCH/ClvPrd
Definition
"A cochlin that has been processed by proteolytic cleavage." [PRO:CNA, PRO:DAN]
PRO Category
modification
Parent
PR:000005683
cochlin
PR:000018264
proteolytic cleavage product
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
3
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
comp.
In Complex?
modification
PR:000037270
cochlin proteolytic cleavage product
COCH/ClvPrd
"A cochlin that has been processed by proteolytic cleavage." [PRO:CNA, PRO:DAN]
organism-modification
PR:000037261
cochlin p8 (mouse)
mCOCH/Clv:p8
"A cochlin, signal peptide removed form (mouse) that results from cleavage downstream of the LCCL domain (Pfam:PF03815) by aggrecanases proteolytic activity. This form results from the deglycosylation of the N-terminal fragment p18. UniProtKB:Q62507, 26-134." [PMID:23684986, PRO:KRC]
Yes
organism-modification
PR:000037262
cochlin p18 (mouse)
mCOCH/Clv:p18
"A cochlin, signal peptide removed form (mouse) that results from cleavage downstream of the LCCL domain (Pfam:PF03815), and includes at least one glycosylated residue. UniProtKB:Q62507, 26-134, MOD:00693." [PMID:23684986, PRO:KRC]
Yes
organism-modification
PR:000037263
cochlin p40 (mouse)
mCOCH/Clv:p40
"A cochlin, signal peptide removed form (mouse) that results from further cleavage of the LCCL domain (Pfam:PF03815) after aggrecanases proteolytic activity. UniProtKB:Q62507, 135-552." [PMID:23684986, PRO:KRC]
Yes
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000037261
mCOCH/Clv:p8
UniProtKB:Q62507, 26-134
located_in
GO:0005576
extracellular region
MGI_ref:5525040;
PMID:23684986
PR:000037262
mCOCH/Clv:p18
UniProtKB:Q62507, 26-134, MOD:00693
located_in
GO:0005576
extracellular region
MGI_ref:5525040;
PMID:23684986
PR:000037263
mCOCH/Clv:p40
UniProtKB:Q62507, 135-552
located_in
GO:0031012
extracellular matrix
MGI_ref:5525040;
PMID:23684986
