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Protein Ontology report - cyclin-dependent kinase 2 (human)
PR:P24941 - http://purl.obolibrary.org/obo/PR_P24941
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P24941   
  PRO namecyclin-dependent kinase 2 (human) 
  Synonyms
PRO-Short-label: EXACT:hCDK2
Gene-based: RELATED:CDK2 | CDKN2
Other: EXACT:cell division protein kinase 2 (human) | p33 protein kinase (human)
  Definition"A cyclin-dependent kinase 2 that is encoded in the genome of human." [PRO:DNx] 
  PRO Categoryorganism-gene 
  ParentPR:000005253 cyclin-dependent kinase 2
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:1771 CDK2 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P24941
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

comp. In Complex?
organism-gene



PR:P24941

cyclin-dependent kinase 2 (human)

hCDK2


"A cyclin-dependent kinase 2 that is encoded in the genome of human." [PRO:DNx]


Yes
organism-sequence



PR:P24941-1

cyclin-dependent kinase 2 isoform h1 (human)

hCDK2/iso:h1


"A cyclin-dependent kinase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24941-1." [PRO:DNx, UniProtKB:P24941]


organism-sequence



PR:P24941-2

cyclin-dependent kinase 2 isoform h2 (human)

hCDK2/iso:h2


"A cyclin-dependent kinase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P24941-2." [PRO:DNx, UniProtKB:P24941]


organism-modification



PR:000028803

cyclin-dependent kinase 2 isoform 1 acetylated 1 (human)

hCDK2/iso:1/Ac:1


"A cyclin-dependent kinase 2 isoform 1 acetylated 1 in human. Acetylation inhibits CDK2 activity. UniProtKB:P24941-1, Lys-33, MOD:00064." [PMID:19773423, PRO:PD]


organism-modification



PR:000043632

cyclin-dependent kinase 2 phosphorylated form (human)

hCDK2/PhosRes+


"A cyclin-dependent kinase 2 phosphorylated form in human. UniProtKB:P24941, MOD:00696." [PRO:DAN]


Yes
organism-modification



PR:000045724

cyclin-dependent kinase 2 phosphorylated 1 (human)

hCDK2/Phos:1


"A cyclin-dependent kinase 2 (human) that has been phosphorylated on the residue at the position equivalent to Thr-160 of the amino acid sequence represented by UniProtKB:P24941-1. Example: UniProtKB:P24941-1, Thr-160, MOD:00047." [iPTMnet:P24941, PMID:12359725, PMID:14597612, PMID:17361108, PMID:8443411]


organism-modification



PR:000046674

cyclin-dependent kinase 2 phosphorylated 2 (human)

hCDK2/Phos:2


"A cyclin-dependent kinase 2 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-15 of the amino acid sequence represented by UniProtKB:P24941. UniProtKB:P24941, Tyr-15, MOD:00048." [PRO:DNx, Reactome:R-HSA-187905]


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hCDK2 forms found in complexes   

hCDK2 Component
Complexes
PR:000043632 hCDK2/PhosRes+ PR:000027151 cyclin E1:Cdk2 complex phosphorylated form (human)
PR:000027152 cyclin E2:Cdk2 complex phosphorylated form (human)
PR:P24941 hCDK2 PR:000026768 cyclin E1:Cdk2 complex (human)
PR:000026769 cyclin E2:Cdk2 complex (human)
PR:000028450 CDK2:CABLES1:Wee-1 (human)