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Protein Ontology report - T-cell-specific surface glycoprotein CD28 (human)
PR:P10747 - http://purl.obolibrary.org/obo/PR_P10747
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P10747   
  PRO nameT-cell-specific surface glycoprotein CD28 (human) 
  Synonyms
PRO-Short-label: EXACT:hCD28
Gene-based: RELATED:CD28
Other: EXACT:TP44 (human)
  Definition"A T-cell-specific surface glycoprotein CD28 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P10747
  PRO Categoryorganism-gene 
  ParentPR:000001841 T-cell-specific surface glycoprotein CD28
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:1653 CD28 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 7                                        
         Modification0                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P10747
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
organism-gene



PR:P10747

T-cell-specific surface glycoprotein CD28 (human)

hCD28


"A T-cell-specific surface glycoprotein CD28 that is encoded in the genome of human." [PRO:WCB, UniProtKB:P10747]


organism-sequence



PR:P10747-1

T-cell-specific surface glycoprotein CD28 isoform 1 (human)

hCD28/iso:1


"A T-cell-specific surface glycoprotein CD28 isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000025790

T-cell-specific surface glycoprotein CD28 isoform 1, signal peptide removed phosphorylated 1 (human)

hCD28/iso:1/SigPep-/Phos:1


"A T-cell-specific surface glycoprotein CD28 isoform 1, signal peptide removed phosphorylated 1 in human. UniProtKB:P10747-1, 19-220, Tyr-191, MOD:00048." [PMID:8992971, PRO:CNA]

Yes

Yes
organism-sequence



PR:P10747-2

T-cell-specific surface glycoprotein CD28 isoform h2 (human)

hCD28/iso:h2


"A T-cell-specific surface glycoprotein CD28 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10747-2." [PRO:DNx, UniProtKB:P10747]


organism-sequence



PR:P10747-3

T-cell-specific surface glycoprotein CD28 isoform h3 (human)

hCD28/iso:h3


"A T-cell-specific surface glycoprotein CD28 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10747-3." [PRO:DNx, UniProtKB:P10747]


organism-sequence



PR:P10747-4

T-cell-specific surface glycoprotein CD28 isoform h4 (human)

hCD28/iso:h4


"A T-cell-specific surface glycoprotein CD28 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10747-4." [PRO:DNx, UniProtKB:P10747]


organism-sequence



PR:P10747-5

T-cell-specific surface glycoprotein CD28 isoform h5 (human)

hCD28/iso:h5


"A T-cell-specific surface glycoprotein CD28 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10747-5." [PRO:DNx, UniProtKB:P10747]


organism-sequence



PR:P10747-6

T-cell-specific surface glycoprotein CD28 isoform h6 (human)

hCD28/iso:h6


"A T-cell-specific surface glycoprotein CD28 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10747-6." [PRO:DNx, UniProtKB:P10747]


organism-sequence



PR:P10747-7

T-cell-specific surface glycoprotein CD28 isoform h7 (human)

hCD28/iso:h7


"A T-cell-specific surface glycoprotein CD28 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10747-7." [PRO:DNx, UniProtKB:P10747]


organism-modification



PR:000026870

T-cell-specific surface glycoprotein CD28, signal peptide removed form (human)

hCD28/SigPep-


"A T-cell-specific surface glycoprotein CD28, signal peptide removed form in human. Example: UniProtKB:P10747-1, 19-220." [PRO:CNA, Reactome:R-HSA-167628, Reactome:R-HSA-167632]


organism-modification



PR:000025790

T-cell-specific surface glycoprotein CD28 isoform 1, signal peptide removed phosphorylated 1 (human)

hCD28/iso:1/SigPep-/Phos:1


"A T-cell-specific surface glycoprotein CD28 isoform 1, signal peptide removed phosphorylated 1 in human. UniProtKB:P10747-1, 19-220, Tyr-191, MOD:00048." [PMID:8992971, PRO:CNA]

Yes

Yes
organism-modification



PR:000071913

T-cell-specific surface glycoprotein CD28 cysteinylated 1 (human)

hCD28/Cyst:1


"A T-cell-specific surface glycoprotein CD28 (human) that has been cysteinylated on the residue at the position equivalent to Cys-66 of the amino acid sequence represented by UniProtKB:P10747-1. Example: UniProtKB:P10747-1, Cys-66, MOD:00765." [IEDB_epitope:1047728, PRO:DNx]


organism-modification



PR:000075395

T-cell-specific surface glycoprotein CD28 methylated 1 (human)

hCD28/Me:1


"A T-cell-specific surface glycoprotein CD28 (human) that has been methylated on the residue at the position equivalent to Cys-40 of the amino acid sequence represented by UniProtKB:P10747-1. Example: UniProtKB:P10747-1, Cys-40, MOD:00660." [IEDB_epitope:1035025, PRO:DNx]


organism-modification



PR:000078595

T-cell-specific surface glycoprotein CD28 methylated 2 (human)

hCD28/Me:2


"A T-cell-specific surface glycoprotein CD28 (human) that has been methylated on the residue at the position equivalent to Cys-66 of the amino acid sequence represented by UniProtKB:P10747-1. Example: UniProtKB:P10747-1, Cys-66, MOD:00660." [IEDB_epitope:1047729, PRO:DNx]


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hCD28 forms found in complexes   

hCD28 Component
Complexes
PR:000025790 hCD28/iso:1/SigPep-/Phos:1 PR:000025792 phospho CD28 homodimer (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000025790 hCD28/iso:1/SigPep-/Phos:1
UniProtKB:P10747-1, 19-220, Tyr-191, MOD:00048
located_inGO:0005886 plasma membrane Reactome:REACT_20178