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Protein Ontology report - DNA-(apurinic or apyrimidinic site) endonuclease (human)
PR:P27695 - http://purl.obolibrary.org/obo/PR_P27695
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P27695   
  PRO nameDNA-(apurinic or apyrimidinic site) endonuclease (human) 
  Synonyms
PRO-Short-label: EXACT:hAPEX1
Gene-based: RELATED:APE | APE1 | APEX | APEX1 | APX | HAP1 | REF1
Other: EXACT:AP endonuclease 1 (human) | APE-1 (human) | APEN (human) | APEX nuclease (human) | apurinic-apyrimidinic endonuclease 1 (human) | redox factor-1 (human) | REF-1 (human)
  Definition"A DNA-(apurinic or apyrimidinic site) endonuclease that is encoded in the genome of human." [PRO:DNx, UniProtKB:P27695] 
  PRO Categoryorganism-gene 
  ParentPR:000004127 DNA-(apurinic or apyrimidinic site) endonuclease
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:587 APEX1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P27695
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

comp. In Complex?
organism-gene


PR:P27695
DNA-(apurinic or apyrimidinic site) endonuclease (human)
hAPEX1
"A DNA-(apurinic or apyrimidinic site) endonuclease that is encoded in the genome of human." [PRO:DNx, UniProtKB:P27695]

organism-modification


PR:000046353
DNA-(apurinic or apyrimidinic site) endonuclease, initiator methionine removed form (human)
hAPEX1/InitMet-
"A DNA-(apurinic or apyrimidinic site) endonuclease (human) that has had the initiator methionine removed. UniProtKB:P27695, 2-318." [PRO:DNx, Reactome:R-HSA-50119]

organism-modification


PR:000069197
DNA-(apurinic or apyrimidinic site) endonuclease methylated 1 (human)
hAPEX1/Me:1
"A DNA-(apurinic or apyrimidinic site) endonuclease (human) that has been methylated on the residue at the position equivalent to Cys-310 of the amino acid sequence represented by UniProtKB:P27695. UniProtKB:P27695, Cys-310, MOD:00660." [IEDB_epitope:1005127, PRO:DNx]

organism-modification


PR:000075114
DNA-(apurinic or apyrimidinic site) endonuclease deaminated 1 (human)
hAPEX1/Deam:1
"A DNA-(apurinic or apyrimidinic site) endonuclease (human) that has been deaminated on the residue at the position equivalent to Asn-259 of the amino acid sequence represented by UniProtKB:P27695. UniProtKB:P27695, Asn-259, MOD:00684." [IEDB_epitope:1355979, PRO:DNx]

organism-modification


PR:000082098
DNA-(apurinic or apyrimidinic site) endonuclease methylated 2 (human)
hAPEX1/Me:2
"A DNA-(apurinic or apyrimidinic site) endonuclease (human) that has been methylated on the residue at the position equivalent to Cys-138 of the amino acid sequence represented by UniProtKB:P27695. UniProtKB:P27695, Cys-138, MOD:00660." [IEDB_epitope:1044559, PRO:DNx]