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Protein Ontology report - D(2) dopamine receptor isoform 2
PR:000037413 - http://purl.obolibrary.org/obo/PR_000037413
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000037413   
  PRO nameD(2) dopamine receptor isoform 2 
  Synonyms
PRO-Short-label: EXACT:DRD2/iso:2
Other: EXACT:D(2) dopamine receptor short form | D2(Short) | D2S
  Definition"A D(2) dopamine receptor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P61168-2 or a 1:1 ortholog thereof." [PMID:11069937, PMID:1991517, PRO:KRC] 
  PRO Categorysequence 
  ParentPR:000001177 D(2) dopamine receptor
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
sequence


PR:000037413 D(2) dopamine receptor isoform 2
DRD2/iso:2

organism-sequence


PR:P14416-2 D(2) dopamine receptor isoform 2 (human)
hDRD2/iso:2

organism-sequence


PR:P61168-2 D(2) dopamine receptor isoform 2 (mouse)
mDRD2/iso:2
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P61168-2 mDRD2/iso:2 acts_upstream_of_or_withinGO:0001975 response to amphetamine MGI_ref:3611062; PMID:12476322
GO:0014059 regulation of dopamine secretion MGI_ref:3655899; PMID:11943831
GO:0032228 regulation of synaptic transmission, GABAergic MGI_ref:3628700; PMID:15489038
GO:0042220 response to cocaine MGI_ref:3655899; PMID:11943831
GO:0043278 response to morphine MGI_ref:3655899; PMID:11943831
GO:0051967 negative regulation of synaptic transmission, glutamatergic MGI_ref:3628700; PMID:15489038
GO:0060160 negative regulation of dopamine receptor signaling pathway MGI_ref:2181304; PMID:11089973
enablesGO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go MGI_ref:892768; PMID:1991517
GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go MGI_ref:892768; PMID:1991517