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Protein Ontology report - potassium voltage-gated channel subfamily KQT member 2 (human)
PR:O43526 - http://purl.obolibrary.org/obo/PR_O43526
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:O43526   
  PRO namepotassium voltage-gated channel subfamily KQT member 2 (human) 
  Synonyms
PRO-Short-label: EXACT:hKCNQ2
Gene-based: RELATED:KCNQ2
Other: EXACT:KQT-like 2 (human) | neuroblastoma-specific potassium channel subunit alpha KvLQT2 (human) | voltage-gated potassium channel subunit Kv7.2 (human)
  Definition"A voltage-gated potassium channel subunit KCNQ2 that is encoded in the genome of human." [] 
  PRO Categoryorganism-gene 
  ParentPR:000000729 voltage-gated potassium channel subunit KCNQ2
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:6296 KCNQ2 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 16                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:O43526
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
organism-gene


PR:O43526 potassium voltage-gated channel subfamily KQT member 2 (human)
hKCNQ2

organism-sequence


PR:000000907 voltage-gated potassium channel subunit KCNQ2 sequence variant S247W (human)
hKCNQ2/var:S247W
Yes
organism-sequence


PR:000000908 voltage-gated potassium channel subunit KCNQ2 sequence variant H228Q (human)
hKCNQ2/var:H228Q
Yes
organism-sequence


PR:000000909 voltage-gated potassium channel subunit KCNQ2 sequence variant R207W (human)
hKCNQ2/var:R207W
Yes
organism-sequence


PR:000000910 voltage-gated potassium channel subunit KCNQ2 sequence variant L243F (human)
hKCNQ2/var:L243F
Yes
organism-sequence


PR:000000911 voltage-gated potassium channel subunit KCNQ2 sequence variant 4 (human)
hKCNQ2/var:4
Yes
organism-sequence


PR:000000912 voltage-gated potassium channel subunit KCNQ2 sequence variant Y284C (human)
hKCNQ2/var:Y284C
Yes
organism-sequence


PR:000000913 voltage-gated potassium channel subunit KCNQ2 sequence variant A306T (human)
hKCNQ2/var:A306T
Yes
organism-sequence


PR:000000914 voltage-gated potassium channel subunit KCNQ2 sequence variant R333Q (human)
hKCNQ2/var:R333Q
Yes
organism-sequence


PR:000000915 voltage-gated potassium channel subunit KCNQ2 sequence variant M208V (human)
hKCNQ2/var:M208V
Yes
organism-sequence


PR:O43526-1 potassium voltage-gated channel subfamily KQT member 2 isoform 1 (human)
hKCNQ2/iso:1

organism-sequence


PR:O43526-2 potassium voltage-gated channel subfamily KQT member 2 isoform 2 (human)
hKCNQ2/iso:2
Yes
organism-sequence


PR:O43526-3 potassium voltage-gated channel subfamily KQT member 2 isoform 3 (human)
hKCNQ2/iso:3

organism-sequence


PR:000000916 voltage-gated potassium channel subunit KCNQ2 isoform 3 sequence variant K526N (human)
hKCNQ2/iso:3/var:K526N
Yes
organism-sequence


PR:O43526-4 potassium voltage-gated channel subfamily KQT member 2 isoform 4 (human)
hKCNQ2/iso:4
Yes
organism-sequence


PR:O43526-5 potassium voltage-gated channel subfamily KQT member 2 isoform 5 (human)
hKCNQ2/iso:5

organism-sequence


PR:O43526-6 potassium voltage-gated channel subfamily KQT member 2 isoform 6 (human)
hKCNQ2/iso:6
Yes
organism-modification


PR:000076442 potassium voltage-gated channel subfamily KQT member 2 acetylated 1 (human)
hKCNQ2/Ac:1

organism-modification


PR:000079703 potassium voltage-gated channel subfamily KQT member 2 phosphorylated 1 (human)
hKCNQ2/Phos:1

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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Disease Associated GO Term
Protein Forms & Complexes
Evidence
DO:14264 benign neonatal seizuresPR:000000907 hKCNQ2/var:S247W PMID:12742592
PR:000000908 hKCNQ2/var:H228Q PMID:14534157
PR:000000909 hKCNQ2/var:R207W PMID:11572947
PR:000000910 hKCNQ2/var:L243F PMID:14534157
PR:000000911 hKCNQ2/var:4 PMID:11175290
PR:000000912 hKCNQ2/var:Y284C PMID:10788442
PR:000000913 hKCNQ2/var:A306T PMID:10788442
PR:000000914 hKCNQ2/var:R333Q PMID:14534157
PR:000000915 hKCNQ2/var:M208V PMID:14534157
PR:000000916 hKCNQ2/iso:3/var:K526N PMID:15249611

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0005249 voltage-gated potassium channel activityPR:000000907 hKCNQ2/var:S247W PMID:12742592
PR:000000909 hKCNQ2/var:R207W PMID:11572947
contributes_to GO:0005249 voltage-gated potassium channel activityPR:O43526-2 hKCNQ2/iso:2 PMID:11160379
decreased|contributes_to GO:0005249 voltage-gated potassium channel activityPR:O43526-6 hKCNQ2/iso:6 PMID:9039501
contributes_to GO:0005251 delayed rectifier potassium channel activityPR:O43526-4 hKCNQ2/iso:4 PMID:9836639

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0009986 cell surfacePR:000000912 hKCNQ2/var:Y284C PMID:10788442
PR:000000913 hKCNQ2/var:A306T PMID:10788442