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Protein Ontology report - piezo channel protein
PR:000044682 - http://purl.obolibrary.org/obo/PR_000044682
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000044682   
  PRO namepiezo channel protein 
  Synonyms
PRO-Short-label: EXACT:fam:piezo_chan
  Definition"An ion channel protein that is a translation product of the human PIEZO1 or PIEZO2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:XQ] 
  CommentNote: Piezo channels are mechanosensitive ion channels that operate as homotrimers. [PRO:DAN, PMID:29376828]. 
  PRO Categoryfamily 
  ParentPR:000049983 ion channel protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene2                                                  Organism-Gene 6                                        
         Sequence0                                                  Organism-Sequence 10                                        
         Modification0                                                  Organism-Modification 14                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARfam:967
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
family



PR:000044682

piezo channel protein

fam:piezo_chan


"An ion channel protein that is a translation product of the human PIEZO1 or PIEZO2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:XQ]


gene



PR:000030614

piezo-type mechanosensitive ion channel component 1

PIEZO1


"A piezo channel protein that is a translation product of the human PIEZO1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:E2JF22

piezo-type mechanosensitive ion channel component 1 (mouse)

mPIEZO1


"A piezo-type mechanosensitive ion channel component 1 that is encoded in the genome of mouse." [OMA:E2JF22, PRO:DNx]


organism-sequence



PR:000050539

piezo-type mechanosensitive ion channel component 1 isoform m2 (mouse)

mPIEZO1/iso:m2


"A piezo-type mechanosensitive ion channel component 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:E2JF22-1 except that it is missing amino acids 1382-1404. UniProtKB:E2JF22-1, 1-1381, 1405-2547." [PMID:6449305, PRO:HJD]


organism-sequence



PR:E2JF22-1

piezo-type mechanosensitive ion channel component 1 isoform 1 (mouse)

mPIEZO1/iso:1


"A piezo-type mechanosensitive ion channel component 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:E2JF22-1." [PMID:6449305, PRO:HJD]


organism-gene



PR:Q0KL00

piezo-type mechanosensitive ion channel component 1 (rat)

rPIEZO1


"A piezo-type mechanosensitive ion channel component 1 that is encoded in the genome of rat." [OMA:Q0KL00, PRO:DNx]


organism-gene



PR:Q54S52

protein PIEZO homolog (Dictyostelium discoideum)

Dicty-PIEZO1


"A piezo-type mechanosensitive ion channel component 1 that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54S52, PRO:DNx]


organism-gene



PR:Q92508

piezo-type mechanosensitive ion channel component 1 (human)

hPIEZO1


"A piezo-type mechanosensitive ion channel component 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q92508]


organism-modification



PR:000065241

piezo-type mechanosensitive ion channel component 1 deaminated 1 (human)

hPIEZO1/Deam:1


"A piezo-type mechanosensitive ion channel component 1 (human) that has been deaminated on the residue at the position equivalent to Asn-2331 of the amino acid sequence represented by UniProtKB:Q92508. UniProtKB:Q92508, Asn-2331, MOD:00684." [IEDB_epitope:1339707, PRO:DNx]


organism-modification



PR:000067443

piezo-type mechanosensitive ion channel component 1 cysteinylated 1 (human)

hPIEZO1/Cyst:1


"A piezo-type mechanosensitive ion channel component 1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-296 of the amino acid sequence represented by UniProtKB:Q92508. UniProtKB:Q92508, Cys-296, MOD:00765." [IEDB_epitope:1004291, PRO:DNx]


organism-modification



PR:000068165

piezo-type mechanosensitive ion channel component 1 phosphorylated 1 (human)

hPIEZO1/Phos:1


"A piezo-type mechanosensitive ion channel component 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-1870 of the amino acid sequence represented by UniProtKB:Q92508. UniProtKB:Q92508, Ser-1870, MOD:00046." [IEDB_epitope:611174, PRO:DNx]


organism-modification



PR:000068740

piezo-type mechanosensitive ion channel component 1 methylated 1 (human)

hPIEZO1/Me:1


"A piezo-type mechanosensitive ion channel component 1 (human) that has been methylated on the residue at the position equivalent to Cys-262 of the amino acid sequence represented by UniProtKB:Q92508. UniProtKB:Q92508, Cys-262, MOD:00660." [IEDB_epitope:1011632, IEDB_epitope:1011633, PRO:DNx]


organism-modification



PR:000069082

piezo-type mechanosensitive ion channel component 1 deaminated 2 (human)

hPIEZO1/Deam:2


"A piezo-type mechanosensitive ion channel component 1 (human) that has been deaminated on the residue at the position equivalent to Gln-2228 of the amino acid sequence represented by UniProtKB:Q92508. UniProtKB:Q92508, Gln-2228, MOD:00685." [IEDB_epitope:1812840, PRO:DNx]


organism-modification



PR:000070670

piezo-type mechanosensitive ion channel component 1 methylated 2 (human)

hPIEZO1/Me:2


"A piezo-type mechanosensitive ion channel component 1 (human) that has been methylated on the residue at the position equivalent to Cys-1064 of the amino acid sequence represented by UniProtKB:Q92508. UniProtKB:Q92508, Cys-1064, MOD:00660." [IEDB_epitope:1034015, PRO:DNx]


organism-modification



PR:000072532

piezo-type mechanosensitive ion channel component 1 methylated 3 (human)

hPIEZO1/Me:3


"A piezo-type mechanosensitive ion channel component 1 (human) that has been methylated on the residue at the position equivalent to Cys-1691 of the amino acid sequence represented by UniProtKB:Q92508. UniProtKB:Q92508, Cys-1691, MOD:00660." [IEDB_epitope:999622, PRO:DNx]


organism-modification



PR:000079182

piezo-type mechanosensitive ion channel component 1 phosphorylated 2 (human)

hPIEZO1/Phos:2


"A piezo-type mechanosensitive ion channel component 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-1646 of the amino acid sequence represented by UniProtKB:Q92508. UniProtKB:Q92508, Ser-1646, MOD:00046." [IEDB_epitope:2149277, PRO:DNx]


organism-modification



PR:000081846

piezo-type mechanosensitive ion channel component 1 deaminated 3 (human)

hPIEZO1/Deam:3


"A piezo-type mechanosensitive ion channel component 1 (human) that has been deaminated on the residue at the position equivalent to Asn-658 of the amino acid sequence represented by UniProtKB:Q92508. UniProtKB:Q92508, Asn-658, MOD:00684." [IEDB_epitope:1353421, IEDB_epitope:1377241, PRO:DNx]


organism-modification



PR:000083616

piezo-type mechanosensitive ion channel component 1 methylated 4 (human)

hPIEZO1/Me:4


"A piezo-type mechanosensitive ion channel component 1 (human) that has been methylated on the residue at the position equivalent to Cys-296 of the amino acid sequence represented by UniProtKB:Q92508. UniProtKB:Q92508, Cys-296, MOD:00660." [IEDB_epitope:1004292, PRO:DNx]


gene



PR:000032708

piezo-type mechanosensitive ion channel component 2

PIEZO2


"A piezo channel protein that is a translation product of the human PIEZO2 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q8CD54

piezo-type mechanosensitive ion channel component 2 (mouse)

mPIEZO2


"A piezo-type mechanosensitive ion channel component 2 that is encoded in the genome of mouse." [OMA:Q8CD54, PRO:DNx]


organism-sequence



PR:000050540

piezo-type mechanosensitive ion channel component 2 isoform m4 (mouse)

mPIEZO2/iso:m4


"A piezo-type mechanosensitive ion channel component 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CD54-1 except that it is missing amino acids 1539-1561. UniProtKB:Q8CD54-1, 1-1538, 1562-2822." [PMID:6449305, PRO:HJD]


organism-sequence



PR:Q8CD54-1

piezo-type mechanosensitive ion channel component 2 isoform m1 (mouse)

mPIEZO2/iso:m1


"A piezo-type mechanosensitive ion channel component 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CD54-1." [PRO:DNx, UniProtKB:Q8CD54]


organism-sequence



PR:Q8CD54-2

piezo-type mechanosensitive ion channel component 2 isoform m2 (mouse)

mPIEZO2/iso:m2


"A piezo-type mechanosensitive ion channel component 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CD54-2." [PRO:DNx, UniProtKB:Q8CD54]


organism-sequence



PR:Q8CD54-3

piezo-type mechanosensitive ion channel component 2 isoform m3 (mouse)

mPIEZO2/iso:m3


"A piezo-type mechanosensitive ion channel component 2 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8CD54-3." [PRO:DNx, UniProtKB:Q8CD54]


organism-gene



PR:Q9H5I5

piezo-type mechanosensitive ion channel component 2 (human)

hPIEZO2


"A piezo-type mechanosensitive ion channel component 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9H5I5]


organism-sequence



PR:Q9H5I5-1

piezo-type mechanosensitive ion channel component 2 isoform h1 (human)

hPIEZO2/iso:h1


"A piezo-type mechanosensitive ion channel component 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H5I5-1." [PRO:DNx, UniProtKB:Q9H5I5]


organism-sequence



PR:Q9H5I5-2

piezo-type mechanosensitive ion channel component 2 isoform h2 (human)

hPIEZO2/iso:h2


"A piezo-type mechanosensitive ion channel component 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H5I5-2." [PRO:DNx, UniProtKB:Q9H5I5]


organism-sequence



PR:Q9H5I5-3

piezo-type mechanosensitive ion channel component 2 isoform h3 (human)

hPIEZO2/iso:h3


"A piezo-type mechanosensitive ion channel component 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H5I5-3." [PRO:DNx, UniProtKB:Q9H5I5]


organism-sequence



PR:Q9H5I5-4

piezo-type mechanosensitive ion channel component 2 isoform h4 (human)

hPIEZO2/iso:h4


"A piezo-type mechanosensitive ion channel component 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9H5I5-4." [PRO:DNx, UniProtKB:Q9H5I5]


organism-modification



PR:000065705

piezo-type mechanosensitive ion channel component 2 methylated 1 (human)

hPIEZO2/Me:1


"A piezo-type mechanosensitive ion channel component 2 (human) that has been methylated on the residue at the position equivalent to Cys-503 of the amino acid sequence represented by UniProtKB:Q9H5I5-1. Example: UniProtKB:Q9H5I5-1, Cys-503, MOD:00660." [IEDB_epitope:1052915, PRO:DNx]


organism-modification



PR:000078696

piezo-type mechanosensitive ion channel component 2 deaminated 1 (human)

hPIEZO2/Deam:1


"A piezo-type mechanosensitive ion channel component 2 (human) that has been deaminated on the residue at the position equivalent to Asn-2654 of the amino acid sequence represented by UniProtKB:Q9H5I5-1. Example: UniProtKB:Q9H5I5-1, Asn-2654, MOD:00684." [IEDB_epitope:1977465, PRO:DNx]


organism-modification



PR:000080414

piezo-type mechanosensitive ion channel component 2 cysteinylated 1 (human)

hPIEZO2/Cyst:1


"A piezo-type mechanosensitive ion channel component 2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-7 of the amino acid sequence represented by UniProtKB:Q9H5I5-1. Example: UniProtKB:Q9H5I5-1, Cys-7, MOD:00765." [IEDB_epitope:1010447, PRO:DNx]


organism-modification



PR:000083888

piezo-type mechanosensitive ion channel component 2 methylated 2 (human)

hPIEZO2/Me:2


"A piezo-type mechanosensitive ion channel component 2 (human) that has been methylated on the residue at the position equivalent to Cys-7 of the amino acid sequence represented by UniProtKB:Q9H5I5-1. Example: UniProtKB:Q9H5I5-1, Cys-7, MOD:00660." [IEDB_epitope:1010448, IEDB_epitope:1059771, PRO:DNx]