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Protein Ontology report - neuropilin-1 (human)
PR:O14786 - http://purl.obolibrary.org/obo/PR_O14786
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:O14786   
  PRO nameneuropilin-1 (human) 
  Synonyms
PRO-Short-label: EXACT:hNRP1
Gene-based: RELATED:NRP | NRP1 | VEGF165R
Other: EXACT:CD304 (human) | vascular endothelial cell growth factor 165 receptor (human)
  Definition"A neuropilin-1 that is encoded in the genome of human." [PRO:WCB, UniProtKB:O14786] 
  PRO Categoryorganism-gene 
  ParentPR:000001900 neuropilin-1
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:8004 NRP1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 8                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:O14786
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
organism-gene


PR:O14786 neuropilin-1 (human)
hNRP1

organism-sequence


PR:O14786-1 neuropilin-1 isoform 1 (human)
hNRP1/iso:1

organism-modification


PR:000036635 neuropilin-1 isoform 1, signal peptide removed form (human)
hNRP1/iso:1/SigPep-
Yes
organism-modification


PR:000036631 neuropilin-1 isoform 1, signal peptide removed O-glycosylated 1 (human)
hNRP1/iso:1/ClvOGlyco:1
Yes
organism-modification


PR:000036632 neuropilin-1 isoform 1, signal peptide removed O-glycosylated 2 (human)
hNRP1/iso:1/ClvOGlyco:2
Yes
organism-sequence


PR:O14786-2 neuropilin-1 isoform 2 (human)
hNRP1/iso:2

organism-sequence


PR:O14786-3 neuropilin-1 isoform h3 (human)
hNRP1/iso:h3

organism-modification


PR:000050705 neuropilin-1 N-glycosylated 1 (human)
hNRP1/NGlyco:1

organism-modification


PR:000050706 neuropilin-1 O-glycosylated 1 (human)
hNRP1/OGlyco:1

organism-modification


PR:000050707 neuropilin-1 O-glycosylated 2 (human)
hNRP1/OGlyco:2

organism-modification


PR:000050708 neuropilin-1 O-glycosylated 3 (human)
hNRP1/OGlyco:3

organism-modification


PR:000050709 neuropilin-1 O-glycosylated 4 (human)
hNRP1/OGlyco:4

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036631 hNRP1/iso:1/ClvOGlyco:1
UniProtKB:O14786-1, 22-923, Ser-612, MOD:00215		 acts_upstream_of_or_withinGO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway PMID:16763549
enablesincreased GO:0005515 protein binding with PR:P15692-4 PMID:16763549
GO:0043184 vascular endothelial growth factor receptor 2 binding PMID:16763549
PR:000036632 hNRP1/iso:1/ClvOGlyco:2
UniProtKB:O14786-1, 22-923, Ser-612, MOD:00213		 acts_upstream_of_or_withinGO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway PMID:16763549
enablesincreased GO:0005515 protein binding with PR:P15692-4 PMID:16763549
decreased GO:0043184 vascular endothelial growth factor receptor 2 binding relative to PR:000036635 hNRP1/iso:1/SigPep- PMID:16763549
PR:000036635 hNRP1/iso:1/SigPep-
UniProtKB:O14786-1, 22-923		 enablesGO:0005515 protein binding with PR:P15692-4 PMID:11986311
GO:0005515 protein binding with PR:P15692-4 PMID:11986311
GO:0005515 protein binding with PR:P49763-3 PMID:11986311
GO:0008201 heparin binding PMID:11986311
GO:0043184 vascular endothelial growth factor receptor 2 binding PMID:16763549