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Protein Ontology report - prothrombin (human)
PR:P00734 - http://purl.obolibrary.org/obo/PR_P00734
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P00734   
  PRO nameprothrombin (human) 
  Synonyms
PRO-Short-label: EXACT:hF2
Gene-based: RELATED:F2
Other: EXACT:coagulation factor II (human)
  Definition"A prothrombin that is encoded in the genome of human." [PRO:DNx, UniProtKB:P00734] 
  PRO Categoryorganism-gene 
  ParentPR:000007299 prothrombin
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:3535 F2 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification0                                                  Organism-Modification 36                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P00734
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
organism-gene


PR:P00734
prothrombin (human)
hF2
"A prothrombin that is encoded in the genome of human." [PRO:DNx, UniProtKB:P00734]

organism-modification


PR:000047349
prothrombin, signal peptide removed form (human)
hF2/SigPep-
"A prothrombin (human) that has had the signal peptide removed. UniProtKB:P00734, 25-622." [PRO:DNx, Reactome:R-HSA-159739]

organism-modification


PR:000051038
prothrombin N-glycosylated 1 (human)
hF2/NGlyco:1
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-121 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P00734-1, Asn-121, MOD:00160~GNO:G00912UN." [GlyGen:P00734-1, PMID:22171320, PMID:24841998, PMID:29671580, PRO:DNx]

organism-modification


PR:000051039
prothrombin N-glycosylated 2 (human)
hF2/NGlyco:2
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-121 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G10486CT. Example: UniProtKB:P00734-1, Asn-121, MOD:00160~GNO:G10486CT." [GlyGen:P00734-1, PMID:22171320, PMID:24841998, PRO:DNx]

organism-modification


PR:000051040
prothrombin N-glycosylated 3 (human)
hF2/NGlyco:3
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-121 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:P00734-1, Asn-121, MOD:00160~GNO:G59626AS." [GlyGen:P00734-1, PMID:29671580, PRO:DNx]

organism-modification


PR:000051041
prothrombin N-glycosylated 4 (human)
hF2/NGlyco:4
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-121 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan structure is represented by GlyTouCan:G75850OP. Example: UniProtKB:P00734-1, Asn-121, MOD:00160~GNO:G75850OP." [GlyGen:P00734-1, PMID:7309709, PRO:DNx]

organism-modification


PR:000051042
prothrombin N-glycosylated 5 (human)
hF2/NGlyco:5
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-121 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan structure is represented by GlyTouCan:G84467IZ. Example: UniProtKB:P00734-1, Asn-121, MOD:00160~GNO:G84467IZ." [GlyGen:P00734-1, PMID:7309709, PRO:DNx]

organism-modification


PR:000051043
prothrombin N-glycosylated 6 (human)
hF2/NGlyco:6
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-121 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan structure is represented by GlyTouCan:G91365ZQ. Example: UniProtKB:P00734-1, Asn-121, MOD:00160~GNO:G91365ZQ." [GlyGen:P00734-1, PMID:7309709, PRO:DNx]

organism-modification


PR:000051044
prothrombin N-glycosylated 7 (human)
hF2/NGlyco:7
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-143 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P00734-1, Asn-143, MOD:00160~GNO:G00912UN." [GlyGen:P00734-1, PMID:29671580, PRO:DNx]

organism-modification


PR:000051045
prothrombin N-glycosylated 8 (human)
hF2/NGlyco:8
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-143 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G06247RL. Example: UniProtKB:P00734-1, Asn-143, MOD:00160~GNO:G06247RL." [GlyGen:P00734-1, PMID:29671580, PRO:DNx]

organism-modification


PR:000051046
prothrombin N-glycosylated 9 (human)
hF2/NGlyco:9
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-143 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G08293MJ. Example: UniProtKB:P00734-1, Asn-143, MOD:00160~GNO:G08293MJ." [GlyGen:P00734-1, PMID:29671580, PRO:DNx]

organism-modification


PR:000051047
prothrombin N-glycosylated 10 (human)
hF2/NGlyco:10
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-143 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G10486CT. Example: UniProtKB:P00734-1, Asn-143, MOD:00160~GNO:G10486CT." [GlyGen:P00734-1, PMID:22171320, PMID:29671580, PRO:DNx]

organism-modification


PR:000051048
prothrombin N-glycosylated 11 (human)
hF2/NGlyco:11
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-143 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G27947YN. Example: UniProtKB:P00734-1, Asn-143, MOD:00160~GNO:G27947YN." [GlyGen:P00734-1, PMID:29671580, PRO:DNx]

organism-modification


PR:000051049
prothrombin N-glycosylated 12 (human)
hF2/NGlyco:12
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-143 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G37399XV. Example: UniProtKB:P00734-1, Asn-143, MOD:00160~GNO:G37399XV." [GlyGen:P00734-1, PMID:29671580, PRO:DNx]

organism-modification


PR:000051050
prothrombin N-glycosylated 13 (human)
hF2/NGlyco:13
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-143 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan structure is represented by GlyTouCan:G42358LZ. Example: UniProtKB:P00734-1, Asn-143, MOD:00160~GNO:G42358LZ." [GlyGen:P00734-1, PMID:24279413, PRO:DNx]

organism-modification


PR:000051051
prothrombin N-glycosylated 14 (human)
hF2/NGlyco:14
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-143 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:P00734-1, Asn-143, MOD:00160~GNO:G59626AS." [GlyGen:P00734-1, PMID:29671580, PRO:DNx]

organism-modification


PR:000051052
prothrombin N-glycosylated 15 (human)
hF2/NGlyco:15
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-143 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan structure is represented by GlyTouCan:G75850OP. Example: UniProtKB:P00734-1, Asn-143, MOD:00160~GNO:G75850OP." [GlyGen:P00734-1, PMID:7309709, PRO:DNx]

organism-modification


PR:000051053
prothrombin N-glycosylated 16 (human)
hF2/NGlyco:16
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-143 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan structure is represented by GlyTouCan:G84467IZ. Example: UniProtKB:P00734-1, Asn-143, MOD:00160~GNO:G84467IZ." [GlyGen:P00734-1, PMID:7309709, PRO:DNx]

organism-modification


PR:000051054
prothrombin N-glycosylated 17 (human)
hF2/NGlyco:17
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-143 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G88374WZ. Example: UniProtKB:P00734-1, Asn-143, MOD:00160~GNO:G88374WZ." [GlyGen:P00734-1, PMID:29671580, PRO:DNx]

organism-modification


PR:000051055
prothrombin N-glycosylated 18 (human)
hF2/NGlyco:18
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-143 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan structure is represented by GlyTouCan:G91365ZQ. Example: UniProtKB:P00734-1, Asn-143, MOD:00160~GNO:G91365ZQ." [GlyGen:P00734-1, PMID:7309709, PRO:DNx]

organism-modification


PR:000051056
prothrombin N-glycosylated 19 (human)
hF2/NGlyco:19
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-143 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G94917XT. Example: UniProtKB:P00734-1, Asn-143, MOD:00160~GNO:G94917XT." [GlyGen:P00734-1, PMID:29671580, PRO:DNx]

organism-modification


PR:000051057
prothrombin N-glycosylated 20 (human)
hF2/NGlyco:20
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-143 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G95865ZB. Example: UniProtKB:P00734-1, Asn-143, MOD:00160~GNO:G95865ZB." [GlyGen:P00734-1, PMID:29671580, PRO:DNx]

organism-modification


PR:000051058
prothrombin N-glycosylated 21 (human)
hF2/NGlyco:21
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-416 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P00734-1, Asn-416, MOD:00160~GNO:G00912UN." [GlyGen:P00734-1, PMID:29671580, PRO:DNx]

organism-modification


PR:000051059
prothrombin N-glycosylated 22 (human)
hF2/NGlyco:22
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-416 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan structure is represented by GlyTouCan:G22140GZ. Example: UniProtKB:P00734-1, Asn-416, MOD:00160~GNO:G22140GZ." [GlyGen:P00734-1, PMID:19838169, PRO:DNx]

organism-modification


PR:000051060
prothrombin N-glycosylated 23 (human)
hF2/NGlyco:23
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-416 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan structure is represented by GlyTouCan:G42358LZ. Example: UniProtKB:P00734-1, Asn-416, MOD:00160~GNO:G42358LZ." [GlyGen:P00734-1, PMID:24279413, PRO:DNx]

organism-modification


PR:000051061
prothrombin N-glycosylated 24 (human)
hF2/NGlyco:24
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-416 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:P00734-1, Asn-416, MOD:00160~GNO:G59626AS." [GlyGen:P00734-1, PMID:29671580, PRO:DNx]

organism-modification


PR:000051062
prothrombin N-glycosylated 25 (human)
hF2/NGlyco:25
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-416 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan structure is represented by GlyTouCan:G75850OP. Example: UniProtKB:P00734-1, Asn-416, MOD:00160~GNO:G75850OP." [GlyGen:P00734-1, PMID:7309709, PRO:DNx]

organism-modification


PR:000051063
prothrombin N-glycosylated 26 (human)
hF2/NGlyco:26
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-416 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan structure is represented by GlyTouCan:G84467IZ. Example: UniProtKB:P00734-1, Asn-416, MOD:00160~GNO:G84467IZ." [GlyGen:P00734-1, PMID:7309709, PRO:DNx]

organism-modification


PR:000051064
prothrombin N-glycosylated 27 (human)
hF2/NGlyco:27
"A prothrombin (human) that has been N-glycosylated at the residue equivalent to Asn-416 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan structure is represented by GlyTouCan:G91365ZQ. Example: UniProtKB:P00734-1, Asn-416, MOD:00160~GNO:G91365ZQ." [GlyGen:P00734-1, PMID:7309709, PRO:DNx]

organism-modification


PR:000051065
prothrombin O-glycosylated 1 (human)
hF2/OGlyco:1
"A prothrombin (human) that has been O-glycosylated at the residue equivalent to Ser-207 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P00734-1, Ser-207, MOD:00002~GNO:G43417UB." [GlyGen:P00734-1, PMID:30459171, PRO:DNx]

organism-modification


PR:000051066
prothrombin O-glycosylated 2 (human)
hF2/OGlyco:2
"A prothrombin (human) that has been O-glycosylated at the residue equivalent to Thr-145 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P00734-1, Thr-145, MOD:00005~GNO:G43417UB." [GlyGen:P00734-1, PMID:30459171, PRO:DNx]

organism-modification


PR:000051067
prothrombin O-glycosylated 3 (human)
hF2/OGlyco:3
"A prothrombin (human) that has been O-glycosylated at the residue equivalent to Thr-192 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P00734-1, Thr-192, MOD:00005~GNO:G43417UB." [GlyGen:P00734-1, PMID:30459171, PRO:DNx]

organism-modification


PR:000051068
prothrombin O-glycosylated 4 (human)
hF2/OGlyco:4
"A prothrombin (human) that has been O-glycosylated at the residue equivalent to Thr-315 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P00734-1, Thr-315, MOD:00005~GNO:G43417UB." [GlyGen:P00734-1, PMID:30459171, PRO:DNx]

organism-modification


PR:000051069
prothrombin O-glycosylated 5 (human)
hF2/OGlyco:5
"A prothrombin (human) that has been O-glycosylated at the residue equivalent to Thr-317 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P00734-1, Thr-317, MOD:00005~GNO:G43417UB." [GlyGen:P00734-1, PMID:30459171, PRO:DNx]

organism-modification


PR:000051070
prothrombin O-glycosylated 6 (human)
hF2/OGlyco:6
"A prothrombin (human) that has been O-glycosylated at the residue equivalent to Thr-78 of the amino acid sequence represented by UniProtKB:P00734-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P00734-1, Thr-78, MOD:00005~GNO:G43417UB." [GlyGen:P00734-1, PMID:30459171, PRO:DNx]

organism-modification


PR:000062485
prothrombin, signal peptide removed carboxylated 1 (human)
hF2/SigPep-/Cbx:1
"A prothrombin (human) that has had the signal peptide removed and that has been carboxylated on the residues at the positions equivalent to Glu-49, Glu-50, Glu-57, Glu-59, Glu-62, Glu-63, Glu-68, Glu-69, Glu-72, and Glu-75 of the amino acid sequence represented by UniProtKB:P00734. UniProtKB:P00734, 25-622, Glu-49/Glu-50/Glu-57/Glu-59/Glu-62/Glu-63/Glu-68/Glu-69/Glu-72/Glu-75, MOD:00041." [PRO:DNx, Reactome:R-HSA-159800, Reactome:R-HSA-159841]

organism-modification


PR:000065732
prothrombin methylated 1 (human)
hF2/Me:1
"A prothrombin (human) that has been methylated on the residue at the position equivalent to Cys-336 of the amino acid sequence represented by UniProtKB:P00734. UniProtKB:P00734, Cys-336, MOD:00660." [IEDB_epitope:997771, PRO:DNx]