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Protein Ontology report - cellular tumor antigen p53 isoform 1 (human)
PR:P04637-1 - http://purl.obolibrary.org/obo/PR_P04637-1
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:P04637-1   
  PRO namecellular tumor antigen p53 isoform 1 (human) 
  Synonyms
PRO-Short-label: EXACT:hTP53/iso:1
  Definition"A cellular tumor antigen p53 isoform 1 that is encoded in the genome of human." [PMID:17671183, PMID:19252416, PRO:KER] 
  PRO Categoryorganism-sequence 
  ParentPR:000003036 cellular tumor antigen p53 isoform 1
PR:P04637 cellular tumor antigen p53 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence0                                                  Organism-Sequence 1                                        
         Modification0                                                  Organism-Modification 22                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P04637-1
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

comp. In Complex?
organism-sequence


PR:P04637-1 cellular tumor antigen p53 isoform 1 (human)
hTP53/iso:1
Yes
organism-modification


PR:000027764 cellular tumor antigen p53 isoform 1 phosphorylated 3 (human)
hTP53/iso:1/Phos:3

organism-modification


PR:000027766 cellular tumor antigen p53 isoform 1 dimethylated 1 (human)
hTP53/iso:1/Me2:1
Yes
organism-modification


PR:000027768 cellular tumor antigen p53 isoform 1 phosphorylated 4 (human)
hTP53/iso:1/Phos:4

organism-modification


PR:000027770 cellular tumor antigen p53 isoform 1 phosphorylated 5 (human)
hTP53/iso:1/Phos:5

organism-modification


PR:000027772 cellular tumor antigen p53 isoform 1 phosphorylated 6 (human)
hTP53/iso:1/Phos:6

organism-modification


PR:000027774 cellular tumor antigen p53 isoform 1 acetylated 1 (human)
hTP53/iso:1/Ac:1
Yes
organism-modification


PR:000027806 cellular tumor antigen p53 isoform 1 ubiquitinated 1 (human)
hTP53/iso:1/Ubiq:1

organism-modification


PR:000027808 cellular tumor antigen p53 isoform 1 methylated 3 (human)
hTP53/iso:1/Me:3
Yes
organism-modification


PR:000027810 cellular tumor antigen p53 isoform 1 methylated 4 (human)
hTP53/iso:1/Me:4
Yes
organism-modification


PR:000027812 cellular tumor antigen p53 isoform 1 acetylated 2 (human)
hTP53/iso:1/Ac:2
Yes
organism-modification


PR:000027814 cellular tumor antigen p53 isoform 1 phosphorylated 12 (human)
hTP53/iso:1/Phos:12
Yes
organism-modification


PR:000027827 cellular tumor antigen p53 isoform 1 dimethylated 2 (human)
hTP53/iso:1/Me2:2

organism-modification


PR:000027829 cellular tumor antigen p53 isoform 1 phosphorylated 7 (human)
hTP53/iso:1/Phos:7

organism-modification


PR:000027831 cellular tumor antigen p53 isoform 1 phosphorylated 8 (human)
hTP53/iso:1/Phos:8

organism-modification


PR:000027833 cellular tumor antigen p53 isoform 1 phosphorylated 9 (human)
hTP53/iso:1/Phos:9
Yes
organism-modification


PR:000027835 cellular tumor antigen p53 isoform 1 O-glycosylated 1 (human)
hTP53/iso:1/OGlyco:1

organism-modification


PR:000027837 cellular tumor antigen p53 isoform 1 phosphorylated 10 (human)
hTP53/iso:1/Phos:10

organism-modification


PR:000027839 cellular tumor antigen p53 isoform 1 phosphorylated 11 (human)
hTP53/iso:1/Phos:11
Yes
organism-modification


PR:000027841 cellular tumor antigen p53 isoform 1 sumoylated 1 (human)
hTP53/iso:1/Sumo:1

Yes
organism-modification


PR:000027846 cellular tumor antigen p53 isoform 1 unmodified form (human)
hTP53/iso:1/UnMod

Yes
organism-modification


PR:000035446 cellular tumor antigen p53 isoform 1 phosphorylated 1 (human)
hTP53/iso:1/Phos:1
Yes
organism-modification


PR:000036624 cellular tumor antigen p53 isoform 1 phosphorylated 2 (human)
hTP53/iso:1/Phos:2
Yes
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hTP53/iso:1 forms found in complexes   

hTP53/iso:1 Component
 Complexes
PR:000027841 hTP53/iso:1/Sumo:1 PR:000027844 p53 complex sumoylated 1 (human)
PR:000027846 hTP53/iso:1/UnMod PR:000027844 p53 complex sumoylated 1 (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000027766 hTP53/iso:1/Me2:1
UniProtKB:P04637-1, Lys-382, MOD:00084		 enablesGO:0005515 protein binding with PR:Q12888 53BP1 (human) PMID:18840612
PR:000027774 hTP53/iso:1/Ac:1
UniProtKB:P04637-1, Lys-120, MOD:00064		 acts_upstream_of_or_withinGO:0043065 positive regulation of apoptotic process PMID:17189187
PR:000027808 hTP53/iso:1/Me:3
UniProtKB:P04637-1, Lys-372, MOD:00663		 acts_upstream_of_or_withinGO:0045893 positive regulation of DNA-templated transcription PMID:15525938
located_inGO:0005634 nucleus PMID:15525938
PR:000027810 hTP53/iso:1/Me:4
UniProtKB:P04637-1, Lys-370, MOD:00663		 acts_upstream_of_or_withinGO:0045892 negative regulation of DNA-templated transcription PMID:17108971
PR:000027812 hTP53/iso:1/Ac:2
UniProtKB:P04637-1, Lys-382, MOD:00064		 acts_upstream_of_or_withinGO:0045893 positive regulation of DNA-templated transcription PMID:20228809
PR:000027814 hTP53/iso:1/Phos:12
UniProtKB:P04637-1, Ser-15/Ser-392, MOD:00046		 acts_upstream_of_or_withinGO:0045893 positive regulation of DNA-templated transcription PMID:21317932
located_inGO:0005634 nucleus PMID:21317932
PR:000027833 hTP53/iso:1/Phos:9
UniProtKB:P04637-1, Ser-15/Ser-37, MOD:00046		 acts_upstream_of_or_withinGO:0010468 regulation of gene expression PMID:14712210
PR:000027839 hTP53/iso:1/Phos:11
UniProtKB:P04637-1, Ser-183/Ser-269, MOD:00046|Thr-284, MOD:00047		 acts_upstream_of_or_withinGO:0010629 negative regulation of gene expression PMID:20959462
PR:000035446 hTP53/iso:1/Phos:1
UniProtKB:P04637-1, Ser-15, MOD:00046		 acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:11602639
located_inGO:0005634 nucleus PMID:11602639
PR:000036624 hTP53/iso:1/Phos:2
UniProtKB:P04637-1, Ser-15/Ser-46, MOD:00046		 acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:15642743
enablesGO:0005515 protein binding with PR:000003109 MAPK p38 active form PMID:15642743
PR:P04637-1 hTP53/iso:1 enablesGO:0005515 protein binding with PR:O43683 BUB1 PMID:17671183
GO:0005515 protein binding with PR:O60566 BUB1B PMID:17671183