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Protein Ontology report - glycogen synthase kinase 3
PR:000050019 - http://purl.obolibrary.org/obo/PR_000050019
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000050019   
  PRO nameglycogen synthase kinase 3 
  Synonyms
PRO-Short-label: EXACT:fam:GSK3
  Definition"A GSK3-like glycogen synthase kinase that is a translation product of the human GSK3A or GSK3B genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:DAN] 
  CommentRequested by=CRAFT. 
  PRO Categoryfamily 
  ParentPR:000035899 GSK3-like glycogen synthase kinase
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene2                                                  Organism-Gene 12                                        
         Sequence1                                                  Organism-Sequence 8                                        
         Modification0                                                  Organism-Modification 14                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
family



PR:000050019

glycogen synthase kinase 3

fam:GSK3


"A GSK3-like glycogen synthase kinase that is a translation product of the human GSK3A or GSK3B genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:DAN]


gene



PR:000008287

glycogen synthase kinase-3 alpha

GSK3A


"A glycogen synthase kinase 3 that is a translation product of the human GSK3A gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P18265

glycogen synthase kinase-3 alpha (rat)

rGSK3A


"A glycogen synthase kinase-3 alpha that is encoded in the genome of rat." [OMA:P18265, PRO:DNx]


organism-modification



PR:000046146

glycogen synthase kinase-3 alpha phosphorylated 1 (rat)

rGsk3a/Phos:1


"A glycogen synthase kinase-3 alpha (rat) that has been phosphorylated at Ser-21. UniProtKB:P18265, Ser-21, MOD:00046." [iPTMnet:P18265, PMID:11978789]


organism-gene



PR:P49840

glycogen synthase kinase-3 alpha (human)

hGSK3A


"A glycogen synthase kinase-3 alpha that is encoded in the genome of human." [PRO:DNx, UniProtKB:P49840]


organism-modification



PR:000045808

glycogen synthase kinase-3 alpha phosphorylated 1 (human)

hGSK3A/Phos:1


"A glycogen synthase kinase-3 alpha (human) that has been phosphorylated at Ser-21. UniProtKB:P49840, Ser-21, MOD:00046." [iPTMnet:P49840, PMID:11035810]


organism-modification



PR:000047634

glycogen synthase kinase-3 alpha, initiator methionine removed form (human)

hGSK3A/InitMet-


"A glycogen synthase kinase-3 alpha (human) that has had the initiator methionine removed. UniProtKB:P49840, 2-483." [PRO:DNx, Reactome:R-HSA-198326]


organism-modification



PR:000068970

glycogen synthase kinase-3 alpha methylated 1 (human)

hGSK3A/Me:1


"A glycogen synthase kinase-3 alpha (human) that has been methylated on the residue at the position equivalent to Cys-398 of the amino acid sequence represented by UniProtKB:P49840. UniProtKB:P49840, Cys-398, MOD:00660." [IEDB_epitope:1003847, PRO:DNx]


organism-modification



PR:000075258

glycogen synthase kinase-3 alpha deaminated 1 (human)

hGSK3A/Deam:1


"A glycogen synthase kinase-3 alpha (human) that has been deaminated on the residue at the position equivalent to Gln-227 of the amino acid sequence represented by UniProtKB:P49840. UniProtKB:P49840, Gln-227, MOD:00685." [IEDB_epitope:1584206, PRO:DNx]


organism-modification



PR:000081460

glycogen synthase kinase-3 alpha cysteinylated 1 (human)

hGSK3A/Cyst:1


"A glycogen synthase kinase-3 alpha (human) that has been cysteinylated on the residue at the position equivalent to Cys-398 of the amino acid sequence represented by UniProtKB:P49840. UniProtKB:P49840, Cys-398, MOD:00765." [IEDB_epitope:1003846, PRO:DNx]


organism-gene



PR:Q2NL51

glycogen synthase kinase-3 alpha (mouse)

mGSK3A


"A glycogen synthase kinase-3 alpha that is encoded in the genome of mouse." [OMA:Q2NL51, PRO:DNx]


organism-modification



PR:000046200

glycogen synthase kinase-3 alpha phosphorylated 1 (mouse)

mGSK3A/Phos:1


"A glycogen synthase kinase-3 alpha (mouse) that has been phosphorylated at Ser-21. UniProtKB:Q2NL51, Ser-21, MOD:00046." [iPTMnet:Q2NL51, PMID:15791206]


gene



PR:000008288

glycogen synthase kinase-3 beta

GSK3B


"A glycogen synthase kinase 3 that is a translation product of the human GSK3B gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P18266

glycogen synthase kinase-3 beta (rat)

rGSK3B


"A glycogen synthase kinase-3 beta that is encoded in the genome of rat." [OMA:P18266, PRO:DNx]


organism-sequence



PR:P18266-1

glycogen synthase kinase-3 beta isoform 1 (rat)

rGSK3B/iso:1


"A glycogen synthase kinase-3 beta isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-modification



PR:000045698

glycogen synthase kinase-3 beta phosphorylated 1 (rat)

rGSK3B/Phos:1


"A glycogen synthase kinase-3 beta (rat) that has been phosphorylated at Ser-9. UniProtKB:P18266, Ser-9, MOD:00046." [iPTMnet:P18266, PMID:11094086, PMID:12421827]


organism-gene



PR:P18431

protein kinase shaggy (fruit fly)

fly-GSK3B


"A glycogen synthase kinase-3 beta that is encoded in the genome of fruit fly." [PRO:DNx]


organism-sequence



PR:P18431-1

protein kinase shaggy isoform SGG46 (fruit fly)

fly-GSK3B/iso:SGG46


"A protein kinase shaggy (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18431-1." [PRO:DNx, UniProtKB:P18431]


organism-sequence



PR:P18431-2

protein kinase shaggy isoform Zygotic (fruit fly)

fly-GSK3B/iso:Zygotic


"A protein kinase shaggy (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18431-2." [PRO:DNx, UniProtKB:P18431]


organism-sequence



PR:P18431-3

protein kinase shaggy isoform SGG39 (fruit fly)

fly-GSK3B/iso:SGG39


"A protein kinase shaggy (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18431-3." [PRO:DNx, UniProtKB:P18431]


organism-sequence



PR:P18431-4

protein kinase shaggy isoform G (fruit fly)

fly-GSK3B/iso:G


"A protein kinase shaggy (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18431-4." [PRO:DNx, UniProtKB:P18431]


organism-gene



PR:P38615

serine/threonine-protein kinase RIM11/MSD1 (yeast)

yGSK3B


"A glycogen synthase kinase-3 beta that is encoded in the genome of yeast." [OMA:P38615, PRO:DNx]


organism-modification



PR:000046173

serine/threonine-protein kinase RIM11/MSD1 phosphorylated 1 (yeast)

yGSK3B/Phos:1


"A serine/threonine-protein kinase RIM11/MSD1 (yeast) that has been phosphorylated at Tyr-199. UniProtKB:P38615, Tyr-199, MOD:00048." [iPTMnet:P38615, PMID:10679022]


organism-gene



PR:P49841

glycogen synthase kinase-3 beta (human)

hGSK3B


"A glycogen synthase kinase-3 beta that is encoded in the genome of human." [PRO:DNx, UniProtKB:P49841]


organism-sequence



PR:P49841-1

glycogen synthase kinase-3 beta isoform 1 (human)

hGSK3B/iso:1


"A glycogen synthase kinase-3 beta isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P49841-2

glycogen synthase kinase-3 beta isoform h2 (human)

hGSK3B/iso:h2


"A glycogen synthase kinase-3 beta (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49841-2." [PRO:DNx, UniProtKB:P49841]


organism-modification



PR:000045809

glycogen synthase kinase-3 beta phosphorylated 1 (human)

hGSK3B/Phos:1


"A glycogen synthase kinase-3 beta (human) that has been phosphorylated on the residue at the position equivalent to Tyr-216 of the amino acid sequence represented by UniProtKB:P49841-1. Example: UniProtKB:P49841-1, Tyr-216, MOD:00048." [iPTMnet:P49841, PMID:15020233, PMID:17188038]


organism-modification



PR:000047635

glycogen synthase kinase-3 beta phosphorylated 2 (human)

hGSK3B/Phos:2


"A glycogen synthase kinase-3 beta (human) that has been phosphorylated on the residue at the position equivalent to Ser-9 of the amino acid sequence represented by UniProtKB:P49841. UniProtKB:P49841, Ser-9, MOD:00046." [PRO:DNx, Reactome:R-HSA-3149577]


organism-modification



PR:000067381

glycogen synthase kinase-3 beta cysteinylated 1 (human)

hGSK3B/Cyst:1


"A glycogen synthase kinase-3 beta (human) that has been cysteinylated on the residue at the position equivalent to Cys-317 of the amino acid sequence represented by UniProtKB:P49841-1. Example: UniProtKB:P49841-1, Cys-317, MOD:00765." [IEDB_epitope:1000222, PRO:DNx]


organism-gene



PR:Q9WV60

glycogen synthase kinase-3 beta (mouse)

mGSK3B


"A glycogen synthase kinase-3 beta that is encoded in the genome of mouse." [OMA:Q9WV60, PRO:DNx]


organism-sequence



PR:Q9WV60-1

glycogen synthase kinase-3 beta isoform 1 (mouse)

mGSK3B/iso:1


"A glycogen synthase kinase-3 beta isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-modification



PR:000046095

glycogen synthase kinase-3 beta phosphorylated 1 (mouse)

mGSK3B/Phos:1


"A glycogen synthase kinase-3 beta (mouse) that has been phosphorylated at Ser-9. UniProtKB:Q9WV60, Ser-9, MOD:00046." [iPTMnet:Q9WV60, PMID:16522636, PMID:26582204, PRO:HJD]


organism-modification



PR:000049789

glycogen synthase kinase-3 beta unphosphorylated 1 (mouse)

mGSK3B/UnPhos:1


"A glycogen synthase kinase-3 beta (mouse) that lacks phosphorylation at the position equivalent to Ser-9 of the amino acid sequence represented by UniProtKB:Q9WV60. UniProtKB:Q9WV60, Ser-9, PR:000026291." [PMID:26582204, PRO:HJD]


sequence



PR:000039611

glycogen synthase kinase-3 beta isoform 1

GSK3B/iso:1


"A glycogen synthase kinase-3 beta that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49841-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P18266-1

glycogen synthase kinase-3 beta isoform 1 (rat)

rGSK3B/iso:1


"A glycogen synthase kinase-3 beta isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P49841-1

glycogen synthase kinase-3 beta isoform 1 (human)

hGSK3B/iso:1


"A glycogen synthase kinase-3 beta isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q9WV60-1

glycogen synthase kinase-3 beta isoform 1 (mouse)

mGSK3B/iso:1


"A glycogen synthase kinase-3 beta isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:P51136

glycogen synthase kinase-3 (Dictyostelium discoideum)

Dicty-gskA


"A glycogen synthase kinase 3 that is a translation product of the gskA gene in Dictyostelium discoideum." [PRO:DAN]


organism-gene



PR:P83101

putative glycogen synthase kinase-3 homolog (fruit fly)

fly-gskt


"A glycogen synthase kinase 3 that is a translation product of the gskt gene in fruit fly." [PRO:DAN]


organism-gene



PR:Q10452

protein kinase gsk3 (Schizosaccharomyces pombe 972h-)

Spom972h-gsk3


"A glycogen synthase kinase 3 that is a translation product of the gsk3 gene in Schizosaccharomyces pombe 972h-." [PRO:DAN]


organism-gene



PR:Q9U2Q9

glycogen synthase kinase-3 (worm)

gsk-3 (worm)


"A glycogen synthase kinase 3 that is a translation product of the gsk-3 gene in worm." [PRO:DAN]