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Protein Ontology report - estrogen receptor isoform 1 (human)
PR:P03372-1 -
http://purl.obolibrary.org/obo/PR_P03372-1
Protein Forms
Annotations
Ontology Information
Show OBO stanza
/
GPI
PRO ID
PR:P03372-1
PRO name
estrogen receptor isoform 1 (human)
Synonyms
PRO-Short-label
:
EXACT:
hESR1/iso:1
Definition
"An estrogen receptor isoform 1 that is encoded in the genome of human." [PRO:CNA]
Comment
Requested by=PubChem.
PRO Category
organism-sequence
Parent
PR:000027721
estrogen receptor isoform 1
PR:P03372
estrogen receptor (human)
Taxon
NCBITaxon:9606
Homo sapiens
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
0
Organism-Sequence
1
Modification
0
Organism-Modification
6
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:P03372-1
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Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
comp.
In Complex?
organism-sequence
PR:P03372-1
estrogen receptor isoform 1 (human)
hESR1/iso:1
"An estrogen receptor isoform 1 that is encoded in the genome of human." [PRO:CNA]
organism-modification
PR:000027724
estrogen receptor isoform 1 phosphorylated 1 (human)
hESR1/iso:1/Phos:1
"An estrogen receptor isoform 1 phosphorylated 1 in human. UniProtKB:P03372-1, Ser-167, MOD:00046." [PMID:19940156, PRO:PD]
Yes
organism-modification
PR:000027726
estrogen receptor isoform 1 phosphorylated 2 (human)
hESR1/iso:1/Phos:2
"An estrogen receptor isoform 1 phosphorylated 2 in human. UniProtKB:P03372-1, Tyr-52/Tyr-219, MOD:00048." [PMID:20101225, PRO:PD]
Yes
organism-modification
PR:000027754
estrogen receptor isoform 1 phosphorylated 3 (human)
hESR1/iso:1/Phos:3
"An estrogen receptor isoform 1 phosphorylated 3 in human. UniProtKB:P03372-1, Ser-118, MOD:00046." [PMID:17615152, PRO:PD]
organism-modification
PR:000027756
estrogen receptor isoform 1 acetylated 1 (human)
hESR1/iso:1/Ac:1
"An estrogen receptor isoform 1 acetylated 1 in human. UniProtKB:P03372-1, Lys-266/Lys-268, MOD:00064." [PMID:16497729, PRO:PD]
Yes
organism-modification
PR:000027776
estrogen receptor isoform 1 phosphorylated 4 (human)
hESR1/iso:1/Phos:4
"An estrogen receptor isoform 1 phosphorylated 4 in human. UniProtKB:P03372-1, Thr-311, MOD:00047." [PMID:12138194, PRO:PD]
Yes
organism-modification
PR:000027778
estrogen receptor isoform 1 phosphorylated 5 (human)
hESR1/iso:1/Phos:5
"An estrogen receptor isoform 1 phosphorylated 5 in human. UniProtKB:P03372-1, Ser-118/Ser-167, MOD:00046." [PMID:18941890, PRO:PD]
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000027724
hESR1/iso:1/Phos:1
UniProtKB:P03372-1, Ser-167, MOD:00046
acts_upstream_of_or_within
GO:0045893
positive regulation of DNA-templated transcription
PMID:19940156
PR:000027726
hESR1/iso:1/Phos:2
UniProtKB:P03372-1, Tyr-52/Tyr-219, MOD:00048
acts_upstream_of_or_within
GO:0010628
positive regulation of gene expression
PMID:20101225
enables
GO:0042803
protein homodimerization activity
PMID:20101225
located_in
GO:0005634
nucleus
PMID:20101225
PR:000027756
hESR1/iso:1/Ac:1
UniProtKB:P03372-1, Lys-266/Lys-268, MOD:00064
enables
GO:0003677
DNA binding
PMID:16497729
PR:000027776
hESR1/iso:1/Phos:4
UniProtKB:P03372-1, Thr-311, MOD:00047
acts_upstream_of_or_within
GO:0010628
positive regulation of gene expression
PMID:12138194
located_in
GO:0005634
nucleus
PMID:12138194