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Protein Ontology report - Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1
PR:000037352 - http://purl.obolibrary.org/obo/PR_000037352
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000037352   
  PRO nameArf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1 
  Synonyms
PRO-Short-label: EXACT:ARAP3/iso:1
Other: EXACT:ARAP3 isoform 1
  Definition"An Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8R5G7-1 or a 1:1 ortholog thereof." [PMID:15546919, PRO:HJD] 
  PRO Categorysequence 
  ParentPR:000004195 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
sequence


PR:000037352
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1
ARAP3/iso:1
"An Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8R5G7-1 or a 1:1 ortholog thereof." [PMID:15546919, PRO:HJD]

organism-sequence


PR:Q8R5G7-1
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1 (mouse)
mARAP3/iso:1
"An Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1 that is encoded in the genome of mouse." [PMID:15546919, PRO:HJD]
Yes
organism-sequence


PR:Q8WWN8-1
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1 (human)
hARAP3/iso:1
"An Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 isoform 1 that is encoded in the genome of human." [PMID:11804589, PRO:CNA, UniProtKB:Q8WWN8]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q8R5G7-1 mARAP3/iso:1 acts_upstream_of_or_withinGO:0008360 regulation of cell shape MGI_ref:3511766; PMID:15546919
GO:0030336 negative regulation of cell migration MGI_ref:3511766; PMID:15546919
GO:0035021 negative regulation of Rac protein signal transduction MGI_ref:3511766; PMID:15546919
GO:0035024 negative regulation of Rho protein signal transduction MGI_ref:3511766; PMID:15546919
located_inGO:0001726 ruffle MGI_ref:3511766; PMID:15546919
GO:0005737 cytoplasm MGI_ref:3511766; PMID:15546919
GO:0030027 lamellipodium MGI_ref:3511766; PMID:15546919