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Protein Ontology report - gasdermin-E (human)
PR:O60443 - http://purl.obolibrary.org/obo/PR_O60443
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:O60443   
  PRO namegasdermin-E (human) 
  Synonyms
PRO-Short-label: EXACT:hGSDME
Gene-based: RELATED:DFNA5 | GSDME | ICERE1
Other: EXACT:ICERE-1 (human) | inversely correlated with estrogen receptor expression 1 (human) | non-syndromic hearing impairment protein 5 (human)
  Definition"A gasdermin-E that is encoded in the genome of human." [PRO:DNx, UniProtKB:O60443
  PRO Categoryorganism-gene 
  ParentPR:000006431 gasdermin-E
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:2810 GSDME (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 5                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:O60443
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
organism-gene



PR:O60443

gasdermin-E (human)

hGSDME


"A gasdermin-E that is encoded in the genome of human." [PRO:DNx, UniProtKB:O60443]


organism-sequence



PR:000061589

gasdermin-E sequence variant W46* (human)

hGSDME/var:W46*


"A gasdermin-E (human) that has has been truncated after the position equivalent to Cys-45 of the amino acid sequence represented by UniProtKB:O60443-1. Example: UniProtKB:O60443-1, 1-45." [PRO:DNx, Reactome:R-HSA-9711042]


organism-sequence



PR:000063384

gasdermin-E sequence variant E210* (human)

hGSDME/var:E210*


"A gasdermin-E (human) that has has been truncated after the position equivalent to Leu-209 of the amino acid sequence represented by UniProtKB:O60443-1. Example: UniProtKB:O60443-1, 1-209." [PRO:DNx, Reactome:R-HSA-9710420]


organism-sequence



PR:O60443-1

gasdermin-E isoform h1 (human)

hGSDME/iso:h1


"A gasdermin-E (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60443-1." [PRO:DNx, UniProtKB:O60443]


organism-sequence



PR:O60443-2

gasdermin-E isoform h2 (human)

hGSDME/iso:h2


"A gasdermin-E (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60443-2." [PRO:DNx, UniProtKB:O60443]


organism-sequence



PR:O60443-3

gasdermin-E isoform h3 (human)

hGSDME/iso:h3


"A gasdermin-E (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60443-3." [PRO:DNx, UniProtKB:O60443]


organism-modification



PR:000075954

gasdermin-E methylated 1 (human)

hGSDME/Me:1


"A gasdermin-E (human) that has been methylated on the residue at the position equivalent to Cys-417 of the amino acid sequence represented by UniProtKB:O60443-1. Example: UniProtKB:O60443-1, Cys-417, MOD:00660." [IEDB_epitope:1020823, IEDB_epitope:1031257, PRO:DNx]


organism-modification



PR:000080166

gasdermin-E methylated 2 (human)

hGSDME/Me:2


"A gasdermin-E (human) that has been methylated on the residue at the position equivalent to Cys-482 of the amino acid sequence represented by UniProtKB:O60443-1. Example: UniProtKB:O60443-1, Cys-482, MOD:00660." [IEDB_epitope:1027577, PRO:DNx]


organism-modification



PR:000080985

gasdermin-E methylated 3 (human)

hGSDME/Me:3


"A gasdermin-E (human) that has been methylated on the residue at the position equivalent to Cys-156 of the amino acid sequence represented by UniProtKB:O60443-1. Example: UniProtKB:O60443-1, Cys-156, MOD:00660." [IEDB_epitope:1010143, PRO:DNx]