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Protein Ontology report - neuregulin-1 intracellular domain (mouse)
PR:000044843 - http://purl.obolibrary.org/obo/PR_000044843
 
    Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:000044843   
  PRO nameneuregulin-1 intracellular domain (mouse) 
  Synonyms
PRO-Short-label: EXACT:mNRG1/Clv:intracellular
PRO-proteoform-std: NARROW:UniProtKB:Q6DR99, 326-700
Other: RELATED:NRG1 ICD (mouse)
  Definition"A pro-neuregulin-1, membrane-bound isoform (mouse) that corresponds to the intracellular domain after proteolytic cleavage. Example: UniProtKB:Q6DR99, 326-700." [PMID:20610754, PMID:24083437, PRO:KRC] 
  CommentEvidence=(ECO:0000205, based on PMID:24083437). 
  PRO Categoryorganism-modification 
  ParentPR:000029651 pro-neuregulin-1, membrane-bound isoform proteolytic cleavage product
PR:Q6DR98 pro-neuregulin-1, membrane-bound isoform (mouse)
  TaxonNCBITaxon:10090 Mus musculus
  Term Hierarchy
  Visualization
DAG: OLS:
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0022008 neurogenesisPR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
PR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646
NOT GO:0045773 positive regulation of axon extensionPR:000044843 mNRG1/Clv:intracellular MGI_ref:4461331; PMID:20610754
GO:0045944 positive regulation of transcription by RNA polymerase IIPR:000044843 mNRG1/Clv:intracellular MGI_ref:4461331; PMID:20610754

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0005515 protein bindingPR:000044843 mNRG1/Clv:intracellular MGI_ref:4438553; PMID:19781646

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005634 nucleusPR:000044843 mNRG1/Clv:intracellular MGI_ref:4461331; PMID:20610754