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Protein Ontology report - Myc proto-oncogene protein (human)
PR:P01106 - http://purl.obolibrary.org/obo/PR_P01106
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:P01106   
  PRO nameMyc proto-oncogene protein (human) 
  Synonyms
PRO-Short-label: EXACT:hMYC
Gene-based: RELATED:BHLHE39 | MYC
Other: EXACT:class E basic helix-loop-helix protein 39 (human) | proto-oncogene c-Myc (human) | transcription factor p64 (human)
  Definition"A c-myc protein that is encoded in the genome of human." [PRO:CNA, UniProtKB:P01106] 
  PRO Categoryorganism-gene 
  ParentPR:000000084 c-myc protein
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:7553 MYC (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P01106
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
organism-gene


PR:P01106 Myc proto-oncogene protein (human)
hMYC

Yes
organism-sequence


PR:P01106-1 c-myc protein isoform 1 (human)
hMYC/iso:1
Yes
organism-modification


PR:000026033 c-myc protein isoform 1 acetylated 1 (human)
hMYC/iso:1/Ac:1
Yes
Yes
organism-modification


PR:000026038 c-myc protein isoform 1 unmodified form (human)
hMYC/iso:1/UnMod

Yes
organism-modification


PR:000026041 c-myc protein isoform 1 phosphorylated 4 (human)
hMYC/iso:1/Phos:4

organism-modification


PR:000026051 c-myc protein isoform 1 O-glycosylated 1 (human)
hMYC/iso:1/OGlyco:1
Yes
organism-modification


PR:000026054 c-myc protein isoform 1 phosphorylated 2 (human)
hMYC/iso:1/Phos:2
Yes
organism-modification


PR:000026055 c-myc protein isoform 1 phosphorylated 3 (human)
hMYC/iso:1/Phos:3
Yes
organism-modification


PR:000036448 c-myc protein isoform 1 phosphorylated 1 (human)
hMYC/iso:1/Phos:1
Yes
organism-sequence


PR:P01106-2 c-myc protein isoform 2 (human)
hMYC/iso:2
Yes
organism-sequence


PR:P01106-3 Myc proto-oncogene protein isoform h3 (human)
hMYC/iso:h3

organism-modification


PR:000048491 Myc proto-oncogene protein ubiquitinated form (human)
hMYC/UbiqLys+

organism-modification


PR:000077803 Myc proto-oncogene protein deaminated 1 (human)
hMYC/Deam:1

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hMYC forms found in complexes   

hMYC Component
 Complexes
PR:000026033 hMYC/iso:1/Ac:1 PR:000026035 Myc-max acetylated complex (human)
PR:000026038 hMYC/iso:1/UnMod PR:000026039 Myc-max complex 1 (human)
PR:P01106 hMYC PR:000025987 Myc-max complex (human)
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0006357 regulation of transcription by RNA polymerase IIPR:000026051 hMYC/iso:1/OGlyco:1 PMID:11904304
PR:P01106-1 hMYC/iso:1 PMID:16908182; PMID:2006410
GO:0008283 cell population proliferationPR:P01106-1 hMYC/iso:1 PMID:10962037
GO:0045766 positive regulation of angiogenesisPR:000026055 hMYC/iso:1/Phos:3 PMID:12676581
GO:0051726 regulation of cell cyclePR:P01106-1 hMYC/iso:1 PMID:10962037

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specificPR:000026051 hMYC/iso:1/OGlyco:1 PMID:11904304
GO:0003700 DNA-binding transcription factor activityPR:000026033 hMYC/iso:1/Ac:1 PMID:16126174
contributes_to GO:0003700 DNA-binding transcription factor activityPR:P01106-1 hMYC/iso:1 PMID:16908182; PMID:2006410
PR:P01106-2 hMYC/iso:2 PMID:3277717
NOT GO:0003700 DNA-binding transcription factor activityPR:000026054 hMYC/iso:1/Phos:2 PMID:7623799
GO:0005515 protein bindingPR:000036448 hMYC/iso:1/Phos:1 PMID:19131971
PR:P01106-1 hMYC/iso:1 PMID:12706874

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005634 nucleusPR:000026033 hMYC/iso:1/Ac:1 PMID:16126174
PR:000026055 hMYC/iso:1/Phos:3 PMID:12676581
GO:0005667 transcription factor complexPR:000026033 hMYC/iso:1/Ac:1 PMID:16126174
PR:P01106-1 hMYC/iso:1 PMID:16908182; PMID:2006410