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Protein Ontology report - alpha-1-antitrypsin (human)
PR:P01009 - http://purl.obolibrary.org/obo/PR_P01009
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P01009   
  PRO namealpha-1-antitrypsin (human) 
  Synonyms
PRO-Short-label: EXACT:hSERPINA1
Gene-based: RELATED:AAT | PI | PRO0684 | PRO2209 | SERPINA1
Other: EXACT:alpha-1 protease inhibitor (human) | alpha-1-antiproteinase (human) | serpin A1 (human)
  Definition"An alpha-1-antitrypsin that is encoded in the genome of human." [PRO:CNA, UniProtKB:P01009
  PRO Categoryorganism-gene 
  ParentPR:000014678 alpha-1-antitrypsin
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:8941 SERPINA1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 37                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P01009
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
organism-gene



PR:P01009

alpha-1-antitrypsin (human)

hSERPINA1


"An alpha-1-antitrypsin that is encoded in the genome of human." [PRO:CNA, UniProtKB:P01009]


organism-sequence



PR:P01009-1

alpha-1-antitrypsin isoform h1 (human)

hSERPINA1/iso:h1


"An alpha-1-antitrypsin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01009-1." [PRO:DNx, UniProtKB:P01009]


organism-sequence



PR:P01009-2

alpha-1-antitrypsin isoform h2 (human)

hSERPINA1/iso:h2


"An alpha-1-antitrypsin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01009-2." [PRO:DNx, UniProtKB:P01009]


organism-sequence



PR:P01009-3

alpha-1-antitrypsin isoform h3 (human)

hSERPINA1/iso:h3


"An alpha-1-antitrypsin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P01009-3." [PRO:DNx, UniProtKB:P01009]


organism-modification



PR:000049204

alpha-1-antitrypsin, signal peptide removed form (human)

hSERPINA1/SigPep-


"An alpha-1-antitrypsin (human) that has had the signal peptide removed. UniProtKB:P01009, 25-418." [PRO:DNx, Reactome:R-HSA-141755, Reactome:R-HSA-141757]


organism-modification



PR:000051374

alpha-1-antitrypsin N-glycosylated 1 (human)

hSERPINA1/NGlyco:1


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-107 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P01009-1, Asn-107, MOD:00160~GNO:G00912UN." [GlyGen:P01009-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000051375

alpha-1-antitrypsin N-glycosylated 2 (human)

hSERPINA1/NGlyco:2


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-107 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan structure is represented by GlyTouCan:G22140GZ. Example: UniProtKB:P01009-1, Asn-107, MOD:00160~GNO:G22140GZ." [GlyGen:P01009-1, PMID:19838169, PRO:DNx]


organism-modification



PR:000051376

alpha-1-antitrypsin N-glycosylated 3 (human)

hSERPINA1/NGlyco:3


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-107 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan structure is represented by GlyTouCan:G36131WL. Example: UniProtKB:P01009-1, Asn-107, MOD:00160~GNO:G36131WL." [GlyGen:P01009-1, PMID:19838169, PRO:DNx]


organism-modification



PR:000051377

alpha-1-antitrypsin N-glycosylated 4 (human)

hSERPINA1/NGlyco:4


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-107 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan structure is represented by GlyTouCan:G36191CD. Example: UniProtKB:P01009-1, Asn-107, MOD:00160~GNO:G36191CD." [GlyGen:P01009-1, PMID:6966283, PMID:8390218, PRO:DNx]


organism-modification



PR:000051378

alpha-1-antitrypsin N-glycosylated 5 (human)

hSERPINA1/NGlyco:5


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-107 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan structure is represented by GlyTouCan:G78059CC. Example: UniProtKB:P01009-1, Asn-107, MOD:00160~GNO:G78059CC." [GlyGen:P01009-1, PMID:6966283, PMID:8390218, PRO:DNx]


organism-modification



PR:000051379

alpha-1-antitrypsin N-glycosylated 6 (human)

hSERPINA1/NGlyco:6


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-107 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan structure is represented by GlyTouCan:G84467IZ. Example: UniProtKB:P01009-1, Asn-107, MOD:00160~GNO:G84467IZ." [GlyGen:P01009-1, PMID:6966283, PMID:8390218, PRO:DNx]


organism-modification



PR:000051380

alpha-1-antitrypsin N-glycosylated 7 (human)

hSERPINA1/NGlyco:7


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-107 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan structure is represented by GlyTouCan:G92821YI. Example: UniProtKB:P01009-1, Asn-107, MOD:00160~GNO:G92821YI." [GlyGen:P01009-1, PMID:6966283, PMID:8390218, PRO:DNx]


organism-modification



PR:000051381

alpha-1-antitrypsin N-glycosylated 8 (human)

hSERPINA1/NGlyco:8


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-271 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P01009-1, Asn-271, MOD:00160~GNO:G00912UN." [GlyGen:P01009-1, PMID:22171320, PMID:24841998, PMID:26791533, PMID:29671580, PRO:DNx]


organism-modification



PR:000051382

alpha-1-antitrypsin N-glycosylated 9 (human)

hSERPINA1/NGlyco:9


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-271 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan composition is represented by GlyTouCan:G06247RL. Example: UniProtKB:P01009-1, Asn-271, MOD:00160~GNO:G06247RL." [GlyGen:P01009-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000051383

alpha-1-antitrypsin N-glycosylated 10 (human)

hSERPINA1/NGlyco:10


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-271 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan composition is represented by GlyTouCan:G08293MJ. Example: UniProtKB:P01009-1, Asn-271, MOD:00160~GNO:G08293MJ." [GlyGen:P01009-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000051384

alpha-1-antitrypsin N-glycosylated 11 (human)

hSERPINA1/NGlyco:11


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-271 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan composition is represented by GlyTouCan:G10486CT. Example: UniProtKB:P01009-1, Asn-271, MOD:00160~GNO:G10486CT." [GlyGen:P01009-1, PMID:22171320, PMID:24841998, PMID:29671580, PRO:DNx]


organism-modification



PR:000051385

alpha-1-antitrypsin N-glycosylated 12 (human)

hSERPINA1/NGlyco:12


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-271 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan structure is represented by GlyTouCan:G22140GZ. Example: UniProtKB:P01009-1, Asn-271, MOD:00160~GNO:G22140GZ." [GlyGen:P01009-1, PMID:19838169, PRO:DNx]


organism-modification



PR:000051386

alpha-1-antitrypsin N-glycosylated 13 (human)

hSERPINA1/NGlyco:13


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-271 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan composition is represented by GlyTouCan:G27947YN. Example: UniProtKB:P01009-1, Asn-271, MOD:00160~GNO:G27947YN." [GlyGen:P01009-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000051387

alpha-1-antitrypsin N-glycosylated 14 (human)

hSERPINA1/NGlyco:14


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-271 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan structure is represented by GlyTouCan:G36191CD. Example: UniProtKB:P01009-1, Asn-271, MOD:00160~GNO:G36191CD." [GlyGen:P01009-1, PMID:6966283, PMID:8390218, PRO:DNx]


organism-modification



PR:000051388

alpha-1-antitrypsin N-glycosylated 15 (human)

hSERPINA1/NGlyco:15


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-271 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan structure is represented by GlyTouCan:G42358LZ. Example: UniProtKB:P01009-1, Asn-271, MOD:00160~GNO:G42358LZ." [GlyGen:P01009-1, PMID:24279413, PRO:DNx]


organism-modification



PR:000051389

alpha-1-antitrypsin N-glycosylated 16 (human)

hSERPINA1/NGlyco:16


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-271 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan composition is represented by GlyTouCan:G45504EY. Example: UniProtKB:P01009-1, Asn-271, MOD:00160~GNO:G45504EY." [GlyGen:P01009-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000051390

alpha-1-antitrypsin N-glycosylated 17 (human)

hSERPINA1/NGlyco:17


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-271 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan composition is represented by GlyTouCan:G59626AS. Example: UniProtKB:P01009-1, Asn-271, MOD:00160~GNO:G59626AS." [GlyGen:P01009-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000051391

alpha-1-antitrypsin N-glycosylated 18 (human)

hSERPINA1/NGlyco:18


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-271 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan structure is represented by GlyTouCan:G78059CC. Example: UniProtKB:P01009-1, Asn-271, MOD:00160~GNO:G78059CC." [GlyGen:P01009-1, PMID:6966283, PMID:8390218, PRO:DNx]


organism-modification



PR:000051392

alpha-1-antitrypsin N-glycosylated 19 (human)

hSERPINA1/NGlyco:19


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-271 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan structure is represented by GlyTouCan:G84467IZ. Example: UniProtKB:P01009-1, Asn-271, MOD:00160~GNO:G84467IZ." [GlyGen:P01009-1, PMID:6966283, PMID:8390218, PRO:DNx]


organism-modification



PR:000051393

alpha-1-antitrypsin N-glycosylated 20 (human)

hSERPINA1/NGlyco:20


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-271 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan composition is represented by GlyTouCan:G88374WZ. Example: UniProtKB:P01009-1, Asn-271, MOD:00160~GNO:G88374WZ." [GlyGen:P01009-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000051394

alpha-1-antitrypsin N-glycosylated 21 (human)

hSERPINA1/NGlyco:21


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-271 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan structure is represented by GlyTouCan:G92821YI. Example: UniProtKB:P01009-1, Asn-271, MOD:00160~GNO:G92821YI." [GlyGen:P01009-1, PMID:6966283, PMID:8390218, PRO:DNx]


organism-modification



PR:000051395

alpha-1-antitrypsin N-glycosylated 22 (human)

hSERPINA1/NGlyco:22


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-271 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan composition is represented by GlyTouCan:G94917XT. Example: UniProtKB:P01009-1, Asn-271, MOD:00160~GNO:G94917XT." [GlyGen:P01009-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000051396

alpha-1-antitrypsin N-glycosylated 23 (human)

hSERPINA1/NGlyco:23


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-70 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:P01009-1, Asn-70, MOD:00160~GNO:G00912UN." [GlyGen:P01009-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000051397

alpha-1-antitrypsin N-glycosylated 24 (human)

hSERPINA1/NGlyco:24


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-70 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan composition is represented by GlyTouCan:G10486CT. Example: UniProtKB:P01009-1, Asn-70, MOD:00160~GNO:G10486CT." [GlyGen:P01009-1, PMID:22171320, PRO:DNx]


organism-modification



PR:000051398

alpha-1-antitrypsin N-glycosylated 25 (human)

hSERPINA1/NGlyco:25


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-70 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan structure is represented by GlyTouCan:G22140GZ. Example: UniProtKB:P01009-1, Asn-70, MOD:00160~GNO:G22140GZ." [GlyGen:P01009-1, PMID:19838169, PRO:DNx]


organism-modification



PR:000051399

alpha-1-antitrypsin N-glycosylated 26 (human)

hSERPINA1/NGlyco:26


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-70 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan structure is represented by GlyTouCan:G36191CD. Example: UniProtKB:P01009-1, Asn-70, MOD:00160~GNO:G36191CD." [GlyGen:P01009-1, PMID:6966283, PMID:8390218, PRO:DNx]


organism-modification



PR:000051400

alpha-1-antitrypsin N-glycosylated 27 (human)

hSERPINA1/NGlyco:27


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-70 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan structure is represented by GlyTouCan:G78059CC. Example: UniProtKB:P01009-1, Asn-70, MOD:00160~GNO:G78059CC." [GlyGen:P01009-1, PMID:6966283, PMID:8390218, PRO:DNx]


organism-modification



PR:000051401

alpha-1-antitrypsin N-glycosylated 28 (human)

hSERPINA1/NGlyco:28


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-70 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan structure is represented by GlyTouCan:G84467IZ. Example: UniProtKB:P01009-1, Asn-70, MOD:00160~GNO:G84467IZ." [GlyGen:P01009-1, PMID:6966283, PMID:8390218, PRO:DNx]


organism-modification



PR:000051402

alpha-1-antitrypsin N-glycosylated 29 (human)

hSERPINA1/NGlyco:29


"An alpha-1-antitrypsin (human) that has been N-glycosylated at the residue equivalent to Asn-70 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan structure is represented by GlyTouCan:G92821YI. Example: UniProtKB:P01009-1, Asn-70, MOD:00160~GNO:G92821YI." [GlyGen:P01009-1, PMID:6966283, PMID:8390218, PRO:DNx]


organism-modification



PR:000051403

alpha-1-antitrypsin O-glycosylated 1 (human)

hSERPINA1/OGlyco:1


"An alpha-1-antitrypsin (human) that has been O-glycosylated at the residue equivalent to Thr-109 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01009-1, Thr-109, MOD:00005~GNO:G43417UB." [GlyGen:P01009-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000051404

alpha-1-antitrypsin O-glycosylated 2 (human)

hSERPINA1/OGlyco:2


"An alpha-1-antitrypsin (human) that has been O-glycosylated at the residue equivalent to Thr-168 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01009-1, Thr-168, MOD:00005~GNO:G43417UB." [GlyGen:P01009-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000051405

alpha-1-antitrypsin O-glycosylated 3 (human)

hSERPINA1/OGlyco:3


"An alpha-1-antitrypsin (human) that has been O-glycosylated at the residue equivalent to Thr-35 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P01009-1, Thr-35, MOD:00005~GNO:G29068FM." [GlyGen:P01009-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000051406

alpha-1-antitrypsin O-glycosylated 4 (human)

hSERPINA1/OGlyco:4


"An alpha-1-antitrypsin (human) that has been O-glycosylated at the residue equivalent to Thr-35 of the amino acid sequence represented by UniProtKB:P01009-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P01009-1, Thr-35, MOD:00005~GNO:G43417UB." [GlyGen:P01009-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000060456

alpha-1-antitrypsin, signal peptide removed phosphorylated form (human)

hSERPINA1/SigPep-/PhosRes+


"An alpha-1-antitrypsin (human) that has had the signal peptide removed and that includes at least 1 phosphorylated residue. Example: UniProtKB:P01009-1, 25-418, MOD:00696." [PRO:DNx, Reactome:R-HSA-8957062]


organism-modification



PR:000064737

alpha-1-antitrypsin, signal peptide removed N-glycosylasparagine form (human)

hSERPINA1/SigPep-/NGlycoAsn+


"An alpha-1-antitrypsin (human) that has had the signal peptide removed and that includes at least 1 N-glycosylated asparagine. Example: UniProtKB:P01009-1, 25-418, MOD:00160." [PRO:DNx, Reactome:R-HSA-5689435, Reactome:R-HSA-5689731, Reactome:R-HSA-5689734]


organism-modification



PR:000066669

alpha-1-antitrypsin methylated 1 (human)

hSERPINA1/Me:1


"An alpha-1-antitrypsin (human) that has been methylated on the residue at the position equivalent to Cys-256 of the amino acid sequence represented by UniProtKB:P01009-1. Example: UniProtKB:P01009-1, Cys-256, MOD:00660." [IEDB_epitope:1042822, PRO:DNx]