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Protein Ontology report - TTK activation loop and P+1 loop phosphorylated form (human)
PR:000049845 -
http://purl.obolibrary.org/obo/PR_000049845
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:000049845
PRO name
TTK activation loop and P+1 loop phosphorylated form (human)
Synonyms
PRO-Short-label
:
EXACT:
hTTK/(Act-loop_P+1-loop)Phos+
PRO-proteoform-std
:
EXACT:
UniProtKB:P33981
, (Thr-675,
MOD:00047
or Thr-676,
MOD:00047
or Ser-677,
MOD:00046
)|Thr-686,
MOD:00047
NARROW:
UniProtKB:P33981
, Ser-677,
MOD:00046
|Thr-686,
MOD:00047
|
UniProtKB:P33981
, Thr-675,
MOD:00047
|Thr-686,
MOD:00047
|
UniProtKB:P33981
, Thr-676,
MOD:00047
|Thr-686,
MOD:00047
|
UniProtKB:P33981-1
, (Thr-675,
MOD:00047
or Thr-676,
MOD:00047
or Ser-677,
MOD:00046
)|Thr-686,
MOD:00047
|
UniProtKB:P33981-1
, Ser-677,
MOD:00046
|Thr-686,
MOD:00047
|
UniProtKB:P33981-1
, Thr-675,
MOD:00047
|Thr-686,
MOD:00047
|
UniProtKB:P33981-1
, Thr-676,
MOD:00047
|Thr-686,
MOD:00047
Definition
"A dual specificity protein kinase TTK (human) that has been phosphorylated on one of three sites within the activation loop and on a Thr residue in the P+1 loop. Example:
UniProtKB:P33981-1
, (Thr-675,
MOD:00047
or Thr-676,
MOD:00047
or Ser-677,
MOD:00046
)|Thr-686,
MOD:00047
." [
PMID:19120698
, PRO:KER]
Comment
Evidence=(ECO:0000006, based on
PMID:19120698
). Kinase=("TTK";
PR:P33981
; Thr-675). Kinase=("TTK";
PR:P33981
; Thr-676). Kinase=("TTK";
PR:P33981
; Ser-677). Kinase=("TTK";
PR:P33981
; Thr-686).
PRO Category
organism-modification
Parent
PR:000037070
phosphoprotein
PR:P33981
dual specificity protein kinase TTK (human)
Taxon
NCBITaxon:9606
Homo sapiens
Term Hierarchy
Visualization
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Functional Annotation (PRO-centric view)
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PRO Term
GO Annotation
Evidence
PR:000049845
hTTK/(Act-loop_P+1-loop)Phos+
Example: UniProtKB:P33981-1, (Thr-675, MOD:00047 or Thr-676, MOD:00047 or Ser-677, MOD:00046)|Thr-686, MOD:00047
enables
GO:0004672
protein kinase activity
PMID:19120698