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Protein Ontology report - cyclin-E
PR:000044430 - http://purl.obolibrary.org/obo/PR_000044430
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000044430   
  PRO namecyclin-E 
  Synonyms
PRO-Short-label: EXACT:fam:CCNE
  Definition"A cyclin-related protein that is a translation product of the human CCNE1 or CCNE2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:DAN] 
  PRO Categoryfamily 
  ParentPR:000029191 cyclin-related protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene2                                                  Organism-Gene 10                                        
         Sequence4                                                  Organism-Sequence 13                                        
         Modification1                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
family



PR:000044430

cyclin-E

fam:CCNE


"A cyclin-related protein that is a translation product of the human CCNE1 or CCNE2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:DAN]


gene



PR:000005125

G1/S-specific cyclin-E1

CCNE1


"A cyclin-E that is a translation product of the human CCNE1 gene or a 1:1 ortholog thereof." [PRO:DNx]


Yes
organism-gene



PR:P24864

G1/S-specific cyclin-E1 (human)

hCCNE1


"A G1/S-specific cyclin-E1 that is encoded in the genome of human." [PRO:DNx]


Yes
organism-sequence



PR:P24864-1

G1/S-specific cyclin-E1 isoform E1L (human)

hCCNE1/iso:E1L


"A G1/S-specific cyclin-E1 isoform 1 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:P24864-2

G1/S-specific cyclin-E1 isoform E1S (human)

hCCNE1/iso:E1S


"A G1/S-specific cyclin-E1 isoform 2 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:P24864-3

G1/S-specific cyclin-E1 isoform 3 (human)

hCCNE1/iso:3


"A G1/S-specific cyclin-E1 isoform 3 that is encoded in the genome of human." [PRO:JAN]


organism-modification



PR:000025637

G1/S-specific cyclin-E1 isoform 3 phosphorylated 1 (human)

hCCNE1/iso:3/Phos:1


"A G1/S-specific cyclin-E1 isoform 3 phosphorylated 1 in human. UniProtKB:P24864-3, Ser-384, MOD:00046." [PMID:16223725, PRO:JAN]

Yes

organism-modification



PR:000066039

G1/S-specific cyclin-E1 cysteinylated 1 (human)

hCCNE1/Cyst:1


"A G1/S-specific cyclin-E1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-156 of the amino acid sequence represented by UniProtKB:P24864-1. Example: UniProtKB:P24864-1, Cys-156, MOD:00765." [IEDB_epitope:1593104, PRO:DNx]


organism-gene



PR:P39949

G1/S-specific cyclin-E1 (rat)

rCCNE1


"A G1/S-specific cyclin-E1 that is encoded in the genome of rat." [OMA:P39949, PRO:DNx]


organism-gene



PR:P47794

G1/S-specific cyclin-E1 (zebrafish)

z-CCNE1


"A G1/S-specific cyclin-E1 that is encoded in the genome of zebrafish." [PRO:DNx]


organism-gene



PR:P49707

G1/S-specific cyclin-E1 (chicken)

chick-CCNE1


"A G1/S-specific cyclin-E1 that is encoded in the genome of chicken." [OMA:P49707, PRO:DNx]


organism-gene



PR:Q61457

G1/S-specific cyclin-E1 (mouse)

mCCNE1


"A G1/S-specific cyclin-E1 that is encoded in the genome of mouse." [OMA:Q61457, PRO:DNx]


organism-sequence



PR:Q61457-1

G1/S-specific cyclin-E1 isoform 1 (mouse)

mCCNE1/iso:1


"A G1/S-specific cyclin-E1 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]


sequence



PR:000025612

G1/S-specific cyclin-E1 isoform 1

CCNE1/iso:1


"A G1/S-specific cyclin-E1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24864-1 or a 1:1 ortholog thereof." [PRO:JAN]


organism-sequence



PR:P24864-1

G1/S-specific cyclin-E1 isoform E1L (human)

hCCNE1/iso:E1L


"A G1/S-specific cyclin-E1 isoform 1 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:Q61457-1

G1/S-specific cyclin-E1 isoform 1 (mouse)

mCCNE1/iso:1


"A G1/S-specific cyclin-E1 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]


sequence



PR:000025614

G1/S-specific cyclin-E1 isoform 2

CCNE1/iso:2


"A G1/S-specific cyclin-E1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24864-2 or a 1:1 ortholog thereof. This isoform lacks a region of around 50 residues within the cyclin box." [PRO:JAN]


organism-sequence



PR:P24864-2

G1/S-specific cyclin-E1 isoform E1S (human)

hCCNE1/iso:E1S


"A G1/S-specific cyclin-E1 isoform 2 that is encoded in the genome of human." [PRO:JAN]


sequence



PR:000025616

G1/S-specific cyclin-E1 isoform 3

CCNE1/iso:3


"A G1/S-specific cyclin-E1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24864-3 or a 1:1 ortholog thereof." [PRO:JAN]


organism-sequence



PR:P24864-3

G1/S-specific cyclin-E1 isoform 3 (human)

hCCNE1/iso:3


"A G1/S-specific cyclin-E1 isoform 3 that is encoded in the genome of human." [PRO:JAN]


organism-modification



PR:000025637

G1/S-specific cyclin-E1 isoform 3 phosphorylated 1 (human)

hCCNE1/iso:3/Phos:1


"A G1/S-specific cyclin-E1 isoform 3 phosphorylated 1 in human. UniProtKB:P24864-3, Ser-384, MOD:00046." [PMID:16223725, PRO:JAN]

Yes

modification



PR:000025618

G1/S-specific cyclin-E1 isoform 3 phosphorylated 1

CCNE1/iso:3/Phos:1


"A G1/S-specific cyclin-E1 isoform 3 that has been phosphorylated by CDK2. Example: UniProtKB:P24864-3, Ser-384, MOD:00046." [PMID:16223725, PRO:DAN, PRO:JAN]


organism-modification



PR:000025637

G1/S-specific cyclin-E1 isoform 3 phosphorylated 1 (human)

hCCNE1/iso:3/Phos:1


"A G1/S-specific cyclin-E1 isoform 3 phosphorylated 1 in human. UniProtKB:P24864-3, Ser-384, MOD:00046." [PMID:16223725, PRO:JAN]

Yes

gene



PR:000005126

G1/S-specific cyclin-E2

CCNE2


"A cyclin-E that is a translation product of the human CCNE2 gene or a 1:1 ortholog thereof." [PRO:DNx]


Yes
organism-gene



PR:O96020

G1/S-specific cyclin-E2 (human)

hCCNE2


"A G1/S-specific cyclin-E2 that is encoded in the genome of human." [PRO:DNx]


Yes
organism-sequence



PR:O96020-1

G1/S-specific cyclin-E2 isoform Long (human)

hCCNE2/iso:Long


"A G1/S-specific cyclin-E2 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:O96020-2

G1/S-specific cyclin-E2 isoform Short (human)

hCCNE2/iso:Short


"A G1/S-specific cyclin-E2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O96020-2." [PRO:DNx, UniProtKB:O96020]


organism-modification



PR:000045625

G1/S-specific cyclin-E2 phosphorylated 1 (human)

hCCNE2/Phos:1


"A G1/S-specific cyclin-E2 (human) that has been phosphorylated on the residue at the position equivalent to Thr-392 of the amino acid sequence represented by UniProtKB:O96020-1. Example: UniProtKB:O96020-1, Thr-392, MOD:00047." [iPTMnet:O96020, PMID:9840943]


organism-modification



PR:000082750

G1/S-specific cyclin-E2 deaminated 1 (human)

hCCNE2/Deam:1


"A G1/S-specific cyclin-E2 (human) that has been deaminated on the residue at the position equivalent to Gln-208 of the amino acid sequence represented by UniProtKB:O96020-1. Example: UniProtKB:O96020-1, Gln-208, MOD:00685." [IEDB_epitope:2140570, PRO:DNx]


organism-gene



PR:Q1PFW3

cyclin-SDS (Arabidopsis thaliana)

At-CCNE2


"A G1/S-specific cyclin-E2 that is encoded in the genome of Arabidopsis thaliana." [OMA:Q1PFW3, PRO:DNx]


organism-sequence



PR:Q1PFW3-1

cyclin-SDS isoform 1 (Arabidopsis thaliana)

At-CCNE2/iso:1


"A cyclin-SDS (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q1PFW3-1." [PRO:DNx, UniProtKB:Q1PFW3]


organism-sequence



PR:Q1PFW3-2

cyclin-SDS isoform 2 (Arabidopsis thaliana)

At-CCNE2/iso:2


"A cyclin-SDS (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q1PFW3-2." [PRO:DNx, UniProtKB:Q1PFW3]


organism-gene



PR:Q9Z238

G1/S-specific cyclin-E2 (mouse)

mCCNE2


"A G1/S-specific cyclin-E2 that is encoded in the genome of mouse." [OMA:Q9Z238, PRO:DNx]


organism-sequence



PR:Q9Z238-1

G1/S-specific cyclin-E2 isoform 1 (mouse)

mCCNE2/iso:1


"A G1/S-specific cyclin-E2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


sequence



PR:000038592

G1/S-specific cyclin-E2 isoform 1

CCNE2/iso:1


"A G1/S-specific cyclin-E2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O96020-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:O96020-1

G1/S-specific cyclin-E2 isoform Long (human)

hCCNE2/iso:Long


"A G1/S-specific cyclin-E2 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q9Z238-1

G1/S-specific cyclin-E2 isoform 1 (mouse)

mCCNE2/iso:1


"A G1/S-specific cyclin-E2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:O01501

G1/S-specific cyclin-E (worm)

cye-1 (worm)


"A cyclin-E that is a translation product of the cye-1 gene in worm." [PRO:DAN, UniProtKB:O01501]


organism-sequence



PR:O01501-1

G1/S-specific cyclin-E isoform a (worm)

fam:CCNE/iso:a (worm)


"A G1/S-specific cyclin-E (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O01501-1." [PRO:DNx, UniProtKB:O01501]


organism-sequence



PR:O01501-2

G1/S-specific cyclin-E isoform b (worm)

fam:CCNE/iso:b (worm)


"A G1/S-specific cyclin-E (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O01501-2." [PRO:DNx, UniProtKB:O01501]


organism-gene



PR:P54733

G1/S-specific cyclin-E (fruit fly)

fly-CycE


"A cyclin-E that is a translation product of the CycE gene in fruit fly." [PRO:DAN, UniProtKB:P54733]


organism-sequence



PR:P54733-1

G1/S-specific cyclin-E isoform II (fruit fly)

fly-CycE/iso:II


"A G1/S-specific cyclin-E (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P54733-1." [PRO:DNx, UniProtKB:P54733]


organism-sequence



PR:P54733-2

G1/S-specific cyclin-E isoform I (fruit fly)

fly-CycE/iso:I


"A G1/S-specific cyclin-E (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P54733-2." [PRO:DNx, UniProtKB:P54733]


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fam:CCNE forms found in complexes   

fam:CCNE Component
Complexes
PR:000005125 CCNE1 PR:000026745 cyclin E1:Cdk2 complex
PR:000027141 cyclin E1:Cdk2 complex phosphorylated form
PR:000005126 CCNE2 PR:000026746 cyclin E2:Cdk2 complex
PR:000027142 cyclin E2:Cdk2 complex phosphorylated form
PR:O96020 hCCNE2 PR:000026769 cyclin E2:Cdk2 complex (human)
PR:000027152 cyclin E2:Cdk2 complex phosphorylated form (human)
PR:P24864 hCCNE1 PR:000026768 cyclin E1:Cdk2 complex (human)
PR:000027151 cyclin E1:Cdk2 complex phosphorylated form (human)
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Molecular Function GO Term

Protein Forms & Complexes

Evidence
GO:0005515 protein bindingPR:000025637 hCCNE1/iso:3/Phos:1 PMID:16223725