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Protein Ontology report - K63-pUb-rip1:ticam1:activated TLR3 complex
PR:000037361 -
http://purl.obolibrary.org/obo/PR_000037361
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000037361
PRO name
K63-pUb-rip1:ticam1:activated TLR3 complex
Synonyms
Other
:
RELATED:
activated TLR3:TRIF:K63-pUb-RIP1
Definition
"A protein-containing complex that is composed of activated Toll-like receptor 3 (TLR3), Ticam1 (TRIF), and the death receptor RIPK1 (RIP1) cross-linked to K63-linked polyubiquitin." [
PMID:15064760
,
PMID:15814722
,
PMID:16115877
, PRO:VS,
Reactome:R-HSA-937016
]
Comment
Requested by=TLR.
PRO Category
complex
Parent
G0032991
protein-containing complex
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Complex
1
Organism-Complex
1
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
comp.
In Complex?
complex
PR:000037361
K63-pUb-rip1:ticam1:activated TLR3 complex
ARAP3/iso:1
"A protein-containing complex that is composed of activated Toll-like receptor 3 (TLR3), Ticam1 (TRIF), and the death receptor RIPK1 (RIP1) cross-linked to K63-linked polyubiquitin." [PMID:15064760, PMID:15814722, PMID:16115877, PRO:VS, Reactome:R-HSA-937016]
organism-complex
PR:000037362
K63-pUb-rip1:ticam1:activated TLR3 complex (human)
ARAP3/iso:1
"A K63-pUb-rip1:ticam1:activated TLR3 complex whose components are encoded in the genome of human." [PMID:15064760, PMID:15814722, PMID:16115877, PRO:VS, Reactome:R-HSA-937016]
Yes
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000037362
ARAP3/iso:1
acts_upstream_of_or_within
GO:0002756
MyD88-independent toll-like receptor signaling pathway
Reactome:REACT_6783
GO:0034138
toll-like receptor 3 signaling pathway
Reactome:REACT_6783
located_in
GO:0010008
endosome membrane
Reactome:REACT_6783
