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Protein Ontology report - kinetochore protein NDC80 (human)
PR:O14777 - http://purl.obolibrary.org/obo/PR_O14777
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:O14777   
  PRO namekinetochore protein NDC80 (human) 
  Synonyms
PRO-Short-label: EXACT:hNDC80
Gene-based: RELATED:HEC | HEC1 | KNTC2 | NDC80
Other: EXACT:highly expressed in cancer protein (human) | HsHec1 | kinetochore protein Hec1 (human) | kinetochore-associated protein 2 (human) | retinoblastoma-associated protein HEC (human)
  Definition"A kinetochore protein NDC80 that is encoded in the genome of human." [PMID:17785528, PMID:20624902, PRO:KER] 
  PRO Categoryorganism-gene 
  ParentPR:000011050 kinetochore protein NDC80
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:16909 NDC80 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 10                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:O14777
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
organism-gene



PR:O14777

kinetochore protein NDC80 (human)

hNDC80


"A kinetochore protein NDC80 that is encoded in the genome of human." [PMID:17785528, PMID:20624902, PRO:KER]

Yes

organism-sequence



PR:O14777-1

kinetochore protein NDC80 homolog isoform 1 (human)

hNDC80/iso:1


"A kinetochore protein NDC80 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000045569

kinetochore protein NDC80 phosphorylated 1 (human)

hNDC80/Phos:1


"A kinetochore protein NDC80 (human) that has been phosphorylated at Ser-165. UniProtKB:O14777, Ser-165, MOD:00046." [iPTMnet:O14777, PMID:18297113, PMID:21832156]


organism-modification



PR:000066076

kinetochore protein NDC80 deaminated 1 (human)

hNDC80/Deam:1


"A kinetochore protein NDC80 (human) that has been deaminated on the residue at the position equivalent to Asn-332 of the amino acid sequence represented by UniProtKB:O14777. UniProtKB:O14777, Asn-332, MOD:00684." [IEDB_epitope:2139875, PRO:DNx]


organism-modification



PR:000068345

kinetochore protein NDC80 deaminated 2 (human)

hNDC80/Deam:2


"A kinetochore protein NDC80 (human) that has been deaminated on the residue at the position equivalent to Asn-276 of the amino acid sequence represented by UniProtKB:O14777. UniProtKB:O14777, Asn-276, MOD:00684." [IEDB_epitope:1348961, PRO:DNx]


organism-modification



PR:000069025

kinetochore protein NDC80 cysteinylated 1 (human)

hNDC80/Cyst:1


"A kinetochore protein NDC80 (human) that has been cysteinylated on the residue at the position equivalent to Cys-191 of the amino acid sequence represented by UniProtKB:O14777. UniProtKB:O14777, Cys-191, MOD:00765." [IEDB_epitope:1563373, PRO:DNx]


organism-modification



PR:000072892

kinetochore protein NDC80 methylated 1 (human)

hNDC80/Me:1


"A kinetochore protein NDC80 (human) that has been methylated on the residue at the position equivalent to Cys-95 of the amino acid sequence represented by UniProtKB:O14777. UniProtKB:O14777, Cys-95, MOD:00660." [IEDB_epitope:1012009, PRO:DNx]


organism-modification



PR:000076086

kinetochore protein NDC80 phosphorylated 2 (human)

hNDC80/Phos:2


"A kinetochore protein NDC80 (human) that has been phosphorylated on the residue at the position equivalent to Thr-635 of the amino acid sequence represented by UniProtKB:O14777. UniProtKB:O14777, Thr-635, MOD:00047." [IEDB_epitope:2146963, PRO:DNx]


organism-modification



PR:000078733

kinetochore protein NDC80 methylated 2 (human)

hNDC80/Me:2


"A kinetochore protein NDC80 (human) that has been methylated on the residue at the position equivalent to Cys-342 of the amino acid sequence represented by UniProtKB:O14777. UniProtKB:O14777, Cys-342, MOD:00660." [IEDB_epitope:1046533, PRO:DNx]


organism-modification



PR:000079460

kinetochore protein NDC80 cysteinylated 2 (human)

hNDC80/Cyst:2


"A kinetochore protein NDC80 (human) that has been cysteinylated on the residue at the position equivalent to Cys-449 of the amino acid sequence represented by UniProtKB:O14777. UniProtKB:O14777, Cys-449, MOD:00765." [IEDB_epitope:1582540, PRO:DNx]


organism-modification



PR:000083884

kinetochore protein NDC80 deaminated 3 (human)

hNDC80/Deam:3


"A kinetochore protein NDC80 (human) that has been deaminated on the residue at the position equivalent to Gln-278 of the amino acid sequence represented by UniProtKB:O14777. UniProtKB:O14777, Gln-278, MOD:00685." [IEDB_epitope:1348962, PRO:DNx]


organism-modification



PR:000084178

kinetochore protein NDC80 phosphorylated 3 (human)

hNDC80/Phos:3


"A kinetochore protein NDC80 (human) that has been phosphorylated on the residue at the position equivalent to Thr-572 of the amino acid sequence represented by UniProtKB:O14777. UniProtKB:O14777, Thr-572, MOD:00047." [IEDB_epitope:2149303, PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:O14777 hNDC80 acts_upstream_of_or_withinGO:0034501 protein localization to kinetochore PMID:17785528
enablesGO:0005515 protein binding with PR:Q8NG31 AF15q14 (human) BioGRID:BG-252640; IntAct:EBI-999882
GO:0005515 protein binding with PR:Q9BZD4 CDCA1 BioGRID:BG-252640; IntAct:EBI-999882
located_inGO:0000776 kinetochore PMID:20624902