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Protein Ontology report - sonic hedgehog protein N-product
PR:000037273 -
http://purl.obolibrary.org/obo/PR_000037273
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000037273
PRO name
sonic hedgehog protein N-product
Synonyms
PRO-Short-label
:
EXACT:
SHH/Clv:Nter
Other
:
EXACT:
SHH-N
Definition
"A sonic hedgehog protein, signal peptide removed form that is the N-terminal product after autolysis. The N-product is the active species in signal transduction." [PRO:CNA]
PRO Category
modification
Parent
PR:000021467
sonic hedgehog protein, signal peptide removed form
PR:000021468
sonic hedgehog protein proteolytic cleavage product
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Modification
1
Organism-Modification
2
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Short Name
Ann.
Has Annotation?
comp.
In Complex?
modification
PR:000037273
sonic hedgehog protein N-product
SHH/Clv:Nter
organism-modification
PR:000037269
sonic hedgehog protein N-product dually lipidated 1 (mouse)
mSHH/Clv:Nter/2*Lipid:1
Yes
organism-modification
PR:000037274
sonic hedgehog protein N-product dually lipidated 1 (human)
hSHH/Clv:Nter/2*Lipid:1
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000037269
mSHH/Clv:Nter/2*Lipid:1
UniProtKB:Q62226, 25-198, Cys-25, MOD:00069|Gly-198, MOD:00314
acts_upstream_of_or_within
GO:0007224
smoothened signaling pathway
MGI_ref:3039193;
PMID:15075292
GO:0009952
anterior/posterior pattern specification
MGI_ref:2135419;
PMID:11389830
GO:0030326
embryonic limb morphogenesis
MGI_ref:2135419;
PMID:11389830
GO:0042733
embryonic digit morphogenesis
MGI_ref:3039193;
PMID:15075292
