Protein Ontology

Home

Linked Open Data

Browse

Statistics

Download

RACE-PRO

PRO tracker

Community

PRO Consortium

Publications

Documentation

Protein Ontology report - IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex

PR:000037353 - http://purl.obolibrary.org/obo/PR_000037353

Protein Forms

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000037353

PRO name

IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex

Synonyms

Reactome-displayName:

activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKKE:IRF3

Definition

"A protein-containing complex that is composed of activated Toll-like receptor 3 (TLR3), Ticam1 (TRIF), TRAF3 linked to Lys-63 polyubiquitin, phosphorylated TBK1 and IRF3 unphosphorylated." [PMID:14517278, PMID:14739303, PMID:16281057]

Comment

Requested by=TLR.

PRO Category

complex

Parent

G0032991 protein-containing complex

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Complex	1	Organism-Complex	1

Term Hierarchy
Visualization

DAG:

OLS:

Back to top

Protein Forms

Switch to Extended View

Category

PRO Form Name

Short Name

Ann. Has Annotation?

comp. In Complex?

complex

PR:000037353 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex

ARAP3/iso:1

organism-complex

PR:000037354 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human)

ARAP3/iso:1

Yes

Back to top

Functional Annotation (GO-centric view)

Switch to PRO Centric View

Biological Process GO Term	Protein Forms & Complexes	Evidence
GO:0002756 MyD88-independent toll-like receptor signaling pathway	PR:000037354 ARAP3/iso:1	Reactome:REACT_6783
GO:0034138 toll-like receptor 3 signaling pathway	PR:000037354 ARAP3/iso:1	Reactome:REACT_6783
Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0010008 endosome membrane	PR:000037354 ARAP3/iso:1	Reactome:REACT_6783