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Protein Ontology report - lysosomal cobalamin transport escort protein LMBD1 isoform 1
PR:000037483 - http://purl.obolibrary.org/obo/PR_000037483
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000037483   
  PRO namelysosomal cobalamin transport escort protein LMBD1 isoform 1 
  Synonyms
PRO-Short-label: EXACT:LMBRD1/iso:1
  Definition"A lysosomal cobalamin transport escort protein LMBD1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8K0B2-1 or a 1:1 ortholog thereof." [PMID:16141072, PRO:HJD] 
  PRO Categorysequence 
  ParentPR:000032677 lysosomal cobalamin transport escort protein LMBD1
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Short Name

Ann. Has Annotation?

comp. In Complex?
sequence



PR:000037483 lysosomal cobalamin transport escort protein LMBD1 isoform 1

LMBRD1/iso:1


organism-sequence



PR:Q6AZ61-1 lysosomal cobalamin transport escort protein LMBD1 isoform 1 (rat)

rLMBRD1/iso:1


organism-sequence



PR:Q8K0B2-1 lysosomal cobalamin transport escort protein LMBD1 isoform 1 (mouse)

mLMBRD1/iso:1

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q8K0B2-1 mLMBRD1/iso:1 acts_upstream_of_or_withinGO:0038016 insulin receptor internalization MGI_ref:5543853; PMID:24078630
NOT GO:0043408 regulation of MAPK cascade MGI_ref:5543853; PMID:24078630
GO:0046325 negative regulation of glucose import MGI_ref:5543853; PMID:24078630
GO:0046627 negative regulation of insulin receptor signaling pathway MGI_ref:5543853; PMID:24078630
GO:0051898 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction MGI_ref:5543853; PMID:24078630