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Protein Ontology report - D(2) dopamine receptor isoform 1
PR:000037412 - http://purl.obolibrary.org/obo/PR_000037412
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000037412   
  PRO nameD(2) dopamine receptor isoform 1 
  Synonyms
PRO-Short-label: EXACT:DRD2/iso:1
Other: EXACT:D(2) dopamine receptor long form | D2(Long) | D2L
  Definition"A D(2) dopamine receptor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61168-1 or a 1:1 ortholog thereof." [PRO:KRC] 
  PRO Categorysequence 
  ParentPR:000001177 D(2) dopamine receptor
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
sequence


PR:000037412
D(2) dopamine receptor isoform 1
DRD2/iso:1
"A D(2) dopamine receptor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61168-1 or a 1:1 ortholog thereof." [PRO:KRC]

organism-sequence


PR:P14416-1
D(2) dopamine receptor isoform 1 (human)
hDRD2/iso:1
"A D(2) dopamine receptor isoform 1 that is encoded in the genome of human." [PRO:CNA]

organism-sequence


PR:P61168-1
D(2) dopamine receptor isoform 1 (mouse)
mDRD2/iso:1
"A D(2) dopamine receptor isoform 1 that is encoded in the genome of mouse." [PMID:1991517, PRO:KRC]
Yes
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathwayPR:P61168-1 mDRD2/iso:1 MGI_ref:893272; PMID:7706278
PR:P61168-1 mDRD2/iso:1 MGI_ref:893272; PMID:7706278
GO:0007212 dopamine receptor signaling pathwayPR:P61168-1 mDRD2/iso:1 MGI_ref:2181304; PMID:11089973
GO:0007626 locomotory behaviorPR:P61168-1 mDRD2/iso:1 MGI_ref:1927281; PMID:11069937
GO:0032228 regulation of synaptic transmission, GABAergicPR:P61168-1 mDRD2/iso:1 MGI_ref:3628700; PMID:15489038
GO:0060134 prepulse inhibitionPR:P61168-1 mDRD2/iso:1 MGI_ref:3611062; PMID:12476322

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/GoPR:P61168-1 mDRD2/iso:1 MGI_ref:893272; PMID:7706278
PR:P61168-1 mDRD2/iso:1 MGI_ref:893272; PMID:7706278
PR:P61168-1 mDRD2/iso:1 MGI_ref:893272; PMID:7706278
PR:P61168-1 mDRD2/iso:1 MGI_ref:893272; PMID:7706278

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0016020 membranePR:P61168-1 mDRD2/iso:1 MGI_ref:893272; PMID:7706278