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Protein Ontology report - TTK activation loop phosphorylated form (human)
PR:000049844 -
http://purl.obolibrary.org/obo/PR_000049844
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:000049844
PRO name
TTK activation loop phosphorylated form (human)
Synonyms
PRO-Short-label
:
EXACT:
hTTK/(Act-loop)Phos+
PRO-proteoform-std
:
EXACT:
UniProtKB:P33981
, (Thr-675,
MOD:00047
or Thr-676,
MOD:00047
or Ser-677,
MOD:00046
)
NARROW:
UniProtKB:P33981
, Ser-677,
MOD:00046
|
UniProtKB:P33981
, Thr-675,
MOD:00047
|
UniProtKB:P33981
, Thr-676,
MOD:00047
|
UniProtKB:P33981-1
, (Thr-675,
MOD:00047
or Thr-676,
MOD:00047
or Ser-677,
MOD:00046
) |
UniProtKB:P33981-1
, Ser-677,
MOD:00046
|
UniProtKB:P33981-1
, Thr-675,
MOD:00047
|
UniProtKB:P33981-1
, Thr-676,
MOD:00047
Definition
"A dual specificity protein kinase TTK (human) that has been phosphorylated on one of three sites within the activation loop, at positions equivalent to Thr-675 or Thr-676 or Ser-677 of the amino acid sequence represented by
UniProtKB:P33981-1
. Example:
UniProtKB:P33981-1
, (Thr-675,
MOD:00047
or Thr-676,
MOD:00047
or Ser-677,
MOD:00046
)." [
PMID:17728254
,
PMID:18923149
,
PMID:19120698
, PRO:KER]
Comment
Evidence=(ECO:0000006, based on
PMID:17728254
). Evidence=(ECO:0000006, based on
PMID:19120698
). Evidence=(ECO:0000006, based on
PMID:18923149
). Kinase=("TTK";
PR:P33981
; Thr-675). Kinase=("TTK";
PR:P33981
; Thr-676). Kinase=("TTK";
PR:P33981
; Ser-677).
PRO Category
organism-modification
Parent
PR:000037070
phosphoprotein
PR:P33981
dual specificity protein kinase TTK (human)
Taxon
NCBITaxon:9606
Homo sapiens
Term Hierarchy
Visualization
DAG:
OLS:
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000049844
hTTK/(Act-loop)Phos+
Example: UniProtKB:P33981-1, (Thr-675, MOD:00047 or Thr-676, MOD:00047 or Ser-677, MOD:00046)
acts_upstream_of_or_within
GO:0046777
protein autophosphorylation
PMID:18680479
;
PMID:19120698
enables
GO:0004672
protein kinase activity
PMID:18680479
;
PMID:19120698