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Protein Ontology report - lysosomal cobalamin transport escort protein LMBD1 isoform 1
PR:000037483 -
http://purl.obolibrary.org/obo/PR_000037483
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000037483
PRO name
lysosomal cobalamin transport escort protein LMBD1 isoform 1
Synonyms
PRO-Short-label
:
EXACT:
LMBRD1/iso:1
Definition
"A lysosomal cobalamin transport escort protein LMBD1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:Q8K0B2-1
or a 1:1 ortholog thereof." [
PMID:16141072
, PRO:HJD]
PRO Category
sequence
Parent
PR:000032677
lysosomal cobalamin transport escort protein LMBD1
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
2
Modification
0
Organism-Modification
0
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Short Name
Ann.
Has Annotation?
comp.
In Complex?
sequence
PR:000037483
lysosomal cobalamin transport escort protein LMBD1 isoform 1
LMBRD1/iso:1
organism-sequence
PR:Q6AZ61-1
lysosomal cobalamin transport escort protein LMBD1 isoform 1 (rat)
rLMBRD1/iso:1
organism-sequence
PR:Q8K0B2-1
lysosomal cobalamin transport escort protein LMBD1 isoform 1 (mouse)
mLMBRD1/iso:1
Yes
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:Q8K0B2-1
mLMBRD1/iso:1
acts_upstream_of_or_within
GO:0038016
insulin receptor internalization
MGI_ref:5543853;
PMID:24078630
NOT
GO:0043408
regulation of MAPK cascade
MGI_ref:5543853;
PMID:24078630
GO:0046325
negative regulation of glucose import
MGI_ref:5543853;
PMID:24078630
GO:0046627
negative regulation of insulin receptor signaling pathway
MGI_ref:5543853;
PMID:24078630
GO:0051898
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
MGI_ref:5543853;
PMID:24078630