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Documentation
Protein Ontology report - activated TLR4 complex (chicken)
PR:000037474 -
http://purl.obolibrary.org/obo/PR_000037474
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:000037474
PRO name
activated TLR4 complex (chicken)
Synonyms
PRO-Short-label
:
EXACT:
chick-TLR4actv
Other
:
EXACT:
chick-(LY96:LPS:TLR4) | LY96:LPS:TLR4 complex (chicken) | MD2:LPS:TLR4 (chicken)
Definition
"An activated TLR4 complex whose components are encoded in the genome of chicken. LPS binding to Toll-like receptor 4 results in dimerization of the TLR4 associated with MD2." [
PMID:18768894
,
PMID:24034933
,
Reactome:R
-GGA-433789]
Comment
Requested by=TLR.
PRO Category
organism-complex
Parent
PR:000036076
activated TLR4 complex
Taxon
NCBITaxon:9031
Gallus gallus
Term Hierarchy
Visualization
DAG:
OLS:
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Functional Annotation (GO-centric view)
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PRO Centric View
Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0034142
toll-like receptor 4 signaling pathway
PR:000037474
chick-TLR4actv
PMID:18768894
GO:0045429
positive regulation of nitric oxide biosynthetic process
PR:000037474
chick-TLR4actv
PMID:24034933
GO:0051607
defense response to virus
PR:000037474
chick-TLR4actv
PMID:24034933
Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005886
plasma membrane
PR:000037474
chick-TLR4actv
Reactome:REACT_25442